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National Science Foundation Portfolio Companies

Investor actively backing innovative startups and growth-stage companies across various industries and funding rounds.

Last updated: July 2026

National Science Foundation Investment Overview

Portfolio Companies
2,009
Total Invested
$6.8B
Average Investment
$5.9M

National Science Foundation's Most Recent Investments (2020+)

Company NameFoundedFunding StageAmountCity
OpenRefactory2023SeedUndisclosedMilpitas
Octet Scientific2025SeedUndisclosedCleveland
futuresTHRIVE2022GrantUndisclosedDarien
Autonomys2022UndisclosedUndisclosedPalo Alto
Antithesis Foods2022GrantUndisclosedIthaca
Indrio Technologies2022GrantUndisclosedRiverside
Ramona2026Venture - Series UnknownUndisclosedDurham
Novaurum Biosciences2025GrantUndisclosedSomerville
Innatrix2022Convertible NoteUndisclosedDurham
CoreMap2022Series BUndisclosedBurlington

Complete List of National Science Foundation Portfolio Companies (2,009)

Export
#CompanyStageAmountLocation
251OpenRefactorySeedUndisclosedMilpitas, United States
252Octet ScientificSeedUndisclosedCleveland, United States
253futuresTHRIVEGrantUndisclosedDarien, United States
254AutonomysUndisclosedUndisclosedPalo Alto, United States
255Antithesis FoodsGrantUndisclosedIthaca, United States
256Indrio TechnologiesGrantUndisclosedRiverside, United States
257RamonaVenture - Series UnknownUndisclosedDurham, United States
258Novaurum BiosciencesGrantUndisclosedSomerville, United States
259InnatrixConvertible NoteUndisclosedDurham, United States
260CoreMapSeries BUndisclosedBurlington, United States
Cyber SecurityDeveloper ToolsSecurity

OpenRefactory helps enterprises manage the security risk associated with vulnerabilities in their FOSS infrastructure and their own code

Milpitas, United States
March 2023
Seed

Founder Contacts

19,000+ verified contacts

BatteryChemicalEnergyIndustrial Manufacturing

Octet Scientific addresses an unmet need for optimized chemistry in the Zinc Battery industry.

Cleveland, United States
March 2025
Seed

Founder Contacts

19,000+ verified contacts

Artificial Intelligence (AI)Health CareMachine LearningMental HealthSoftwareWellness

FuturesTHRIVE develops an AI platform to identify and track pediatric mental health easily.

Darien, United States
March 2022
Grant

Founder Contacts

19,000+ verified contacts

Artificial Intelligence (AI)BlockchainInformation TechnologyInternetWeb3

Subspace is an open, scalable platform for both storage and compute that is fully interoperable with any layer one.

Palo Alto, United States
March 2022
Undisclosed

Founder Contacts

19,000+ verified contacts

Food and BeverageFood Processing

Antithesis Foods produces health-conscious snacks such as chips, cookies, and crackers with nutrition.

Ithaca, United States
March 2022
Grant

Founder Contacts

19,000+ verified contacts

ChemicalElectronicsIndustrial AutomationLaserSensor

Indrio's patented laser-based chemical detection technology is poised to disrupt the 32B chemical sensor iot space.

Riverside, United States
March 2022
Grant

Founder Contacts

19,000+ verified contacts

BiotechnologyHardwareLife ScienceMachine LearningSoftware

Ramona develops high-throughput microscopy tools to unlock previously impossible experiments within the modern biology lab.

Durham, United States
March 2026
Venture - Series Unknown

Founder Contacts

19,000+ verified contacts

BiotechnologyMedicalNanotechnology

Novaurum Bioscience creates nano-biological coatings for medical implants to reduce infections and enhance healing.

Somerville, United States
March 2025
Grant

Founder Contacts

19,000+ verified contacts

AgricultureBiotechnologyChemical

Innatrix is an agricultural biotechnology company developing novel biological and chemical products.

Durham, United States
March 2022
Convertible Note

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CareMedical Device

CoreMap exists to improve patient outcomes by delivering advanced diagnostic technology to electrophysiologists and patients.

Burlington, United States
February 2022
Series B

Founder Contacts

19,000+ verified contacts

Artificial Intelligence (AI)AutomotiveAutonomous Vehicles

Mapless AI is a research company that develops safe alternatives for transportation systems.

