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MassChallenge Portfolio Companies

Investor actively backing innovative startups and growth-stage companies across various industries and funding rounds.

Last updated: June 2026

MassChallenge Investment Overview

Portfolio Companies
807
Total Invested
$3.8B
Average Investment
$7.5M

MassChallenge's Most Recent Investments (2020+)

Company NameFoundedFunding StageAmountCity
Ashored2023Grant$1.4MDartmouth
Beeverso (formerly BeeReaders)2023Seed$3.5MAustin
1upHealth2023Series C$40.0MBoston
DBeaver2023Seed$6.0MNew City
Sensegrass Inc2023Non Equity AssistanceUndisclosedSan Mateo
Relavo2023Seed$500KBaltimore
Reboot Rx2023Grant$1.0MBoston
Computational Life2023Convertible Note$300KDelaware
Equalize Digital2023Seed$300KGeorgetown
Kwema2023Pre-SeedUndisclosedSt Louis

Complete List of MassChallenge Portfolio Companies (807)

Export
#CompanyStageAmountLocation
451AshoredGrant$1.4MDartmouth, Canada
452Beeverso (formerly BeeReaders)Seed$3.5MAustin, United States
4531upHealthSeries C$40.0MBoston, United States
454DBeaverSeed$6.0MNew City, United States
455Sensegrass IncNon Equity AssistanceUndisclosedSan Mateo, United States
456RelavoSeed$500KBaltimore, United States
457Reboot RxGrant$1.0MBoston, United States
458Computational LifeConvertible Note$300KDelaware, United States
459Equalize DigitalSeed$300KGeorgetown, United States
460KwemaPre-SeedUndisclosedSt Louis, United States
Big DataCommunication HardwareHardwareMarine TechnologySensorSoftware

Technology for Profitable & Sustainable Ocean Harvests

Dartmouth, Canada
April 2023
$1.4M
Grant

Founder Contacts

19,000+ verified contacts

EdTechEducationLanguage Learning

Edtech company delivering digital solutions for PreK-12 Spanish literacy improvement

Austin, United States
April 2023
$3.5M
Seed

Founder Contacts

19,000+ verified contacts

Health CareHospitalMedicalMedical Device

1upHealth is a healthcare data platform operator that aggregates and shares medical data for patients, providers, and software developers.

Boston, United States
April 2023
$40.0M
Series C

Founder Contacts

19,000+ verified contacts

AnalyticsBig DataDatabaseDeveloper ToolsInformation TechnologyTechnical Support

IT company with 20 years of experience developing database management tools

New City, United States
April 2023
$6.0M
Seed

Founder Contacts

19,000+ verified contacts

AgricultureAgTechArtificial Intelligence (AI)FarmingInternet of Things

Sensegrass provides a platform for soil intelligence.

San Mateo, United States
April 2023
Non Equity Assistance

Founder Contacts

19,000+ verified contacts

Health Care

Relavo offers a device to prevent infection in peritoneal dialysis, a form of at-home treatment for end-stage renal disease.

Baltimore, United States
April 2023
$500K
Seed

Founder Contacts

19,000+ verified contacts

Artificial Intelligence (AI)GeneticsHealth CareOncology

Reboot Rx is a nonprofit health tech startup dedicated to fast-tracking the development of affordable cancer treatments.

Boston, United States
April 2023
$1.0M
Grant

Founder Contacts

19,000+ verified contacts

Health CareHealth DiagnosticsMedicalMedical DeviceSimulationSoftware

Computational Life is a digital avatar to design medical solutions.

Delaware, United States
April 2023
$300K
Convertible Note

Founder Contacts

19,000+ verified contacts

SaaSWeb AppsWeb DesignWeb Development

Equalize Digital is a Certified B Corporation that specializes in web accessibility products and consulting.

Georgetown, United States
March 2023
$300K
Seed

Founder Contacts

19,000+ verified contacts

Consumer ElectronicsEmployee BenefitsHealth CarePhysical SecuritySecurityWearables

Kwema created the world's first smart badge reel with a hidden duress button to unobtrusively call for help when facing workplace violence.

St Louis, United States
March 2023
Pre-Seed

Founder Contacts

19,000+ verified contacts

Advanced MaterialsInformation TechnologyNanotechnology

Graphene Composites is a nano-technology startup that combines graphene with aerogel .

Bincombe, United Kingdom
March 2023
$1.1M
Seed

Founder Contacts

19,000+ verified contacts

Consumer ElectronicsHealth CareParentingPersonal HealthWearables

Lilu is a women’s health company building tech-enabled devices to empower new moms.

