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National Institutes of Health Portfolio Companies

Investor actively backing innovative startups and growth-stage companies across various industries and funding rounds.

Last updated: June 2026

National Institutes of Health Investment Overview

Portfolio Companies
288
Total Invested
$1.3B
Average Investment
$6.6M

National Institutes of Health's Most Recent Investments (2020+)

Company NameFoundedFunding StageAmountCity
Oxalo Therapeutics2022Grant$1000KChicago
PolyCore Therapeutics2022SeedUndisclosedPhiladelphia
Dascena2022GrantUndisclosedHouston
Enspectra Health2022Grant$1.2MMenlo Park
Arc Bio LLC2022Grant$1.9MMenlo Park
Epitel2022Series A$12.5MSalt Lake City
Lightengale2022Grant$50KDecatur
HealthRhythms2022Seed$11.0MLong Island City
Anavasi Diagnostics2022Convertible Note$6.0MSeattle
Trace Matters2022Grant$350KSomerville

Complete List of National Institutes of Health Portfolio Companies (288)

Export
#CompanyStageAmountLocation
226Oxalo TherapeuticsGrant$1000KChicago, United States
227PolyCore TherapeuticsSeedUndisclosedPhiladelphia, United States
228DascenaGrantUndisclosedHouston, United States
229Enspectra HealthGrant$1.2MMenlo Park, United States
230Arc Bio LLCGrant$1.9MMenlo Park, United States
231EpitelSeries A$12.5MSalt Lake City, United States
232LightengaleGrant$50KDecatur, United States
233HealthRhythmsSeed$11.0MLong Island City, United States
234Anavasi DiagnosticsConvertible Note$6.0MSeattle, United States
235Trace MattersGrant$350KSomerville, United States
BiotechnologyClinical TrialsMedicalTherapeutics

Oxalo Therapeutics creates drugs to treat rare kidney diseases and prevent recurring kidney stones.

Chicago, United States
April 2022
$1000K
Grant

Founder Contacts

19,000+ verified contacts

Health CareProfessional ServicesTherapeutics

PolyCore Therapeutics’ team of life sciences scientists is dedicated to developing breakthrough treatments for CNS Diseases.

Philadelphia, United States
April 2022
Seed

Founder Contacts

19,000+ verified contacts

Big DataBiotechnologyHealth CareMachine LearningMedical DevicePredictive Analytics

Dascena develops machine learning algorithms to enable early disease intervention and improve care outcomes for patients.

Houston, United States
March 2022
Grant

Founder Contacts

19,000+ verified contacts

Health CareMedical

Enspectra Health is a digital transformation in pathology by imaging cellular anatomy.

Menlo Park, United States
March 2022
$1.2M
Grant

Founder Contacts

19,000+ verified contacts

Biotechnology

Arc Bio provides research and development in the physical, engineering, and life sciences.

Menlo Park, United States
February 2022
$1.9M
Grant

Founder Contacts

19,000+ verified contacts

Emergency MedicineHealth CareHealth DiagnosticsHome Health CareHospitalMedicalMedical DevicemHealthNeuroscience

Epitel is empowering clinicians, patients, and caregivers who live with or care for neurological disorders with wearables and powerful AI.

Salt Lake City, United States
February 2022
$12.5M
Series A

Founder Contacts

19,000+ verified contacts

Health CareHospital

Lightengale develops medical devices for improved ICU infusion lines.

Decatur, United States
February 2022
$50K
Grant

Founder Contacts

19,000+ verified contacts

Health CareMachine LearningMental HealthMobileSensor

HealthRhythms develops a mental health assessment and treatment platform to measure and monitor health conditions.

Long Island City, United States
February 2022
$11.0M
Seed

Founder Contacts

19,000+ verified contacts

BiotechnologyManufacturingMedicalMedical Device

Anavasi Diagnostics is a medical technology company that focuses on the development of molecular diagnostic testing.

Seattle, United States
January 2022
$6.0M
Convertible Note

Founder Contacts

19,000+ verified contacts

BiotechnologyMedical DeviceSpace Travel

Trace Matters is a technology startup focused on developing next generation of mass spectrometry technologies for a variety of applications.

Somerville, United States
January 2022
$350K
Grant

Founder Contacts

19,000+ verified contacts

Health CareMedical

Bleep provides best new CPAP solution on the market.

