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National Science Foundation Portfolio Companies

Investor actively backing innovative startups and growth-stage companies across various industries and funding rounds.

Last updated: July 2026

National Science Foundation Investment Overview

Portfolio Companies
2,009
Total Invested
$6.8B
Average Investment
$5.9M

National Science Foundation's Most Recent Investments (2020+)

Company NameFoundedFunding StageAmountCity
Inso Biosciences2025Non-equity AssistanceUndisclosedIthaca
Allen Institute for Artificial Intelligence2025GrantUndisclosedSeattle
Lepidext2024GrantUndisclosedLexington
hominin.ai2025GrantUndisclosedSeattle
Mentium Technologies2023SeedUndisclosedSanta Barbara
The Learning Bridge2024GrantUndisclosedHadley
ZelosDx2021GrantUndisclosedTucson
Virtual Apprentice2022GrantUndisclosedRockville
Intersphere2021GrantUndisclosedFort Collins
Monogram Orthopedics2024Post-IPO EquityUndisclosedAustin

Complete List of National Science Foundation Portfolio Companies (2,009)

Export
#CompanyStageAmountLocation
76Inso BiosciencesNon-equity AssistanceUndisclosedIthaca, United States
77Allen Institute for Artificial IntelligenceGrantUndisclosedSeattle, United States
78LepidextGrantUndisclosedLexington, United States
79hominin.aiGrantUndisclosedSeattle, United States
80Mentium TechnologiesSeedUndisclosedSanta Barbara, United States
81The Learning BridgeGrantUndisclosedHadley, United States
82ZelosDxGrantUndisclosedTucson, United States
83Virtual ApprenticeGrantUndisclosedRockville, United States
84IntersphereGrantUndisclosedFort Collins, United States
85Monogram OrthopedicsPost-IPO EquityUndisclosedAustin, United States
BiotechnologyGeneticsLife Science

Inso Bio is developing automtion tools for genomic sample handling.

Ithaca, United States
August 2025
Non-equity Assistance

Founder Contacts

19,000+ verified contacts

Artificial Intelligence (AI)FinanceFinancial ServicesIncubatorsVenture Capital

Allen Institute for Artificial Intelligence (AI2) is an artificial intelligence research institute and start-up incubator.

Seattle, United States
August 2025
Grant

Founder Contacts

19,000+ verified contacts

AgricultureAgTechBiotechnologyFarming

Lepidext is engaged in managing the populations of the Lepidoptera pests by introducing bio-pesticides that are species-specific.

Lexington, United States
August 2024
Grant

Founder Contacts

19,000+ verified contacts

Artificial Intelligence (AI)Health CareRoboticsSoftware

Building the models that grow and age with you

Seattle, United States
August 2025
Grant

Founder Contacts

19,000+ verified contacts

AI InfrastructureArtificial Intelligence (AI)SaaSSemiconductor

Mentium develops co-processors for AI at the Edge, specializing in mission-critical applications, both on ground and in Space.

Santa Barbara, United States
August 2023
Seed

Founder Contacts

19,000+ verified contacts

The Learning Bridge was created on the notion that learning is a lifelong process.

Hadley, United States
August 2024
Grant

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CareLife Science

ZelosDx is a developing blood testing products to help researchers make breakthrough discoveries in brain health and disease.

Tucson, United States
August 2021
Grant

Founder Contacts

19,000+ verified contacts

TrainingVirtual Reality

Virtual Apprentice provides workforce training through virtual reality.

Rockville, United States
August 2022
Grant

Founder Contacts

19,000+ verified contacts

Digital MediaEnvironmental Consulting

Intersphere offers environmental services like weather and climate forecasts for seasonal to decadal planning horizons.

Fort Collins, United States
August 2021
Grant

Founder Contacts

19,000+ verified contacts

ManufacturingMedical DeviceRobotics

Monogram Orthopaedics is a producer of surgical robotic equipment.

Austin, United States
July 2024
Post-IPO Equity

Founder Contacts

19,000+ verified contacts

AgricultureAnimal FeedBiotechnologyChemicalFood and BeverageHealth CareTherapeutics

Bactana develops therapies for pets to treat prediabetes, diabetes and products to reduce antibiotic use during livestock production.