New York, United States
March 2023
$1.0M
Seed

Founder Contacts

19,000+ verified contacts

ManufacturingMedicalMedical DeviceOncology

NU-RISE is a medical company that develops nuclear radiation sensors and equipment for cancer treatment.

Aveiro, Portugal
March 2023
$3.5M
Seed

Founder Contacts

19,000+ verified contacts

AppsEventsSports

CrowdPlay develops a fan engagement platform to engage with live sporting events.

Boston, United States
March 2023
$1.9M
Seed

Founder Contacts

19,000+ verified contacts

AquacultureBiotechnologyFarmingFood and BeverageFood Processing

Sustainable, high performance aquaculture feeds

Rome, Italy
February 2023
$668K
Pre-Seed

Founder Contacts

19,000+ verified contacts

Food and BeverageNutritionSnack Food

IQ Bar is a food and beverage company that offers protein bars and IQMIX hydration mixes.

Boston, United States
January 2023
$6.2M
Series Unknown

Founder Contacts

19,000+ verified contacts

EdTechEducationE-LearningSocial Impact

IDialogue connects children from radically different backgrounds for cross-cultural communication and collaborative projects.

Austin, United States
January 2023
$150K
Pre-Seed

Founder Contacts

19,000+ verified contacts

HardwareHospitalityLaundry and Dry-cleaning

Presso offers distributed micro-retail solution for ultra-fast dry-cleaning.

Atlanta, United States
January 2023
$8.0M
Seed

Founder Contacts

19,000+ verified contacts

AerospaceCloud ManagementEnterprise SoftwareInternet of ThingsReal Time

Cloud based management platform that provides real time visibility on the status of critical aircraft safety and security cabin equipment

Miami, United States
January 2023
Pre-Seed

Founder Contacts

19,000+ verified contacts

Artificial Intelligence (AI)Cloud Data ServicesLife ScienceRobotics

Vectech's AI diagnostic entomology system identifies damaging insects that spread disease and cause agricultural or economic loss.

Baltimore, United States
January 2023
$20K
Pre-Seed

Founder Contacts

19,000+ verified contacts

Ad RetargetingAd TargetingAdvertisingAdvertising PlatformsDigital MarketingEnterprise SoftwareMarketingMobileVideoVideo Advertising

ViralGains is the zero-party data gathering and advertising tool for finding, understanding, and nurturing new and returning customers.

Boston, United States
January 2023
Debt Financing

Founder Contacts

19,000+ verified contacts

Artificial Intelligence (AI)BiotechnologyHealth CareMedical

Glamorous AI is a developer of an artificial intelligence-based drug discovery platform.

London, United Kingdom
January 2023
Seed

Founder Contacts

19,000+ verified contacts

FinTechMobileSoftwareTelecommunicationsWater

CityTaps helps bring running water to every urban home, to boost the health, dignity.

Montrouge, France
January 2023
Series Unknown

Founder Contacts

19,000+ verified contacts

Information TechnologySecurityTelecommunications

The Whisper Company develops products and services for privacy and secure communication.

Austin, United States
December 2022
$250K
Seed

Founder Contacts

19,000+ verified contacts

Consumer ElectronicsHardwareLaw EnforcementRoboticsSensor

Throwable omnidirectional/360 cameras for first responders

Boston, United States
December 2022
Series A

Founder Contacts

19,000+ verified contacts

Showing 451-475 of 807 portfolio companies

Frequently Asked Questions About MassChallenge

How many companies has MassChallenge invested in?

MassChallenge has invested in 807 companies tracked in our database. The portfolio spans multiple industries and funding stages, from seed-stage startups to late-stage companies.

What industries does MassChallenge invest in?

MassChallenge's top investment sectors include Health Care, Medical, Artificial Intelligence (AI), Hardware, Software. The firm invests across 74 different industry categories.

What is MassChallenge's largest investment?

Among tracked funding rounds, 1upHealth received $40.0M in a Series C round. MassChallenge's total known invested capital is $3.8B.

What is the average investment size for MassChallenge?

MassChallenge's average investment size is $7.5M across its portfolio of 807 companies.

What are MassChallenge's most recent investments?

Recent MassChallenge portfolio additions include Ashored, Beeverso (formerly BeeReaders), 1upHealth, DBeaver, Sensegrass Inc. These companies were founded in 2020 or later.

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