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ARCH Venture Partners Portfolio Companies

Investor actively backing innovative startups and growth-stage companies across various industries and funding rounds.

Last updated: June 2026

ARCH Venture Partners Investment Overview

Portfolio Companies
156
Total Invested
$14.3B
Average Investment
$119.8M

ARCH Venture Partners's Most Recent Investments (2020+)

Company NameFoundedFunding StageAmountCity
Synchron2025Series D$200.0MBrooklyn
Elephas2025Series Unknown$40.0MMadison
Sonoma Biotherapeutics2025Grant$300KSouth San Francisco
Pelage Pharmaceuticals2025Series B$120.0MLos Angeles
Kardigan2025Series B$254.0MSouth San Francisco
Volastra Therapeutics2025Series A$30.1MNew York
Ollin Biosciences2025Series A$100.0MAustin
Maze Therapeutics2025Post Ipo Equity$150.0MSouth San Francisco
Rapport Therapeutics2025Post Ipo Equity$250.0MBoston
Prime Medicine2025Post Ipo Equity$5.0MCambridge

Complete List of ARCH Venture Partners Portfolio Companies (156)

Export
#CompanyStageAmountLocation
51SynchronSeries D$200.0MBrooklyn, United States
52ElephasSeries Unknown$40.0MMadison, United States
53Sonoma BiotherapeuticsGrant$300KSouth San Francisco, United States
54Pelage PharmaceuticalsSeries B$120.0MLos Angeles, United States
55KardiganSeries B$254.0MSouth San Francisco, United States
56Volastra TherapeuticsSeries A$30.1MNew York, United States
57Ollin BiosciencesSeries A$100.0MAustin, United States
58Maze TherapeuticsPost Ipo Equity$150.0MSouth San Francisco, United States
59Rapport TherapeuticsPost Ipo Equity$250.0MBoston, United States
60Prime MedicinePost Ipo Equity$5.0MCambridge, United States
Information TechnologyManufacturingMedicalMedical Device

Synchron is a bioelectronics medicine company that develops neuromodulation solutions for previously-untreatable nervous system conditions.

Brooklyn, United States
November 2025
$200.0M
Series D

Founder Contacts

19,000+ verified contacts

Artificial Intelligence (AI)BiotechnologyHealth CareHealth DiagnosticsMedical

Elephas harnesses latest advances in cancer biology, multimodal microscopy, and artificial intelligence to empower clinical decision-making.

Madison, United States
November 2025
$40.0M
Series Unknown

Founder Contacts

19,000+ verified contacts

BiotechnologyLife ScienceTherapeutics

Sonoma Biotherapeutics develops engineered regulatory T-cell (Treg) therapies to treat autoimmune and inflammatory diseases.

South San Francisco, United States
November 2025
$300K
Grant

Founder Contacts

19,000+ verified contacts

Health CareMedicalPharmaceuticalTherapeuticsWellness

Pelage Pharma is a regenerative medicine biotechnology company developing treatments for hair loss.

Los Angeles, United States
October 2025
$120.0M
Series B

Founder Contacts

19,000+ verified contacts

Artificial Intelligence (AI)BiopharmaHealth CareMedical

Kardigan develops personalized medicines using AI and data to target and treat the root causes of cardiovascular diseases.

South San Francisco, United States
October 2025
$254.0M
Series B

Founder Contacts

19,000+ verified contacts

BiotechnologyLife ScienceMedical

Volastra Therapeutics is a biotechnology company developing novel therapies for the treatment of metastatic cancers.

New York, United States
September 2025
$30.1M
Series A

Founder Contacts

19,000+ verified contacts

BiopharmaMedicalTherapeutics

Ollin Biosciences operates as a clinical-stage biopharmaceutical company.

Austin, United States
September 2025
$100.0M
Series A

Founder Contacts

19,000+ verified contacts

BiopharmaBiotechnologyGeneticsTherapeutics

Maze Therapeutics is a biotechnology company that develops precision medicines for renal, cardiovascular, and metabolic diseases.

South San Francisco, United States
September 2025
$150.0M
Post Ipo Equity

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CareLife ScienceMedicalNeurosciencePrecision Medicine

Rapport Therapeutics is a clinical-stage biotechnology company that discovers and develops precision medicines for neurological disorders.

Boston, United States
September 2025
$250.0M
Post Ipo Equity

Founder Contacts

19,000+ verified contacts

BiotechnologyGeneticsLife ScienceMedicalTherapeutics

Prime Medicine is a biotechnology company that utilizes Prime Editing to modify genetic sequences to treat a wide range of diseases.

Cambridge, United States
August 2025
$5.0M
Post Ipo Equity

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CareMedicalPharmaceutical

Lyell Immunopharma is an operator of a biotechnology company that develops cellular therapies to cure cancer.

