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ARCH Venture Partners Portfolio Companies

Investor actively backing innovative startups and growth-stage companies across various industries and funding rounds.

Last updated: June 2026

ARCH Venture Partners Investment Overview

Portfolio Companies
156
Total Invested
$14.3B
Average Investment
$119.8M

ARCH Venture Partners's Most Recent Investments (2020+)

Company NameFoundedFunding StageAmountCity
Gossamer Bio2023Post Ipo Equity$212.0MSan Diego
Mozart Therapeutics2023Series A$25.0MSeattle
Bitterroot Bio2023Series A$145.0MPalo Alto
OncoResponse2023Series D$14.0MSeattle
CREATE Medicines2023Series A$73.0MCambridge
Boundless Bio2023Series C$100.0MLa Jolla
Orbital Therapeutics2023Series A$270.0MCambridge
Recuro Health2023Series B$47.0MRichardson
Paratus Sciences2023Series A$100.0MNew York
Aera Therapeutics2023Series B$193.0MBoston

Complete List of ARCH Venture Partners Portfolio Companies (156)

Export
#CompanyStageAmountLocation
101Gossamer BioPost Ipo Equity$212.0MSan Diego, United States
102Mozart TherapeuticsSeries A$25.0MSeattle, United States
103Bitterroot BioSeries A$145.0MPalo Alto, United States
104OncoResponseSeries D$14.0MSeattle, United States
105CREATE MedicinesSeries A$73.0MCambridge, United States
106Boundless BioSeries C$100.0MLa Jolla, United States
107Orbital TherapeuticsSeries A$270.0MCambridge, United States
108Recuro HealthSeries B$47.0MRichardson, United States
109Paratus SciencesSeries A$100.0MNew York, United States
110Aera TherapeuticsSeries B$193.0MBoston, United States
BiotechnologyHealth CareTherapeutics

Gossamer Bio is a biopharmaceutical company focused on the discovery and development of novel and differentiated therapeutic products.

San Diego, United States
July 2023
$212.0M
Post Ipo Equity

Founder Contacts

19,000+ verified contacts

Biotechnology

Mozart is a biotech startup focusing on the development of disease-modifying therapies for autoimmune and inflammatory diseases.

Seattle, United States
June 2023
$25.0M
Series A

Founder Contacts

19,000+ verified contacts

BiotechnologyEmergency MedicineMedical

Bitterroot Bio leverages the power of immunotherapy to develop and deliver novel medicines for cardiovascular disease.

Palo Alto, United States
June 2023
$145.0M
Series A

Founder Contacts

19,000+ verified contacts

BiopharmaBiotechnologyHealth CareOncologyTherapeutics

OncoResponse is an immuno-oncology biotech company developing cancer immunotherapies leveraging human immune system responses.

Seattle, United States
May 2023
$14.0M
Series D

Founder Contacts

19,000+ verified contacts

BiotechnologyLife ScienceTherapeutics

CREATE Medicines is a clinical stage mRNA-immunotherapy company developing novel therapies for cancer and autoimmune diseases.

Cambridge, United States
May 2023
$73.0M
Series A

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CareLife ScienceOncologyTherapeutics

Boundless Bio is a precision oncology company that develops therapeutics directed against extrachromosomal DNA in aggressive cancers.

La Jolla, United States
May 2023
$100.0M
Series C

Founder Contacts

19,000+ verified contacts

Alternative MedicineBiotechnologyLife ScienceTherapeutics

Orbital Therapeutics is a biotechnology company that develops RNA-based medicines to treat disease in humans.

Cambridge, United States
April 2023
$270.0M
Series A

Founder Contacts

19,000+ verified contacts

Health CareHospitalOutpatient Care

Recuro Health offers a holistic suite of virtual care services and supplemental benefits.

Richardson, United States
April 2023
$47.0M
Series B

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth Care

Paratus Sciences is dedicated to advancing human health and health security by comprehending the biology of bats.

New York, United States
February 2023
$100.0M
Series A

Founder Contacts

19,000+ verified contacts

BiopharmaBiotechnologyProduct Research

Aera Therapeutics is a biotechnology firm that employs its own protein nanoparticle (PNP) delivery platform.

Boston, United States
February 2023
$193.0M
Series B

Founder Contacts

19,000+ verified contacts

BiopharmaBiotechnologyGenetics

Protillion Biosciences specializes in the design and development of protein-based drugs.

