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MassChallenge Portfolio Companies

Investor actively backing innovative startups and growth-stage companies across various industries and funding rounds.

Last updated: June 2026

MassChallenge Investment Overview

Portfolio Companies
807
Total Invested
$3.4B
Average Investment
$6.6M

MassChallenge's Most Recent Investments (2020+)

Company NameFoundedFunding StageAmountCity
Kismet Technologies2023Seed$5.0MOrlando
BoxMagic2023Seed$100KCharlotte
Meetcaregivers2023Venture - Series Unknown$2.2MNewton
DrizzleX2023Seed$2.3MMontebello
Luminopia2023Series A$16.0MCambridge
CareAcademy2023Venture - Series UnknownUndisclosedCambridge
Alkeus Pharmaceuticals2023Series B$150.0MCambridge
Fortify2023Venture - Series Unknown$12.5MBoston
Ronawk2023Series A$6.5MOlathe
BeeReaders2023Seed$3.5MAustin

Complete List of MassChallenge Portfolio Companies (807)

Export
#CompanyStageAmountLocation
126Kismet TechnologiesSeed$5.0MOrlando, United States
127BoxMagicSeed$100KCharlotte, United States
128MeetcaregiversVenture - Series Unknown$2.2MNewton, United States
129DrizzleXSeed$2.3MMontebello, United States
130LuminopiaSeries A$16.0MCambridge, United States
131CareAcademyVenture - Series UnknownUndisclosedCambridge, United States
132Alkeus PharmaceuticalsSeries B$150.0MCambridge, United States
133FortifyVenture - Series Unknown$12.5MBoston, United States
134RonawkSeries A$6.5MOlathe, United States
135BeeReadersSeed$3.5MAustin, United States
Health CareMedicalWellness

Kismet Technologies delivers innovative material technologies for safe infection control on surfaces.

Orlando, United States
August 2023
$5.0M
Seed

Founder Contacts

19,000+ verified contacts

E-CommerceFitnessInformation TechnologyPersonal HealthSoftwareSports

BoxMagic is a mobile app helping gym owners to run their day to day operations.

Charlotte, United States
July 2023
$100K
Seed

Founder Contacts

19,000+ verified contacts

Elder CareElderlyHealth CareInformation Technology

Meetcaregivers is a marketplace for senior care, intelligently matching seniors with perfect caregivers, more services, products and tools.

Newton, United States
July 2023
$2.2M
Venture - Series Unknown

Founder Contacts

19,000+ verified contacts

AnalyticsBig DataInternet of ThingsProperty ManagementPropTechSaaSSocial ImpactWater

Solving the last mile problem of water waste in apartment buildings

Montebello, United States
July 2023
$2.3M
Seed

Founder Contacts

19,000+ verified contacts

Health CareMedicalVirtual Reality

Luminopia develops a new class of treatments for significant neuro-visual disorders.

Cambridge, United States
June 2023
$16.0M
Series A

Founder Contacts

19,000+ verified contacts

EducationHealth CareHome Health CareSaaSTraining

CareAcademy offers an online training empowering senior care professionals to deliver the highest caliber of services.

Cambridge, United States
June 2023
Venture - Series Unknown

Founder Contacts

19,000+ verified contacts

BiotechnologyMedicalMedical DevicePharmaceutical

Alkeus Pharmaceuticals is a Boston-based startup focused on treatments for serious ophthalmic conditions.

Cambridge, United States
June 2023
$150.0M
Series B

Founder Contacts

19,000+ verified contacts

3D Printing3D TechnologyIndustrial EngineeringManufacturingMechanical Engineering

Fortify is a digital composite manufacturing startup that is transforming the 3D printing industry.

Boston, United States
June 2023
$12.5M
Venture - Series Unknown

Founder Contacts

19,000+ verified contacts

BiopharmaBiotechnologyHealth Care

Ronawk develops a T-Block technology producing patient-specific biologics to treat diseases, cancer, organ injuries, and burns.

Olathe, United States
May 2023
$6.5M
Series A

Founder Contacts

19,000+ verified contacts

EdTechEducationLanguage Learning

Edtech company delivering digital solutions for PreK-12 Spanish literacy improvement

Austin, United States
April 2023
$3.5M
Seed

Founder Contacts

19,000+ verified contacts

Health CareHospitalMedicalMedical Device

1upHealth is a healthcare data platform operator that aggregates and shares medical data for patients, providers, and software developers.

