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OrbiMed Portfolio Companies

Investor actively backing innovative startups and growth-stage companies across various industries and funding rounds.

Last updated: July 2026

OrbiMed Investment Overview

Portfolio Companies
239
Total Invested
$12.2B
Average Investment
$87.5M

OrbiMed's Most Recent Investments (2020+)

Company NameFoundedFunding StageAmountCity
Cullinan Therapeutics2024Post Ipo Equity$280.0MCambridge
Alterome Therapeutics2024Series B$132.0MSan Diego
Capstan Therapeutics2024Series B$175.0MSan Diego
ImmPACT Bio2024Grant$8.0MCamarillo
Pinnacle Medicines2024Series A$600KDoylestown
Tyra Biosciences2024Post Ipo Equity$200.0MCarlsbad
Keros Therapeutics2024Post Ipo Equity$140.0MLexington
SpringWorks Therapeutics2023Post Ipo Equity$275.0MStamford
Koya Medical2023Series C$30.0MOakland
Alpine Immune Sciences2023Post Ipo Equity$150.0MSeattle

Complete List of OrbiMed Portfolio Companies (239)

Export
#CompanyStageAmountLocation
151Cullinan TherapeuticsPost Ipo Equity$280.0MCambridge, United States
152Alterome TherapeuticsSeries B$132.0MSan Diego, United States
153Capstan TherapeuticsSeries B$175.0MSan Diego, United States
154ImmPACT BioGrant$8.0MCamarillo, United States
155Pinnacle MedicinesSeries A$600KDoylestown, United States
156Tyra BiosciencesPost Ipo Equity$200.0MCarlsbad, United States
157Keros TherapeuticsPost Ipo Equity$140.0MLexington, United States
158SpringWorks TherapeuticsPost Ipo Equity$275.0MStamford, United States
159Koya MedicalSeries C$30.0MOakland, United States
160Alpine Immune SciencesPost Ipo Equity$150.0MSeattle, United States
BiopharmaBiotechnologyMedical DeviceOncology

Cullinan Therapeutics is a developer of an externally sourced cancer therapeutics used to end a drug program quickly.

Cambridge, United States
April 2024
$280.0M
Post Ipo Equity

Founder Contacts

19,000+ verified contacts

BiopharmaBiotechnologyPharmaceutical

Alterome Therapeutics is a biopharmaceutical company developing alteration-specific targeted therapies.

San Diego, United States
April 2024
$132.0M
Series B

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CareMedicalTherapeutics

Capstan Therapeutics develops in vivo mRNA and gene-editing medicines for a broad range of diseases.

San Diego, United States
March 2024
$175.0M
Series B

Founder Contacts

19,000+ verified contacts

BiotechnologyLife Science

ImmPACT Bio USA is developing novel cell therapies for treating cancer.

Camarillo, United States
February 2024
$8.0M
Grant

Founder Contacts

19,000+ verified contacts

BiopharmaBiotechnologyMedical

Pinnacle Medicines is a peptide drug discovery company that provides peptide modality for medical needs.

Doylestown, United States
February 2024
$600K
Series A

Founder Contacts

19,000+ verified contacts

BiotechnologyLife ScienceOncologyTherapeutics

Tyra Biosciences is a biotechnology company targeting new pathways of acquired resistance in oncology with purpose-built drugs.

Carlsbad, United States
February 2024
$200.0M
Post Ipo Equity

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CarePharmaceuticalTherapeutics

Keros is a clinical-stage biopharmaceutical company focusing on the discovery, development, and commercialization of novel treatments.

Lexington, United States
January 2024
$140.0M
Post Ipo Equity

Founder Contacts

19,000+ verified contacts

BiopharmaBiotechnologyTherapeutics

SpringWorks Therapeutics is a biopharmaceutical company that develops medicines for patients with severe rare diseases and cancer.

Stamford, United States
December 2023
$275.0M
Post Ipo Equity

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CareInternetPharmaceutical

Koya Medical is a transformative healthcare company developing breakthrough treatments for lymphedema and venous diseases.

Oakland, United States
November 2023
$30.0M
Series C

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CareMedical

Alpine Immune Sciences is an immunotherapy company focused on developing treatments for autoimmune and inflammatory diseases.

Seattle, United States
November 2023
$150.0M
Post Ipo Equity

Founder Contacts

19,000+ verified contacts

Biotechnology

Terremoto Biosciences is a biotechnology company leveraging the power of lysine-based covalency to develop optimized medicines.