Pittsburgh, United States
February 2024
Grant

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CareMedical

Creative BioTherapeutics is a biotechnology company developing therapies for cancer and viruses.

Gurnee, United States
February 2023
Undisclosed

Founder Contacts

19,000+ verified contacts

Cyber SecurityFile SharingInformation TechnologySoftware

Kapalya protects corporate data by encrypting files on end-points, corporate servers, and public cloud providers.

Berkeley, United States
February 2022
Equity Crowdfunding

Founder Contacts

19,000+ verified contacts

EnergyOil and Gas

Carnot maintains an isothermal compression process that functions as an optimized air and gas compression method.

Scotts Valley, United States
February 2023
Equity Crowdfunding

Founder Contacts

19,000+ verified contacts

Artificial Intelligence (AI)Industrial AutomationMining TechnologyRoboticsSpace Travel

OffWorld is developing AI-powered rugged robots for heavy industrial jobs in the mining, infrastructure, and space sectors.

Altadena, United States
February 2022
Grant

Founder Contacts

19,000+ verified contacts

Information and Communications Technology (ICT)Information TechnologyQuantum ComputingSoftware

Super.tech develops software that speeds up quantum computing by bridging the gap between applications and hardware.

Chicago, United States
February 2022
Grant

Founder Contacts

19,000+ verified contacts

Biotechnology

Visicell Medical is a developer of safe and biodegradable stem cell tracking tools.

San Diego, United States
February 2022
Grant

Founder Contacts

19,000+ verified contacts

BiotechnologyGeneticsLife Science

Acrigen Biosciences is dedicated to making gene editing safe.

Berkeley, United States
February 2022
Grant

Founder Contacts

19,000+ verified contacts

EnergyLighting

Allumia funds, designs, install and maintain a lighting upgrade for commercial and industrial customers.

Seattle, United States
February 2023
Convertible Note

Founder Contacts

19,000+ verified contacts

IndustrialIndustrial ManufacturingPrecious Metals

Paramium Technologies develops precise, freeform curved metal panels for custom-shaped radio reflectors.

Tucson, United States
February 2023
Grant

Founder Contacts

19,000+ verified contacts

BiotechnologyPlastics and Rubber ManufacturingProduct Research

Birch Biosciences is a biotechnology research firm that specializes in recycling plastic using enzymes.

Portland, United States
February 2023
Grant

Founder Contacts

19,000+ verified contacts

AssociationEducationE-LearningNon ProfitSaaSWeb Design

MathBRIX is a highly visual, concept-based approach to teaching math, backed by decades of research.

St Louis, United States
February 2024
Grant

Founder Contacts

19,000+ verified contacts

Industrial Automation

Artimus Robotics provides life-like motion to the next generation of robotics and automation.

Boulder, United States
February 2025
Grant

Founder Contacts

19,000+ verified contacts

Health CareHealth DiagnosticsHome Health CarePersonal HealthWellness

A continuous, passive, home-health remote monitoring platform.

Raleigh, United States
February 2025
Pre-Seed

Founder Contacts

19,000+ verified contacts

AgricultureFarmingRobotics

RowBot Systems develops and provides a robotic machine that allows farmers to practice in-season nitrogen management.

Minneapolis, United States
February 2026
Seed

Founder Contacts

19,000+ verified contacts

Showing 251-275 of 2,009 portfolio companies

Frequently Asked Questions About National Science Foundation

How many companies has National Science Foundation invested in?

National Science Foundation has invested in 2,009 companies tracked in our database. The portfolio spans multiple industries and funding stages, from seed-stage startups to late-stage companies.

What industries does National Science Foundation invest in?

National Science Foundation's top investment sectors include Biotechnology, Artificial Intelligence (AI), Health Care, Software, Chemical. The firm invests across 55 different industry categories.

What is the average investment size for National Science Foundation?

National Science Foundation's average investment size is $5.9M across its portfolio of 2,009 companies.

What are National Science Foundation's most recent investments?

Recent National Science Foundation portfolio additions include OpenRefactory, Octet Scientific, futuresTHRIVE, Autonomys, Antithesis Foods. These companies were founded in 2020 or later.

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