South San Francisco, United States
July 2025
$100.0M
Post Ipo Equity

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CareTherapeutics

Dispatch Biotherapeutics develops immunotherapy that treats solid tumors, which could significantly advance cancer treatment options.

Philadelphia, United States
July 2025
$216.0M
Series A

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CareMedicalPharmaceutical

CStone Pharmaceuticals is a bio-pharmaceutical company develops new treatments in a range of therapeutic areas.

Suzhou, China
July 2025
$59.7M
Post Ipo Equity

Founder Contacts

19,000+ verified contacts

BiotechnologyLife SciencePharmaceuticalTherapeutics

CERo Therapeutics, Inc. is a new cellular immunotherapy company.

South San Francisco, United States
April 2025
$8.0M
Post Ipo Equity

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CareMedical

AIRNA develops RNA editing technologies to create medicines for various diseases.

Cambridge, United States
April 2025
$155.0M
Series B

Founder Contacts

19,000+ verified contacts

Artificial Intelligence (AI)BiopharmaBiotechnologyLife Science

Arbor Biotechnologies is a biotechnology company specializing in next-generation gene editing therapeutics to treat genetic diseases.

Cambridge, United States
March 2025
$73.9M
Series C

Founder Contacts

19,000+ verified contacts

BiotechnologyGeneticsHealth DiagnosticsOncologyPharmaceutical

Genetix Biotherapeutics develops and delivers approved gene therapies for severe rare genetic diseases like sickle cell.

Somerville, United States
February 2025
Private Equity

Founder Contacts

19,000+ verified contacts

Artificial Intelligence (AI)Health CareHospital

Homeward is focused on improving access to high-quality, affordable primary and specialty care in rural communities.

San Francisco, United States
February 2025
$12.0M
Grant

Founder Contacts

19,000+ verified contacts

BiopharmaBiotechnologyPharmaceutical

Be Biopharma develops engineered B cell medicines for serious genetic diseases.

Cambridge, United States
January 2025
$92.0M
Series C

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CareTherapeutics

Rhygaze develops a novel gene therapy that targets cone cells to restore vision in patients suffering from diseases causing blindness.

Basel, Switzerland
January 2025
$86.0M
Series A

Founder Contacts

19,000+ verified contacts

BiotechnologyMedicalNeuroscienceTherapeutics

Tenvie Therapeutics is a biotechnology company that transforms the treatment of neurological diseases through engineered small molecules.

South San Francisco, United States
January 2025
$200.0M
Series A

Founder Contacts

19,000+ verified contacts

BiopharmaBiotechnologyMedicalPharmaceutical

Soufflé Therapeutics has potent, precise, and safe medicines can be designed and developed for all diseases.

Watertown, United States
January 2025
$200.0M
Series A

Founder Contacts

19,000+ verified contacts

Artificial Intelligence (AI)BiotechnologyHealth CareMedicalProduct Research

Generate Biomedicines is a biotech company that combines biology, machine learning, and biological engineering to create biomedicines.

Somerville, United States
December 2024
Series Unknown

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CareOncologyTherapeutics

Akamis Bio is a clinical-stage oncology company.

Abingdon, United Kingdom
December 2024
$60.0M
Series A

Founder Contacts

19,000+ verified contacts

BiopharmaHealth CareMedicalPharmaceutical

Metsera is a clinical‐stage biotech firm developing oral & injectable hormone therapies to treat obesity & related metabolic diseases.

New York, United States
November 2024
$215.0M
Series B

Founder Contacts

19,000+ verified contacts

Showing 51-75 of 156 portfolio companies

Frequently Asked Questions About ARCH Venture Partners

How many companies has ARCH Venture Partners invested in?

ARCH Venture Partners has invested in 156 companies tracked in our database. The portfolio spans multiple industries and funding stages, from seed-stage startups to late-stage companies.

What industries does ARCH Venture Partners invest in?

ARCH Venture Partners's top investment sectors include Biotechnology, Medical, Health Care, Therapeutics, Pharmaceutical. The firm invests across 19 different industry categories.

What is ARCH Venture Partners's largest investment?

Among tracked funding rounds, Kardigan received $254.0M in a Series B round. ARCH Venture Partners's total known invested capital is $14.3B.

What is the average investment size for ARCH Venture Partners?

ARCH Venture Partners's average investment size is $119.8M across its portfolio of 156 companies.

What are ARCH Venture Partners's most recent investments?

Recent ARCH Venture Partners portfolio additions include Synchron, Elephas, Sonoma Biotherapeutics, Pelage Pharmaceuticals, Kardigan. These companies were founded in 2020 or later.

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