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MassChallenge Portfolio Companies

Investor actively backing innovative startups and growth-stage companies across various industries and funding rounds.

Last updated: June 2026

MassChallenge Investment Overview

Portfolio Companies
807
Total Invested
$3.4B
Average Investment
$6.6M

MassChallenge's Most Recent Investments (2020+)

Company NameFoundedFunding StageAmountCity
LambdaVision2025Seed$7.0MFarmington
MyoGene Bio2025Venture - Series Unknown$400KLos Angeles
Clean Crop Technologies2025Venture - Series Unknown$7.9MHolyoke
The Blue Box Biomedical Solutions2025Seed$3.5MBarcelona
AgZen2026Series B$10.0MSomerville
Amulet2026Debt Financing$758KMadison
Malama Health2026Seed$6.9MStanford
Cyclops.io2026Seed$8.0MCambridge
Clean Valley Bio-filtration Technologies2026Debt Financing$4.0MDartmouth
Shearwater Aerospace2026Seed$3.0MMontréal

Complete List of MassChallenge Portfolio Companies (807)

Export
#CompanyStageAmountLocation
151LambdaVisionSeed$7.0MFarmington, United States
152MyoGene BioVenture - Series Unknown$400KLos Angeles, United States
153Clean Crop TechnologiesVenture - Series Unknown$7.9MHolyoke, United States
154The Blue Box Biomedical SolutionsSeed$3.5MBarcelona, Spain
155AgZenSeries B$10.0MSomerville, United States
156AmuletDebt Financing$758KMadison, United States
157Malama HealthSeed$6.9MStanford, United States
158Cyclops.ioSeed$8.0MCambridge, United States
159Clean Valley Bio-filtration TechnologiesDebt Financing$4.0MDartmouth, Canada
160Shearwater AerospaceSeed$3.0MMontréal, Canada
AerospaceBiotechnologyHealth CareMedical

LambdaVision is a biotechnology company that develops a protein-based artificial retina to restore vision for patients.

Farmington, United States
November 2025
$7.0M
Seed

Founder Contacts

19,000+ verified contacts

BiotechnologyGeneticsHealth CareTherapeuticsWellness

MyoGene Bio develops therapies for muscle diseases, starting with a gene-editing therapy for Duchenne muscular dystrophy.

Los Angeles, United States
November 2025
$400K
Venture - Series Unknown

Founder Contacts

19,000+ verified contacts

AgTechCleanTechFarmingFood ProcessingQuality AssuranceWaste Management

Clean Crop Technologies specializes in advanced treatments for foods and seeds, effectively reducing mold, pathogens, and bacteria.

Holyoke, United States
November 2025
$7.9M
Venture - Series Unknown

Founder Contacts

19,000+ verified contacts

Artificial Intelligence (AI)Health CareInternet of ThingsMedical Device

The Blue Box is a medical equipment manufacturing firm developing radiation and pain free breast cancer urine test.

Barcelona, Spain
November 2025
$3.5M
Seed

Founder Contacts

19,000+ verified contacts

AgricultureAgTechFarming

AgZen develops pesticide sprays stick to plants which reduces pollution and helps farmers save.

Somerville, United States
March 2026
$10.0M
Series B

Founder Contacts

19,000+ verified contacts

Health CareHealth DiagnosticsMobile AppsPersonal HealthSensor

Amulet provides consumer food allergen sensors that helps in testing for common allergenic ingredients in seconds.

Madison, United States
March 2026
$758K
Debt Financing

Founder Contacts

19,000+ verified contacts

Health CareHome Health CareMedicalSoftwareWomen's

Malama offers holistic support through community-based doulas, covering various services like pregnancy care and postpartum recovery.

Stanford, United States
March 2026
$6.9M
Seed

Founder Contacts

19,000+ verified contacts

Information TechnologyInternetSoftware

Cyclops.io is a new operating system for team collaboration.

Cambridge, United States
March 2026
$8.0M
Seed

Founder Contacts

19,000+ verified contacts

AgTechAquacultureRenewable Energy

Clean Valley CIC is a group of entrepreneurs, engineers and environmental scientists with a nature-inspired ideas for Canadian Innovation.

Dartmouth, Canada
March 2026
$4.0M
Debt Financing

Founder Contacts

19,000+ verified contacts

Artificial Intelligence (AI)Machine LearningSoftware

Shearwater Aerospace is a software company that uses AI and reinforcement learning in order to enable fixed-wing drones by using wind energy

Montréal, Canada
February 2026
$3.0M
Seed

Founder Contacts

19,000+ verified contacts

Artificial Intelligence (AI)RoboticsSoftware

Breaker develops cutting-edge software that transforms the interaction between humans and machines.