Chapel Hill, United States
December 2021
$1.7M
Grant

Founder Contacts

19,000+ verified contacts

BiotechnologyGeneticsHealth CareMedicalTherapeutics

CODA Biotherapeutics develops a chemogenetic platform designed to modulate neuronal activity.

South San Francisco, United States
December 2021
$28.0M
Series Unknown

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CarePharmaceuticalTherapeutics

4E Therapeutics is a neuroscience company that develops therapies for chronic neuropathic pain.

Austin, United States
November 2021
$5.5M
Grant

Founder Contacts

19,000+ verified contacts

BiotechnologyPharmaceutical

Biotechnology company inspired by globin chemistry and protein engineering focused on developing breakthrough antidotal therapies.

Pittsburgh, United States
November 2021
$750K
Grant

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CareHospitalMedical

Fauna Bio is a biotechnology company leveraging the science of hibernation to improve healthcare for humans.

Berkeley, United States
September 2021
$9.0M
Seed

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CareInnovation ManagementSocial ImpactSoftware

dfusion, a team of scientists and innovators, develops technology to promote evidence-based, health-related behavioral changes.

Scotts Valley, United States
September 2021
$1.7M
Grant

Founder Contacts

19,000+ verified contacts

Health CareMedical Device

Vibrato Medical is a medical device company developing wearable treatments for peripheral arterial disease.

Newport Beach, United States
September 2021
$4.0M
Series A

Founder Contacts

19,000+ verified contacts

Health CareHospitalRisk Management

Tabula Rasa enables medication optimization using its medication risk mitigation technology.

Moorestown, United States
August 2021
$1.9M
Grant

Founder Contacts

19,000+ verified contacts

BiotechnologyGeneticsHealth DiagnosticsMedical

ID Genomics specializes in nucleotide sequence-based molecular diagnostics and epidemiologic analysis of microbial pathogens.

Seattle, United States
August 2021
$300K
Grant

Founder Contacts

19,000+ verified contacts

BiopharmaBiotechnologyHealth CareNeuroscience

Cerecor discovers, develops and commercializes neuroscience drugs.

Baltimore, United States
August 2021
$10.0M
Post Ipo Debt

Founder Contacts

19,000+ verified contacts

Developer ToolsEnterprise SoftwareHealth Care

Xtrava is a developer of applications for health and wellness.

Santa Clara, United States
April 2021
$6.2M
Grant

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CareHealth DiagnosticsMedical

Quadrant Biosciences is an epigenetic diagnostics company focusing on the early detection of neurological disorders.

Syracuse, United States
April 2021
$417K
Equity Crowdfunding

Founder Contacts

19,000+ verified contacts

AnalyticsBiotechnologyDeveloper ToolsInformation TechnologyNeuroscience

Visikol is a contract research organization focused on digital pathology, 3D tissue imaging and 3D cell culture assays and models.

Whitehouse Station, United States
April 2021
$1.6M
Grant

Founder Contacts

19,000+ verified contacts

BiotechnologyTherapeutics

Avexegen Therapeutics is a biotechnology company developing therapies for gastrointestinal disorders.

San Diego, United States
February 2021
$2.9M
Grant

Founder Contacts

19,000+ verified contacts

Health CareMedicalNeuroscience

NeuraMedica is a medical device company developing a novel, bioabsorbable surgical clip to provide closure of the dura mater.

Oregon City, United States
February 2021
$1.1M
Series Unknown

Founder Contacts

19,000+ verified contacts

Showing 226-250 of 288 portfolio companies

Frequently Asked Questions About National Institutes of Health

How many companies has National Institutes of Health invested in?

National Institutes of Health has invested in 288 companies tracked in our database. The portfolio spans multiple industries and funding stages, from seed-stage startups to late-stage companies.

What industries does National Institutes of Health invest in?

National Institutes of Health's top investment sectors include Health Care, Biotechnology, Medical, Therapeutics, Medical Device. The firm invests across 32 different industry categories.

What is National Institutes of Health's largest investment?

Among tracked funding rounds, CODA Biotherapeutics received $28.0M in a Series Unknown round. National Institutes of Health's total known invested capital is $1.3B.

What is the average investment size for National Institutes of Health?

National Institutes of Health's average investment size is $6.6M across its portfolio of 288 companies.

What are National Institutes of Health's most recent investments?

Recent National Institutes of Health portfolio additions include Oxalo Therapeutics, PolyCore Therapeutics, Dascena, Enspectra Health, Arc Bio LLC. These companies were founded in 2020 or later.

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