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OrbiMed Portfolio Companies

Investor actively backing innovative startups and growth-stage companies across various industries and funding rounds.

Last updated: July 2026

OrbiMed Investment Overview

Portfolio Companies
239
Total Invested
$12.2B
Average Investment
$87.5M

OrbiMed's Most Recent Investments (2020+)

Company NameFoundedFunding StageAmountCity
NextCure2025Post Ipo Equity$21.5MBeltsville
Braveheart Bio2025Series A$185.0MSan Francisco
X4 Pharmaceuticals2025Post Ipo Equity$155.3MCambridge
Valneva2025Post Ipo Debt$215.0MSaint-herblain
ReCode Therapeutics2025Debt Financing$29.4MDallas
DarioHealth2025Post Ipo Equity$17.5MNew York
Epigenic Therapeutics2025Series B$60.0MShanghai
Avenzo Therapeutics2025Series B$60.0MSan Diego
Congruence Therapeutics2025Series Unknown$32.0MMontréal
Apollomics2025Post Ipo Equity$4.1MFoster City

Complete List of OrbiMed Portfolio Companies (239)

Export
#CompanyStageAmountLocation
101NextCurePost Ipo Equity$21.5MBeltsville, United States
102Braveheart BioSeries A$185.0MSan Francisco, United States
103X4 PharmaceuticalsPost Ipo Equity$155.3MCambridge, United States
104ValnevaPost Ipo Debt$215.0MSaint-herblain, France
105ReCode TherapeuticsDebt Financing$29.4MDallas, United States
106DarioHealthPost Ipo Equity$17.5MNew York, United States
107Epigenic TherapeuticsSeries B$60.0MShanghai, China
108Avenzo TherapeuticsSeries B$60.0MSan Diego, United States
109Congruence TherapeuticsSeries Unknown$32.0MMontréal, Canada
110ApollomicsPost Ipo Equity$4.1MFoster City, United States
BiopharmaBiotechnologyHealth CareOncology

NextCure is a biopharmaceutical company focused on discovering and developing next generation immuno-oncology-based drugs.

Beltsville, United States
November 2025
$21.5M
Post Ipo Equity

Founder Contacts

19,000+ verified contacts

BiotechnologyLife ScienceTherapeutics

Braveheart Bio is a clinical-stage biotechnology company focused on developing precision therapies in the cardiovascular disease space.

San Francisco, United States
November 2025
$185.0M
Series A

Founder Contacts

19,000+ verified contacts

BiotechnologyClinical TrialsHealth CareOncologyPharmaceuticalTherapeutics

X4 Pharmaceuticals is a clinical-stage oncology company developing oral small molecule CXCR4 antagonists for the treatment.

Cambridge, United States
October 2025
$155.3M
Post Ipo Equity

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CareMedicalTherapeutics

Valneva focuses on the development and commercialization of prophylactic vaccines for infectious diseases.

Saint-herblain, France
October 2025
$215.0M
Post Ipo Debt

Founder Contacts

19,000+ verified contacts

BiopharmaBiotechnologyGeneticsPharmaceuticalTherapeutics

ReCode Therapeutics is a genetic medicines company that specializes in mRNA and gene correction therapeutics.

Dallas, United States
September 2025
$29.4M
Debt Financing

Founder Contacts

19,000+ verified contacts

Health CareHealth DiagnosticsMedical DeviceSoftwareTherapeutics

DarioHealth is a digital therapeutics company engaged in the development and commercialization of patented and proprietary technology.

New York, United States
September 2025
$17.5M
Post Ipo Equity

Founder Contacts

19,000+ verified contacts

BiotechnologyGeneticsHealth CareMedicalTherapeutics

Epigenic Therapeutics is a drug development company that develops gene modulation therapies through the regulation of epigenetic mechanisms.

Shanghai, China
September 2025
$60.0M
Series B

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CareMedicalOncologyTherapeutics

Avenzo Therapeutics specializes in the development of oncology therapies for cancer treatment.

San Diego, United States
September 2025
$60.0M
Series B

Founder Contacts

19,000+ verified contacts

BiotechnologyMedical

Congruence Therapeutics operates as a biotechnology company.

Montréal, Canada
September 2025
$32.0M
Series Unknown

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CareOncologyPharmaceutical

Apollomics is a biopharmaceutical company discovering and developing mono- and combination- oncology therapies to harness the immune system.

Foster City, United States
September 2025
$4.1M
Post Ipo Equity

Founder Contacts

19,000+ verified contacts

BiopharmaBiotechnologyMedicalPharmaceutical

Mineralys Therapeutics is a clinical-stage biopharmaceutical company committed to developing therapy for the treatment of hypertension.