Austin, United States
February 2026
$6.4M
Seed

Founder Contacts

19,000+ verified contacts

Analytics

Apeiron labs mission is to provide data from the upper of the ocean.

Cambridge, United States
February 2026
$9.5M
Series A

Founder Contacts

19,000+ verified contacts

AgTechAquacultureComputerFood and BeverageSeafood

BlueTrace offers a traceability solution for shellfish growers, wholesalers, distributors, and dealers.

Castine, United States
February 2026
$1.3M
Seed

Founder Contacts

19,000+ verified contacts

BiometricsBiotechnologyHealth Care

Imbed Biosciences is a Privately held medical device company.

Fitchburg, United States
January 2026
Corporate Round

Founder Contacts

19,000+ verified contacts

BioinformaticsBiopharmaBiotechnologyHealth Care

Octarine Bio is a synthetic biology company that produces superior cannabinoids for the pharmaceutical industry.

Copenhagen, Denmark
January 2026
$5.9M
Series A

Founder Contacts

19,000+ verified contacts

Environmental EngineeringWater Purification

NALA Membranes provides environmental services with an intention to bring new reverse osmosis membranes.

Morrisville, United States
January 2026
$10.8M
Seed

Founder Contacts

19,000+ verified contacts

MedicalMedical Device

Babylat is an enricher device is the first automated, small-scale tabletop device for the protein enrichment of human milk.

Bern, Switzerland
January 2026
$1.0M
Grant

Founder Contacts

19,000+ verified contacts

BiotechnologyPackaging ServicesWater

Noriware is a packaging materials manufacturing company that offers seaweed-based packaging film composed of natural materials.

Brugg, Switzerland
January 2026
$5.0M
Seed

Founder Contacts

19,000+ verified contacts

3D PrintingBiotechnologyMedical Device

Nanochon develops medical implant technology focused on cartilage repair for patients with joint surface damage.

Washington, United States
January 2026
$4.1M
Seed

Founder Contacts

19,000+ verified contacts

Artificial Intelligence (AI)Data Center AutomationMachine Learning

DeepSee.ai provides AI-powered automation solutions for knowledge-driven decision-making.

Draper, United States
January 2026
Corporate Round

Founder Contacts

19,000+ verified contacts

Health CareWellnessWomen's

Milkify offers freeze- dry breast milk for longer storage, more convenience, and better infant nutrition.

Houston, United States
January 2026
$3.7M
Series Unknown

Founder Contacts

19,000+ verified contacts

Information TechnologyService IndustryTravel

StreetScan is a company that provides up-to-date, accurate, and cost efficient information on road conditions.

Montréal, Canada
January 2026
Series Unknown

Founder Contacts

19,000+ verified contacts

BiotechnologyEducationElectronicsHardwareNeuroscience

BrainCo develops brain-computer interface technologies for wellness and education applications.

Somerville, United States
January 2026
$286.4M
Series Unknown

Founder Contacts

19,000+ verified contacts

BiotechnologyLife ScienceMarketplace

iSpecimen is the marketplace for human biospecimens, providing researchers with the samples they need from the patients they want.

Lexington, United States
December 2025
$5.5M
Post Ipo Equity

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CareManufacturingMedical DeviceNeuroscience

CranioSense is bringing intracranial hypertension into the light by simplifying the diagnostic process across the clinical spectrum.

Bedford, United States
December 2025
$5.5M
Grant

Founder Contacts

19,000+ verified contacts

Showing 151-175 of 807 portfolio companies

Frequently Asked Questions About MassChallenge

How many companies has MassChallenge invested in?

MassChallenge has invested in 807 companies tracked in our database. The portfolio spans multiple industries and funding stages, from seed-stage startups to late-stage companies.

What industries does MassChallenge invest in?

MassChallenge's top investment sectors include Biotechnology, Health Care, AgTech, Artificial Intelligence (AI), Medical Device. The firm invests across 52 different industry categories.

What is MassChallenge's largest investment?

Among tracked funding rounds, BrainCo received $286.4M in a Series Unknown round. MassChallenge's total known invested capital is $3.4B.

What is the average investment size for MassChallenge?

MassChallenge's average investment size is $6.6M across its portfolio of 807 companies.

What are MassChallenge's most recent investments?

Recent MassChallenge portfolio additions include LambdaVision, MyoGene Bio, Clean Crop Technologies, The Blue Box Biomedical Solutions, AgZen. These companies were founded in 2020 or later.

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