Farmington, United States
July 2022
Debt Financing

Founder Contacts

19,000+ verified contacts

Health CareManufacturingMedical

Agile Focus Designs provides accurate, agile, and user-friendly tools for microscopists in manufacturing, science, and healthcare.

Bozeman, United States
July 2021
Non-equity Assistance

Founder Contacts

19,000+ verified contacts

Advanced MaterialsAgricultureBeautyBiotechnologyChemical

Lygos is a Specialty Chemical Company

Berkeley, United States
July 2024
Grant

Founder Contacts

19,000+ verified contacts

Clinical TrialsCommercialMedical

O2 RegenTech is commercializing cost-effective, easy-to-use wound care solutions.

Akron, United States
July 2021
Seed

Founder Contacts

19,000+ verified contacts

ApparelE-CommerceFashionTextiles

Ambercycle is a material science company that converts textile waste into new polyester yarns for apparel brands and manufacturers.

Los Angeles, United States
July 2025
Venture - Series Unknown

Founder Contacts

19,000+ verified contacts

Clean EnergyEnergyRenewable EnergyWind Energy

Altaeros Energies develops airborne wind turbine to produce abundant, low cost, renewable energy.

Boston, United States
July 2022
Venture - Series Unknown

Founder Contacts

19,000+ verified contacts

AgricultureAgTechFarmingInternet of ThingsSoftware

Arable develops a software for agriculture that helps digitize and optimize decisions from seed breeding to food production.

San Francisco, United States
July 2022
Series C

Founder Contacts

19,000+ verified contacts

HardwareInternetWireless

Mesh++ is a wireless technology company that builds self-powered routers that run an efficient mesh networking protocol.

Chicago, United States
July 2024
Seed

Founder Contacts

19,000+ verified contacts

ElectronicsHardwareSemiconductor

Tagore Technology is a semiconductor company that manufactures radio frequency products.

Arlington Heights, United States
July 2025
Venture - Series Unknown

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CareMedicalTherapeutics

Atom Bioworks is a developer of a pattern-recognition enabled sensing and therapeutics platform designed to help in medical.

Cary, United States
July 2022
Grant

Founder Contacts

19,000+ verified contacts

AgricultureBiotechnologyManufacturingOrganic

WriggleBrew is a biotech company that produces organic fertilizers, pesticides, and soil amendments for the agriculture sector.

Orlando, United States
July 2025
Grant

Founder Contacts

19,000+ verified contacts

Health CareMedicalMedical Device

Landsdowne is a designer and maker of medical devices.

Fairfield, United States
July 2022
Grant

Founder Contacts

19,000+ verified contacts

AudioReading Apps

Charmtech Labs was founded in 2010 by a group of CS professors and Ph.D. students who wanted to make a difference in the real world.

Stony Brook, United States
July 2022
Grant

Founder Contacts

19,000+ verified contacts

BiotechnologyOrganicTest and Measurement

IngateyGen is a biotech company that concentrates on human nutrition.

Elizabeth City, United States
July 2024
Debt Financing

Founder Contacts

19,000+ verified contacts

ElectronicsLogisticsReal TimeRFIDSoftwareSupply Chain Management

Pascal Tags develops chipless identification technology to improve inventory management.

Louisville, United States
July 2023
Grant

Founder Contacts

19,000+ verified contacts

Showing 76-100 of 2,009 portfolio companies

Frequently Asked Questions About National Science Foundation

How many companies has National Science Foundation invested in?

National Science Foundation has invested in 2,009 companies tracked in our database. The portfolio spans multiple industries and funding stages, from seed-stage startups to late-stage companies.

What industries does National Science Foundation invest in?

National Science Foundation's top investment sectors include Biotechnology, Health Care, Agriculture, Medical, Artificial Intelligence (AI). The firm invests across 53 different industry categories.

What is the average investment size for National Science Foundation?

National Science Foundation's average investment size is $5.9M across its portfolio of 2,009 companies.

What are National Science Foundation's most recent investments?

Recent National Science Foundation portfolio additions include Inso Biosciences, Allen Institute for Artificial Intelligence, Lepidext, hominin.ai, Mentium Technologies. These companies were founded in 2020 or later.

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