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MassChallenge Portfolio Companies

Investor actively backing innovative startups and growth-stage companies across various industries and funding rounds.

Last updated: June 2026

MassChallenge Investment Overview

Portfolio Companies
807
Total Invested
$3.4B
Average Investment
$6.6M

MassChallenge's Most Recent Investments (2020+)

Company NameFoundedFunding StageAmountCity
Natrion2026UndisclosedUndisclosedBinghamton
PerPlant2026SeedUndisclosedCopenhagen
Oklo2026Post-IPO EquityUndisclosedSanta Clara
Patientory2026Venture - Series UnknownUndisclosedAtlanta
Confidentialmind2026SeedUndisclosedEspoo
Naturbeads2026Grant$9.9MBath
Neurava2026Grant$1.6MBaltimore
MuukTest2026Grant$3.1MRaleigh
UMNAI2026Pre-Seed$1.0MLondon
Surf Therapeutics2026Venture - Series Unknown$6.0MAustin

Complete List of MassChallenge Portfolio Companies (807)

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#CompanyStageAmountLocation
1NatrionUndisclosedUndisclosedBinghamton, United States
2PerPlantSeedUndisclosedCopenhagen, Denmark
3OkloPost-IPO EquityUndisclosedSanta Clara, United States
4PatientoryVenture - Series UnknownUndisclosedAtlanta, United States
5ConfidentialmindSeedUndisclosedEspoo, Finland
6NaturbeadsGrant$9.9MBath, United Kingdom
7NeuravaGrant$1.6MBaltimore, United States
8MuukTestGrant$3.1MRaleigh, United States
9UMNAIPre-Seed$1.0MLondon, United Kingdom
10Surf TherapeuticsVenture - Series Unknown$6.0MAustin, United States
BatteryClean EnergyCleanTechEnergyEnergy StorageRenewable Energy

Natrion is developing scalable solid-state electrolytes to enable the mass adoption of EVs.

Binghamton, United States
May 2026
Undisclosed

Founder Contacts

19,000+ verified contacts

AgricultureAgTechArtificial Intelligence (AI)Computer VisionMachine LearningRobotics

PerPlant is a deep-ag tech startup building camera-based agronomic sensors for tractor and agricultural drones.

Copenhagen, Denmark
May 2026
Seed

Founder Contacts

19,000+ verified contacts

Artificial Intelligence (AI)Clean EnergyEnergyManufacturingNuclearRenewable EnergyVenture Capital

Oklo specializes in designing and developing small modular reactors for advanced fission power plants.

Santa Clara, United States
May 2026
Post-IPO Equity

Founder Contacts

19,000+ verified contacts

Artificial Intelligence (AI)BlockchainElectronic Health Record (EHR)Health CareSoftware

Patientory is a patient data platform that empowers individuals to control their health data and earn personalized rewards.

Atlanta, United States
April 2026
Venture - Series Unknown

Founder Contacts

19,000+ verified contacts

Artificial Intelligence (AI)Enterprise SoftwareMachine Learning

Confidentialmind is a B2B software company that provides a secure AI platform for enterprises.

Espoo, Finland
April 2026
Seed

Founder Contacts

19,000+ verified contacts

Advanced MaterialsBiotechnologyCleanTechManufacturing

Naturbeads is scaling up the technology to manufacture cellulose beads and replace plastic microbeads intentionally added to many products

Bath, United Kingdom
April 2026
$9.9M
Grant

Founder Contacts

19,000+ verified contacts

Health CareHealth DiagnosticsMedical Device

Neurava has developed wearable diagnostics for epilepsy patients including those at risk of SUDEP.

Baltimore, United States
April 2026
$1.6M
Grant

Founder Contacts

19,000+ verified contacts

Artificial Intelligence (AI)Information TechnologyQuality AssuranceSoftwareWeb Apps

MuukTest is a software testing platform powered by AI that increases Software Devs testing productivity.

Raleigh, United States
April 2026
$3.1M
Grant

Founder Contacts

19,000+ verified contacts

Artificial Intelligence (AI)FinTechMachine Learning

UMNAI specializes in neuro-symbolic machine learning and artificial intelligence and have created Hybrid Intelligence products.

London, United Kingdom
April 2026
$1.0M
Pre-Seed

Founder Contacts

19,000+ verified contacts

Health CareMedical

Surf Therapeutics is a clinical-stage firm leading the development of non-invasive ultrasound neuromodulation technology.

Austin, United States
April 2026
$6.0M
Venture - Series Unknown

Founder Contacts

19,000+ verified contacts

AgTechAquacultureRenewable Energy

Clean Valley CIC is a group of entrepreneurs, engineers and environmental scientists with a nature-inspired ideas for Canadian Innovation.

