Janus Henderson Investors Portfolio Companies

Obsidian Therapeutics is a developer of a next-generation cell and gene therapies created to extend adoptive immunotherapy.

Climb Bio occurs when the immune system mistakenly attacks the body's tissues and can result in permanent organ damage or even death.

Edgewise Therapeutics is a clinical-stage biopharmaceutical company focused on the discovery, development and commercialization.

Maze Therapeutics is a biotechnology company that develops precision medicines for renal, cardiovascular, and metabolic diseases.

Ray Therapeutics is a biotech company that develops optogenetic gene therapies for patients with blinding diseases.

Calyxo is a medical device company that improves kidney stone treatment through specialized urology technologies.

AN2 Therapeutics focuses on modern biomedical and drug development expertise to provide transformational medicines.

Claris Biotherapeutics develops a topical formulation intended to cure corneal wounds, ulcers, and scars.

Solid Biosciences is a life science company that conducts research for the treatment of Duchenne muscular dystrophy.

Akero Therapeutics is a biotechnology company focused on reversing the NASH epidemic by restoring the body’s metabolism to a balanced state.

Ambrosia Biosciences offers drug development services for small molecule-based therapies for obesity and other metabolic disorders.

Palisade Bio is a clinical-stage biopharmaceutical company that develops therapies for acute and chronic gastrointestinal complications.

Stoke is developing antisense oligonucleotide medicines that target RNA splicing to increase gene expression for treatment.

Heartflow is a medical technology company that provides various methods of diagnosis and treatment of cardiovascular disease.

Nkarta Therapeutics is a developer of cell engineering platform created to build the next generation of cell therapies.

Arbor Biotechnologies is a biotechnology company specializing in next-generation gene editing therapeutics to treat genetic diseases.

Equillium is a biotechnology company that develops products for autoimmune and inflammatory disorders with an unmet medical need.

Longeveron is a biotechnology company that focuses on developing cellular therapies for chronic aging-related and life-threatening diseases.

Dianthus Therapeutics is a biotech company developing new treatments for serious autoimmune diseases using a more targeted approach.

Angitia Biopharmaceuticals develops biologic therapies for musculoskeletal diseases.

Applied Therapeutics uses drug-development approach to target molecules and pathways that has roles in fatal or debilitating diseases.

Bicara Therapeutics develops dual-action cancer therapies, combining targeted treatments with tumor modulators for enhanced impact.

Tyra Biosciences is a biotechnology company targeting new pathways of acquired resistance in oncology with purpose-built drugs.

Magnolia Medical Technologies is a device development company that focuses on improving the accuracy of diagnostic blood culture tests.

Immunic is a biopharmaceutical company that develops a pipeline of selective oral immunology therapies.