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OrbiMed Portfolio Companies

Investor actively backing innovative startups and growth-stage companies across various industries and funding rounds.

Last updated: July 2026

OrbiMed Investment Overview

Portfolio Companies
239
Total Invested
$12.2B
Average Investment
$87.5M

OrbiMed's Most Recent Investments (2020+)

Company NameFoundedFunding StageAmountCity
ImageneBio2026Post-IPO EquityUndisclosedSan Diego
Sionna Therapeutics2024Series CUndisclosedNatick
Apollomics2026Post-IPO DebtUndisclosedFoster City
Lomond Therapeutics2025Venture - Series UnknownUndisclosedSan Diego
Pinnacle Medicines2026Series BUndisclosedDoylestown
Nkarta Therapeutics2024Post-IPO EquityUndisclosedSouth San Francisco
Capstan Therapeutics2024Series BUndisclosedSan Diego
Harvest Integrated Research Organization2022Series AUndisclosedExcelsior
QuantX Biosciences2026Series BUndisclosedPrinceton
Tyra Biosciences2024Post-IPO EquityUndisclosedCarlsbad

Complete List of OrbiMed Portfolio Companies (239)

Export
#CompanyStageAmountLocation
26ImageneBioPost-IPO EquityUndisclosedSan Diego, United States
27Sionna TherapeuticsSeries CUndisclosedNatick, United States
28ApollomicsPost-IPO DebtUndisclosedFoster City, United States
29Lomond TherapeuticsVenture - Series UnknownUndisclosedSan Diego, United States
30Pinnacle MedicinesSeries BUndisclosedDoylestown, United States
31Nkarta TherapeuticsPost-IPO EquityUndisclosedSouth San Francisco, United States
32Capstan TherapeuticsSeries BUndisclosedSan Diego, United States
33Harvest Integrated Research OrganizationSeries AUndisclosedExcelsior, United States
34QuantX BiosciencesSeries BUndisclosedPrinceton, United States
35Tyra BiosciencesPost-IPO EquityUndisclosedCarlsbad, United States
BiopharmaBiotechnologyHealth Care

ImageneBio is dedicated to developing therapeutics for patients with immunological, autoimmune and inflammatory diseases

San Diego, United States
April 2026
Post-IPO Equity

Founder Contacts

19,000+ verified contacts

BiotechnologyGeneticsHealth CareMedicalPharmaceuticalTherapeutics

Sionna Therapeutics is developing novel small molecule therapies to treat cystic fibrosis (CF).

Natick, United States
March 2024
Series C

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CareOncologyPharmaceutical

Apollomics is a biopharmaceutical company discovering and developing mono- and combination- oncology therapies to harness the immune system.

Foster City, United States
March 2026
Post-IPO Debt

Founder Contacts

19,000+ verified contacts

BiopharmaBiotechnologyHealth CareMedical

Lomond Therapeutics creates pharmacological platforms that target escape mutations.

San Diego, United States
March 2025
Venture - Series Unknown

Founder Contacts

19,000+ verified contacts

BiopharmaBiotechnologyMedicalTherapeutics

Pinnacle Medicines is a peptide drug discovery company that provides peptide modality for medical needs.

Doylestown, United States
March 2026
Series B

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth Care

Nkarta Therapeutics is a developer of cell engineering platform created to build the next generation of cell therapies.

South San Francisco, United States
March 2024
Post-IPO Equity

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CareMedicalTherapeutics

Capstan Therapeutics develops in vivo mRNA and gene-editing medicines for a broad range of diseases.

San Diego, United States
March 2024
Series B

Founder Contacts

19,000+ verified contacts

BiopharmaBiotechnologyClinical TrialsMedicalPharmaceutical

Harvest Integrated Research Organization (HiRO) is a globally oriented, innovative clinical research organization (CRO).

Excelsior, United States
March 2022
Series A

Founder Contacts

19,000+ verified contacts

BiotechnologyPharmaceuticalTherapeutics

QuantX Biosciences is a biotechnology company that specializes in computational drug discovery and small-molecule therapeutic products.

Princeton, United States
February 2026
Series B

Founder Contacts

19,000+ verified contacts

BiotechnologyLife ScienceOncologyTherapeutics

Tyra Biosciences is a biotechnology company targeting new pathways of acquired resistance in oncology with purpose-built drugs.