Dartmouth, Canada
March 2026
$4.0M
Debt Financing

Founder Contacts

19,000+ verified contacts

Health CareHealth DiagnosticsMedical Device

Starling develops predictive technology to identify chronic illnesses earlier.

Houston, United States
March 2026
$825K
Series Unknown

Founder Contacts

19,000+ verified contacts

AgricultureAgTechFarming

AgZen develops pesticide sprays stick to plants which reduces pollution and helps farmers save.

Somerville, United States
March 2026
$10.0M
Series B

Founder Contacts

19,000+ verified contacts

Health CareHealth DiagnosticsMobile AppsPersonal HealthSensor

Amulet provides consumer food allergen sensors that helps in testing for common allergenic ingredients in seconds.

Madison, United States
March 2026
$758K
Debt Financing

Founder Contacts

19,000+ verified contacts

Health CareMedicalMedical Device

ARMR Systems designs wearable first response hemorrhage control solutions to stop the bleeding anytime, anywhere.

Boston, United States
October 2025
$1.1M
Venture - Series Unknown

Founder Contacts

19,000+ verified contacts

Health CareHospitalLife ScienceSoftware

Folia Health is a platform that captures and shares secure health and symptom data for users.

Cambridge, United States
October 2025
$10.5M
Series A

Founder Contacts

19,000+ verified contacts

Cyber SecurityData GovernanceInformation TechnologyPrivacySecurity

Nymiz provides a definitive solution to ensure compliance with the GDPR regulations.

Bilbao, Spain
September 2025
$2.3M
Series A

Founder Contacts

19,000+ verified contacts

Alternative ProteinBiotechnologyBrewingFood and BeverageHardwareLife Science

Yeastime's value proposition is its innovative retrofitting ultrasound technology, which accelerates fermentation by up to 30%.

Rome, Italy
September 2025
$996K
Venture - Series Unknown

Founder Contacts

19,000+ verified contacts

EdTechSoftware

Organizational Management Platform for K-12 Schools.

Boston, United States
September 2025
$3.0M
Seed

Founder Contacts

19,000+ verified contacts

ChemicalRenewable Energy

RenewCO2 is a research company that develops processes for converting CO2 into polymers and chemicals.

Cranford, United States
August 2025
$4.2M
Seed

Founder Contacts

19,000+ verified contacts

Artificial Intelligence (AI)Consumer GoodsIndustrial AutomationManufacturingSensor

H2Ok Innovations transforms the operations of food and beverage factories through in-line sensors and AI solutions.

Cambridge, United States
July 2025
$12.0M
Series A

Founder Contacts

19,000+ verified contacts

AgricultureAgTechAnimal FeedArtificial Intelligence (AI)

Beewise offers robotic beehives that utilizes AI-powered precision robotics with minimal human intervention.

Bet Haemek, Israel
June 2025
$50.0M
Series D

Founder Contacts

19,000+ verified contacts

Artificial Intelligence (AI)ConstructionMachine LearningPredictive AnalyticsSensorSoftwareWireless

Construction Technology. Using sensors to capture the physical reality of the jobsite, and AI to optimise it.

London, United Kingdom
May 2025
$22.7M
Venture - Series Unknown

Founder Contacts

19,000+ verified contacts

AgricultureAgTechFarmingHorticultureSustainability

ClearLeaf uses patent-pending technology, organic certified in the EU and Japan, to control fungi and bacteria in agriculture.

Wilmington, United States
May 2025
$3.5M
Seed

Founder Contacts

19,000+ verified contacts

Health DiagnosticsMedical Device

PATH EX has developed a proprietary technology to selectively separate and capture bacteria and toxins from human blood.

Nashville, United States
May 2025
$5.0M
Venture - Series Unknown

Founder Contacts

19,000+ verified contacts

Showing 1-25 of 807 portfolio companies

Frequently Asked Questions About MassChallenge

How many companies has MassChallenge invested in?

MassChallenge has invested in 807 companies tracked in our database. The portfolio spans multiple industries and funding stages, from seed-stage startups to late-stage companies.

What industries does MassChallenge invest in?

MassChallenge's top investment sectors include Artificial Intelligence (AI), Health Care, AgTech, Software, Renewable Energy. The firm invests across 54 different industry categories.

What is MassChallenge's largest investment?

Among tracked funding rounds, Beewise received $50.0M in a Series D round. MassChallenge's total known invested capital is $3.4B.

What is the average investment size for MassChallenge?

MassChallenge's average investment size is $6.6M across its portfolio of 807 companies.

What are MassChallenge's most recent investments?

Recent MassChallenge portfolio additions include Natrion, PerPlant, Oklo, Patientory, Confidentialmind. These companies were founded in 2020 or later.

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