Burlingame, United States
December 2022
$18.0M
Series A

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CarePharmaceuticalTherapeutics

Carrick Therapeutics is a developer of cancer therapeutics intended to transform the way cancer is treated.

Dublin, Ireland
December 2022
$60.0M
Series C

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CareLife Science

HC Bioscience is an innovator and pioneer of protein editing using context agnostic engineered tRNA.

Cambridge, United States
November 2022
$16.0M
Series A

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CareTherapeutics

Excision is developing CRISPR-based therapies to cure viral infectious diseases and improve the lives of chronically ill patients.

Philadelphia, United States
September 2022
$6.8M
Grant

Founder Contacts

19,000+ verified contacts

Health CareMental HealthmHealthPersonal HealthTherapeuticsWellness

Mindstrong is a virtual mental health platform.

Menlo Park, United States
September 2022
$250K
Grant

Founder Contacts

19,000+ verified contacts

BiotechnologyMedicalTherapeutics

Codiak is a clinical-stage biopharmaceutical company focused on pioneering the development of exosome-based therapeutics.

San Francisco, United States
September 2022
$20.0M
Post Ipo Equity

Founder Contacts

19,000+ verified contacts

Health Care

Happy Health is a mission-driven technology company

Austin, United States
August 2022
$60.0M
Series A

Founder Contacts

19,000+ verified contacts

BiotechnologyLife ScienceTherapeutics

Pheast Therapeutics develops checkpoint therapies to harness the innate immune system.

Palo Alto, United States
April 2022
$76.0M
Series A

Founder Contacts

19,000+ verified contacts

AppsHealth CareHealth DiagnosticsLife ScienceMobile AppsProduct Management

Proof Diagnostics is a health technology company that develops a diagnostic test for the detection of coronavirus disease infection.

Cambridge, United States
April 2022
$45.0M
Series A

Founder Contacts

19,000+ verified contacts

BiotechnologyGeneticsProduct Research

Jaguar Gene Therapy is accelerating breakthroughs in gene therapy for patients suffering from severe genetic diseases.

Lake Forest, United States
March 2022
Series Unknown

Founder Contacts

19,000+ verified contacts

FitnessHealth CareWellness

Feelmore Labs is an innovative health & wellness technology company.

Brooklyn, United States
March 2022
$4.0M
Debt Financing

Founder Contacts

19,000+ verified contacts

B2BBiotechnologyChemicalHealth CareLife Science

Twist Bioscience is a biotechnology company that offers synthetic DNA solutions, gene synthesis, and variant libraries.

San Francisco, United States
February 2022
$250.0M
Post Ipo Equity

Founder Contacts

19,000+ verified contacts

BiopharmaBiotechnology

Transcenta is a global biotherapeutic company that fully integrates antibody-based biotherapeutics discovery, R&D and manufacture.

Huangpu, China
November 2021
Post Ipo Equity

Founder Contacts

19,000+ verified contacts

BatteryChemicalHardwareManufacturing

908devices manufactures battery-operated, hand-held chemical detection tools used in mass spectrometry.

Boston, United States
November 2021
$101.0M
Post Ipo Equity

Founder Contacts

19,000+ verified contacts

Biotechnology

Singleron Biotechnologies is an innovative molecular diagnostic company.

Nanjing, China
November 2021
$100.0M
Series B

Founder Contacts

19,000+ verified contacts

Showing 101-125 of 156 portfolio companies

Frequently Asked Questions About ARCH Venture Partners

How many companies has ARCH Venture Partners invested in?

ARCH Venture Partners has invested in 156 companies tracked in our database. The portfolio spans multiple industries and funding stages, from seed-stage startups to late-stage companies.

What industries does ARCH Venture Partners invest in?

ARCH Venture Partners's top investment sectors include Biotechnology, Health Care, Therapeutics, Life Science, Biopharma. The firm invests across 28 different industry categories.

What is ARCH Venture Partners's largest investment?

Among tracked funding rounds, Orbital Therapeutics received $270.0M in a Series A round. ARCH Venture Partners's total known invested capital is $14.3B.

What is the average investment size for ARCH Venture Partners?

ARCH Venture Partners's average investment size is $119.8M across its portfolio of 156 companies.

What are ARCH Venture Partners's most recent investments?

Recent ARCH Venture Partners portfolio additions include Gossamer Bio, Mozart Therapeutics, Bitterroot Bio, OncoResponse, CREATE Medicines. These companies were founded in 2020 or later.

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