Radnor, United States
September 2025
$287.5M
Post Ipo Equity

Founder Contacts

19,000+ verified contacts

Health CareMedical DeviceTherapeutics

Noctrix Health is an early-stage medical device company that focuses on developing a revolutionary therapy for a chronic illness.

San Francisco, United States
August 2025
$33.5M
Series Unknown

Founder Contacts

19,000+ verified contacts

MedicalTherapeutics

Leal Therapeutics develops novel therapeutics for patients.

Worcester, United States
August 2025
$30.0M
Series A

Founder Contacts

19,000+ verified contacts

Health CareMedical Device

ProVerum Medical is a medtech company that develops novel minimally invasive devices to treat benign prostatic hyperplasia.

Dublin, Ireland
August 2025
$80.0M
Series B

Founder Contacts

19,000+ verified contacts

BiopharmaBiotechnologyMedicalPharmaceuticalProduct ResearchTherapeutics

Minghui Pharmaceutical is a biopharmaceutical business that specializes in immunology and oncology medicines for unmet needs.

Shanghai, China
August 2025
$131.0M
Series Unknown

Founder Contacts

19,000+ verified contacts

BiotechnologyPharmaceuticalTherapeutics

Rhythm is a biopharmaceutical company focused on developing and commercializing peptide therapeutics

Boston, United States
July 2025
$175.0M
Post Ipo Equity

Founder Contacts

19,000+ verified contacts

BiotechnologyLife ScienceTherapeutics

Renasant Bio is a biopharmaceutical company pioneering disease-modifying oral small molecule treatments.

Berkeley, United States
July 2025
$54.5M
Seed

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CareLife SciencePharmaceutical

Forte Biosciences is a biotechnology company that focuses on dermatology.

Sherman Oaks, United States
June 2025
$75.0M
Post Ipo Equity

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CareHealth DiagnosticsMedical

Alpheus Medical provides a novel sonodynamic therapy platform targeting solid body cancers.

Oakdale, United States
May 2025
$52.0M
Series B

Founder Contacts

19,000+ verified contacts

BiotechnologyPharmaceuticalTherapeutics

Sirius Therapeutics is an innovative biotechnology company that focuses on RNAi therapies for cardiovascular diseases.

San Diego, United States
May 2025
$50.0M
Series B

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CareHealth DiagnosticsMedicalOncology

Fore Biotherapeutics is a precision oncology company specializing in cancer therapies guided by functional genomics.

Philadelphia, United States
May 2025
$40.2M
Series D

Founder Contacts

19,000+ verified contacts

Cloud Data ServicesInformation TechnologyMedical

Rimag is a Shenzhen-based medical imaging service provider.

Beijing, China
April 2025
$25.1M
Post Ipo Equity

Founder Contacts

19,000+ verified contacts

BiotechnologyMedical

RayThera is dedicated to developing small molecule therapies specifically targeting unmet needs in immunology.

San Diego, United States
April 2025
$110.0M
Series A

Founder Contacts

19,000+ verified contacts

BiopharmaBiotechnologyHealth CareMedical

Lomond Therapeutics creates pharmacological platforms that target escape mutations.

San Diego, United States
March 2025
$20.0M
Series Unknown

Founder Contacts

19,000+ verified contacts

BiopharmaBiotechnologyHealth CareMedical

Curevo is a clinical-stage biotechnology company developing next-generation, non-mRNA vaccines for infectious diseases.

Bothell, United States
March 2025
$110.0M
Series B

Founder Contacts

19,000+ verified contacts

Showing 101-125 of 239 portfolio companies

Frequently Asked Questions About OrbiMed

How many companies has OrbiMed invested in?

OrbiMed has invested in 239 companies tracked in our database. The portfolio spans multiple industries and funding stages, from seed-stage startups to late-stage companies.

What industries does OrbiMed invest in?

OrbiMed's top investment sectors include Biotechnology, Health Care, Therapeutics, Medical, Pharmaceutical. The firm invests across 16 different industry categories.

What is OrbiMed's largest investment?

Among tracked funding rounds, Mineralys Therapeutics received $287.5M in a Post Ipo Equity round. OrbiMed's total known invested capital is $12.2B.

What is the average investment size for OrbiMed?

OrbiMed's average investment size is $87.5M across its portfolio of 239 companies.

What are OrbiMed's most recent investments?

Recent OrbiMed portfolio additions include NextCure, Braveheart Bio, X4 Pharmaceuticals, Valneva, ReCode Therapeutics. These companies were founded in 2020 or later.

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