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Alexandria Venture Investments Portfolio Companies

Investor actively backing innovative startups and growth-stage companies across various industries and funding rounds.

Last updated: July 2026

Alexandria Venture Investments Investment Overview

Portfolio Companies
157
Total Invested
$3.8B
Average Investment
$37.7M

Alexandria Venture Investments's Most Recent Investments (2020+)

Company NameFoundedFunding StageAmountCity
Tr1x2025Venture - Series Unknown$50.0MSan Diego
AeroRx Therapeutics2025Series A$21.0MLa Jolla
Dualitas Therapeutics2025Series A$65.0MSan Francisco
Leal Therapeutics2025Series A$30.0MWorcester
GeneCentric Therapeutics2025Series C$8.0MDurham
Remedy Plan Therapeutics2025Venture - Series Unknown$18.0MGaithersburg
Hoofprint Biome2025Series A$15.0MRaleigh
Garuda Therapeutics2025Series A$50.0MCambridge
Ten63 Therapeutics2024Series AUndisclosedDurham
Pleno2024Series B$25.0MSan Diego

Complete List of Alexandria Venture Investments Portfolio Companies (157)

Export
#CompanyStageAmountLocation
26Tr1xVenture - Series Unknown$50.0MSan Diego, United States
27AeroRx TherapeuticsSeries A$21.0MLa Jolla, United States
28Dualitas TherapeuticsSeries A$65.0MSan Francisco, United States
29Leal TherapeuticsSeries A$30.0MWorcester, United States
30GeneCentric TherapeuticsSeries C$8.0MDurham, United States
31Remedy Plan TherapeuticsVenture - Series Unknown$18.0MGaithersburg, United States
32Hoofprint BiomeSeries A$15.0MRaleigh, United States
33Garuda TherapeuticsSeries A$50.0MCambridge, United States
34Ten63 TherapeuticsSeries AUndisclosedDurham, United States
35PlenoSeries B$25.0MSan Diego, United States
BiotechnologyHealth CareLife ScienceMedical

Tr1x is a biotechnology company developing novel cellular immunotherapies for patients with autoimmune and inflammatory diseases.

San Diego, United States
October 2025
$50.0M
Venture - Series Unknown

Founder Contacts

19,000+ verified contacts

Health CarePharmaceuticalWellness

AeroRx Therapeutics is a biopharmaceutical company that developing proprietary, combination products.

La Jolla, United States
October 2025
$21.0M
Series A

Founder Contacts

19,000+ verified contacts

Biotechnology

Dualitas Therapeutics is leading the way in bispecific antibody treatments for inflammatory and immunological (I&I) disorders

San Francisco, United States
September 2025
$65.0M
Series A

Founder Contacts

19,000+ verified contacts

MedicalTherapeutics

Leal Therapeutics develops novel therapeutics for patients.

Worcester, United States
August 2025
$30.0M
Series A

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CareHealth Diagnostics

GeneCentric Therapeutics develops and commercializes molecular diagnostic tests for oncologists and patients.

Durham, United States
June 2025
$8.0M
Series C

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth DiagnosticsMedicalTherapeutics

Remedy Plan is a pre-clinical cancer therapeutics company developing first-in-class small molecule drugs that differentiate cancer cells.

Gaithersburg, United States
May 2025
$18.0M
Venture - Series Unknown

Founder Contacts

19,000+ verified contacts

Animal FeedBiotechnologyLife ScienceLivestock

Hoofprint Biome is a biotechnology company that develops probiotics that improve the sustainability of ruminant livestock production.

Raleigh, United States
April 2025
$15.0M
Series A

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CareLife ScienceTherapeutics

Garuda Therapeutics develops off-the-shelf hematopoietic stem cell therapies to treat severe and life-threatening diseases.

Cambridge, United States
March 2025
$50.0M
Series A

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CareMedicalPharmaceutical

Ten63 Therapeutics is a venture-backed startup developing durable therapeutics against some of the world's most lethal diseases.

Durham, United States
December 2024
Series A

Founder Contacts

19,000+ verified contacts

BiopharmaBiotechnologyHealth CareHealth Diagnostics

Pleno is a biotechnology company that aims speeding up disease diagnosis and treatment.

San Diego, United States
December 2024
$25.0M
Series B

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CareTherapeutics

Jupiter BioVentures is a creation engine company that focuses on de-risking early-stage projects.