Carlsbad, United States
February 2024
Post-IPO Equity

Founder Contacts

19,000+ verified contacts

Health CareMedicalTherapeutics

Star Therapeutics mission is to develop therapies for as many diseases as possible for millions of patients.

South San Francisco, United States
September 2025
$125.0M
Series D

Founder Contacts

19,000+ verified contacts

BiopharmaBiotechnologyPharmaceuticalTherapeutics

Sparrow Pharmaceuticals is a clinical-stage biopharmaceutical company developing treatments for disorders of corticosteroid excess.

Portland, United States
September 2025
$95.0M
Series B

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CareMedicalOncologyTherapeutics

Avenzo Therapeutics specializes in the development of oncology therapies for cancer treatment.

San Diego, United States
September 2025
$60.0M
Series B

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CareLife ScienceMedicalPrecision Medicine

Treeline Biosciences is a biotech company building transformative precision medicines for patients with cancer and other serious conditions.

Watertown, United States
September 2025
$200.0M
Series A

Founder Contacts

19,000+ verified contacts

MedicalTherapeutics

Leal Therapeutics develops novel therapeutics for patients.

Worcester, United States
August 2025
$30.0M
Series A

Founder Contacts

19,000+ verified contacts

Health CareMedical Device

ProVerum Medical is a medtech company that develops novel minimally invasive devices to treat benign prostatic hyperplasia.

Dublin, Ireland
August 2025
$80.0M
Series B

Founder Contacts

19,000+ verified contacts

BiopharmaBiotechnologyMedical

ENYO Pharma is a biopharmaceutical company based in Lyon, France.

Lyon, France
June 2025
$6.9M
Series C

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CareHealth DiagnosticsMedical

Alpheus Medical provides a novel sonodynamic therapy platform targeting solid body cancers.

Oakdale, United States
May 2025
$52.0M
Series B

Founder Contacts

19,000+ verified contacts

BiotechnologyMedical

RayThera is dedicated to developing small molecule therapies specifically targeting unmet needs in immunology.

San Diego, United States
April 2025
$110.0M
Series A

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CareLife ScienceTherapeutics

Garuda Therapeutics develops off-the-shelf hematopoietic stem cell therapies to treat severe and life-threatening diseases.

Cambridge, United States
March 2025
$50.0M
Series A

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CareMedicalTherapeutics

Aer Therapeutics, a clinical-stage biopharmaceutical company developing therapeutic solutions for muco-obstructive lung diseases.

Raleigh, United States
February 2025
$5.0M
Venture - Series Unknown

Founder Contacts

19,000+ verified contacts

BiopharmaBiotechnologyHealth CareMedicalTherapeutics

Helicore Biopharma is a biopharmaceutical company that discovers and develops novel weight-loss therapeutics.

San Mateo, United States
January 2025
$65.0M
Series A

Founder Contacts

19,000+ verified contacts

Health CareMedicalPharmaceutical

Convergent Therapeutics is a pharmaceutical company that focuses on developing radiopharmaceutical therapies for prostate cancer.

Cambridge, United States
September 2024
$40.0M
Series A

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CareTherapeutics

MBX Biosciences is a preclinical-stage biotech company that creates therapies to treat rare endocrine diseases.

Carmel, United States
August 2024
$63.5M
Series C

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CareMedical

Vanqua Bio is a biotechnology company that discovers and develops next-generation medicines for patients with neurodegenerative diseases.

Chicago, United States
July 2024
$45.0M
Venture - Series Unknown

Founder Contacts

19,000+ verified contacts

Showing 26-50 of 239 portfolio companies

Frequently Asked Questions About OrbiMed

How many companies has OrbiMed invested in?

OrbiMed has invested in 239 companies tracked in our database. The portfolio spans multiple industries and funding stages, from seed-stage startups to late-stage companies.

What industries does OrbiMed invest in?

OrbiMed's top investment sectors include Biotechnology, Health Care, Medical, Therapeutics, Biopharma. The firm invests across 13 different industry categories.

What is OrbiMed's largest investment?

Among tracked funding rounds, Treeline Biosciences received $200.0M in a Series A round. OrbiMed's total known invested capital is $12.2B.

What is the average investment size for OrbiMed?

OrbiMed's average investment size is $87.5M across its portfolio of 239 companies.

What are OrbiMed's most recent investments?

Recent OrbiMed portfolio additions include ImageneBio, Sionna Therapeutics, Apollomics, Lomond Therapeutics, Pinnacle Medicines. These companies were founded in 2020 or later.

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