Boston, United States
April 2023
$40.0M
Series C

Founder Contacts

19,000+ verified contacts

AnalyticsBig DataDatabaseDeveloper ToolsInformation TechnologyTechnical Support

IT company with 20 years of experience developing database management tools

New City, United States
April 2023
$6.0M
Seed

Founder Contacts

19,000+ verified contacts

Health Care

Relavo offers a device to prevent infection in peritoneal dialysis, a form of at-home treatment for end-stage renal disease.

Baltimore, United States
April 2023
$500K
Seed

Founder Contacts

19,000+ verified contacts

SaaSWeb AppsWeb DesignWeb Development

Equalize Digital is a Certified B Corporation that specializes in web accessibility products and consulting.

Georgetown, United States
March 2023
$300K
Seed

Founder Contacts

19,000+ verified contacts

Advanced MaterialsInformation TechnologyNanotechnology

Graphene Composites is a nano-technology startup that combines graphene with aerogel .

Bincombe, United Kingdom
March 2023
$1.1M
Seed

Founder Contacts

19,000+ verified contacts

Consumer ElectronicsHealth CareParentingPersonal HealthWearables

Lilu is a women's health company building tech-enabled devices to empower new moms.

New York, United States
March 2023
$1.0M
Seed

Founder Contacts

19,000+ verified contacts

AppsArtificial Intelligence (AI)Health CareMedical DevicemHealth

Care Angel is a Consumer engagement Platform leveraging AI to improve patient outcomes, enable clinical worker, and operational efficiency.

Miami, United States
March 2023
$6.9M
Venture - Series Unknown

Founder Contacts

19,000+ verified contacts

AppsEventsSports

CrowdPlay develops a fan engagement platform to engage with live sporting events.

Boston, United States
March 2023
$1.9M
Seed

Founder Contacts

19,000+ verified contacts

Biotechnology

Tellus Therapeutics develops novel small molecules derived from human maternal breast milk.

Hillsborough, United States
February 2023
$16.0M
Venture - Series Unknown

Founder Contacts

19,000+ verified contacts

Health CareMedicalMedical Device

InnoVein develops a medical device designed to offer implants for valve replacement in the femoral vein.

San Carlos, United States
February 2023
$2.5M
Venture - Series Unknown

Founder Contacts

19,000+ verified contacts

AgricultureAgTechBiotechnologyCleanTechFarming

Entocycle develops the technology to enable efficient and scalable insect farming.

London, United Kingdom
January 2023
$5.0M
Series A

Founder Contacts

19,000+ verified contacts

HardwareHospitalityLaundry and Dry-cleaning

Presso offers distributed micro-retail solution for ultra-fast dry-cleaning.

Atlanta, United States
January 2023
$8.0M
Seed

Founder Contacts

19,000+ verified contacts

Health CareWellnessWomen's

Milkify offers freeze- dry breast milk for longer storage, more convenience, and better infant nutrition.

Houston, United States
January 2026
$3.7M
Venture - Series Unknown

Founder Contacts

19,000+ verified contacts

BioinformaticsBiopharmaBiotechnologyHealth Care

Octarine Bio is a synthetic biology company that produces superior cannabinoids for the pharmaceutical industry.

Copenhagen, Denmark
January 2026
$5.9M
Series A

Founder Contacts

19,000+ verified contacts

AnalyticsArtificial Intelligence (AI)BiotechnologyMedical DeviceSoftware

Biometry is a health technology company that develops diagnostic tools to support patients with chronic respiratory conditions.

Boston, United States
December 2025
$2.2M
Seed

Founder Contacts

19,000+ verified contacts

Showing 126-150 of 807 portfolio companies

Frequently Asked Questions About MassChallenge

How many companies has MassChallenge invested in?

MassChallenge has invested in 807 companies tracked in our database. The portfolio spans multiple industries and funding stages, from seed-stage startups to late-stage companies.

What industries does MassChallenge invest in?

MassChallenge's top investment sectors include Health Care, Biotechnology, Medical, Medical Device, Information Technology. The firm invests across 59 different industry categories.

What is MassChallenge's largest investment?

Among tracked funding rounds, Alkeus Pharmaceuticals received $150.0M in a Series B round. MassChallenge's total known invested capital is $3.4B.

What is the average investment size for MassChallenge?

MassChallenge's average investment size is $6.6M across its portfolio of 807 companies.

What are MassChallenge's most recent investments?

Recent MassChallenge portfolio additions include Kismet Technologies, BoxMagic, Meetcaregivers, DrizzleX, Luminopia. These companies were founded in 2020 or later.

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