Delaware City, United States
November 2024
$70.0M
Venture - Series Unknown

Founder Contacts

19,000+ verified contacts

BioinformaticsBiopharmaBiotechnology

TRex Bio is a biotechnology company that treats diseases like cancer, fibrotic by studying human tissues.

South San Francisco, United States
November 2024
$84.0M
Series B

Founder Contacts

19,000+ verified contacts

BiotechnologyTherapeutics

CrossBridge Bio operates as a biotechnology company.

Houston, United States
November 2024
$10.0M
Seed

Founder Contacts

19,000+ verified contacts

BiotechnologyTherapeutics

Archon is a biotechnology firm that promotes next-generation antibody treatments through AI and computational protein design.

Washington, United States
October 2024
$20.0M
Seed

Founder Contacts

19,000+ verified contacts

BiotechnologyPharmaceuticalTherapeutics

Passkey Therapeutics is pioneering a new class of medicines, Synergistic Multifunctional Therapeutics (SMThs).

Cambridge, United States
October 2024
$20.0M
Seed

Founder Contacts

19,000+ verified contacts

Food ProcessingIntellectual PropertyOrganic Food

5Metis is a new pure-play discovery company for crop health.

Durham, United States
April 2024
$5.5M
Series A

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth Care

Early stage biotechnology company

Germantown, United States
December 2023
$29.9M
Venture - Series Unknown

Founder Contacts

19,000+ verified contacts

Health CareMedicalNeuroscienceTherapeutics

Arialys Therapeutics is a pre-clinical stage company that develops auto-antibody focusing on neuroscience.

La Jolla, United States
September 2023
$58.0M
Seed

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CarePharmaceutical

ROME Therapeutics is developing novel therapies for cancer and autoimmune diseases by harnessing the power of the repeatome.

Cambridge, United States
September 2023
$72.0M
Series B

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CareTherapeutics

Georgiamune is a biotechnology company developing next-generation immunotherapeutics for cancer and autoimmune diseases.

Gaithersburg, United States
August 2023
$75.0M
Series A

Founder Contacts

19,000+ verified contacts

BiotechnologyGeneticsHealth Care

TwinStrand Biosciences develops and commercializes the duplex sequencing technology for DNA sequencing.

Seattle, United States
June 2023
$10.3M
Venture - Series Unknown

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CareHealth DiagnosticsHospitalPrecision Medicine

Epic Sciences is a diagnostics company improving cancer management by providing real-time biopsy material to guide personalized medicine.

La Jolla, United States
April 2023
$24.0M
Series G

Founder Contacts

19,000+ verified contacts

Artificial Intelligence (AI)BiotechnologyManufacturingRobotics

Melonfrost is a biotechnology company based in Brooklyn, New York.

Brooklyn, United States
January 2023
$7.0M
Seed

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CareTherapeutics

Expansion Therapeutics is a biotechnology company focusing on developing transformative oral medicines for severe RNA-mediated diseases.

San Diego, United States
January 2023
$6.9M
Venture - Series Unknown

Founder Contacts

19,000+ verified contacts

AgricultureAgTechBiotechnologySustainability

Inari is a seed design and biotechnology company developing seeds for a nature-positive food system.

Cambridge, United States
January 2025
Series G

Founder Contacts

19,000+ verified contacts

Showing 26-50 of 157 portfolio companies

Frequently Asked Questions About Alexandria Venture Investments

How many companies has Alexandria Venture Investments invested in?

Alexandria Venture Investments has invested in 157 companies tracked in our database. The portfolio spans multiple industries and funding stages, from seed-stage startups to late-stage companies.

What industries does Alexandria Venture Investments invest in?

Alexandria Venture Investments's top investment sectors include Biotechnology, Health Care, Therapeutics, Medical, Pharmaceutical. The firm invests across 25 different industry categories.

What is Alexandria Venture Investments's largest investment?

Among tracked funding rounds, TRex Bio received $84.0M in a Series B round. Alexandria Venture Investments's total known invested capital is $3.8B.

What is the average investment size for Alexandria Venture Investments?

Alexandria Venture Investments's average investment size is $37.7M across its portfolio of 157 companies.

What are Alexandria Venture Investments's most recent investments?

Recent Alexandria Venture Investments portfolio additions include Tr1x, AeroRx Therapeutics, Dualitas Therapeutics, Leal Therapeutics, GeneCentric Therapeutics. These companies were founded in 2020 or later.

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