San Francisco, United States
November 2023
$175.0M
Series B

Founder Contacts

19,000+ verified contacts

Health Care

Forward Therapeutics is a biopharma comapny targeting treatment of chronic inflammatory disorders.

Palm Beach Gardens, United States
October 2023
$50.0M
Series A

Founder Contacts

19,000+ verified contacts

BiopharmaBiotechnologyMedicalTherapeutics

Rampart Bioscience develops gene medicines to provide long-lasting treatments for a wide range of diseases.

La Jolla, United States
October 2023
$85.0M
Series A

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CareTherapeutics

Harpoon Therapeutics is a clinical-stage immunotherapy company focused on the development of novel T-cell recruiting biologic therapies.

South San Francisco, United States
October 2023
$100.0M
Post Ipo Equity

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CareHealth DiagnosticsMedical

Adela creates develops technologies centered around detecting high-risk conditions like cancer through routine blood tests.

Foster City, United States
September 2023
$48.0M
Series A

Founder Contacts

19,000+ verified contacts

BiotechnologyPharmaceuticalTherapeutics

Corteria Pharmaceuticals develops first-in-class drugs in heart failure subpopulations.

Paris, France
September 2023
$69.5M
Series A

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CareTherapeutics

Aeglea BioTherapeutics is a clinical-stage biotechnology company that develops enzyme therapies for rare metabolic diseases.

Austin, United States
June 2023
$210.0M
Post Ipo Equity

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CarePharmaceuticalTherapeutics

Upstream Bio focuses on developing an antibody therapy for the treatment of severe asthma.

Waltham, United States
June 2023
$200.0M
Series B

Founder Contacts

19,000+ verified contacts

BiotechnologyMedicalPharmaceutical

Stemirna Therapeutics is a RNA technology based drug development company designed to maximize the potential of RNA science.

Beijing, China
May 2023
Series D

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CareHealth DiagnosticsOncologyTherapeutics

Ikena Oncology develops differentiated therapies to target cancer growth and resistance, focusing on Hippo and RAS signaling pathways.

Boston, United States
May 2023
$40.0M
Post Ipo Equity

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CareMedicalPharmaceuticalWellness

Amolyt Pharma specializes in peptides for the treatment of rare endocrine and metabolic disorders.

Écully, France
January 2023
$138.6M
Series C

Founder Contacts

19,000+ verified contacts

BeautyHealth CareHospitalMedical

Ruipeng Pet Hospital is a Shenzhen-based pet medical and beauty care hospital operator.

Shenzhen, China
December 2022
Private Equity

Founder Contacts

19,000+ verified contacts

BiotechnologyGenetics

iECURE is a mutation-agnostic in vivo gene editing company striving to cure devastating diseases with high unmet needs.

Philadelphia, United States
November 2022
$65.0M
Series A

Founder Contacts

19,000+ verified contacts

Clinical Trials

Immvira’s scientific objectives are based on numerous experimental designs of oHSV and outcomes of clinical trials.

Shenzhen, China
October 2022
Series C

Founder Contacts

19,000+ verified contacts

BiopharmaBiotechnologyHealth Care

ACELYRIN is a biopharma company that identifies, acquires, and accelerates the development and commercialization of life-changing therapies.

Los Angeles, United States
September 2022
$300.0M
Series C

Founder Contacts

19,000+ verified contacts

Showing 151-175 of 239 portfolio companies

Frequently Asked Questions About OrbiMed

How many companies has OrbiMed invested in?

OrbiMed has invested in 239 companies tracked in our database. The portfolio spans multiple industries and funding stages, from seed-stage startups to late-stage companies.

What industries does OrbiMed invest in?

OrbiMed's top investment sectors include Biotechnology, Health Care, Therapeutics, Medical, Pharmaceutical. The firm invests across 16 different industry categories.

What is OrbiMed's largest investment?

Among tracked funding rounds, ACELYRIN received $300.0M in a Series C round. OrbiMed's total known invested capital is $12.2B.

What is the average investment size for OrbiMed?

OrbiMed's average investment size is $87.5M across its portfolio of 239 companies.

What are OrbiMed's most recent investments?

Recent OrbiMed portfolio additions include Cullinan Therapeutics, Alterome Therapeutics, Capstan Therapeutics, ImmPACT Bio, Pinnacle Medicines. These companies were founded in 2020 or later.

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