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RA Capital Management Portfolio Companies

Investor actively backing innovative startups and growth-stage companies across various industries and funding rounds.

Last updated: July 2026

RA Capital Management Investment Overview

Portfolio Companies
369
Total Invested
$19.0B
Average Investment
$91.5M

RA Capital Management's Most Recent Investments (2020+)

Company NameFoundedFunding StageAmountCity
ARS Pharmaceuticals2025Post-IPO DebtUndisclosedSan Diego
Pepgen2025Post-IPO EquityUndisclosedOxford
KalVista Pharmaceuticals2025Post-IPO DebtUndisclosedCambridge
Spero Therapeutics2022Post-IPO EquityUndisclosedCambridge
Ceribell2022Series CUndisclosedMountain View
Dignify Therapeutics2024GrantUndisclosedRaleigh
HilleVax2023Post-IPO EquityUndisclosedBoston
Forge Biologics2022Series CUndisclosedGrove City
Plexium2025Series CUndisclosedSan Diego
Empatica2022Series BUndisclosedCambridge

Complete List of RA Capital Management Portfolio Companies (369)

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#CompanyStageAmountLocation
1ARS PharmaceuticalsPost-IPO DebtUndisclosedSan Diego, United States
2PepgenPost-IPO EquityUndisclosedOxford, United Kingdom
3KalVista PharmaceuticalsPost-IPO DebtUndisclosedCambridge, United States
4Spero TherapeuticsPost-IPO EquityUndisclosedCambridge, United States
5CeribellSeries CUndisclosedMountain View, United States
6Dignify TherapeuticsGrantUndisclosedRaleigh, United States
7HilleVaxPost-IPO EquityUndisclosedBoston, United States
8Forge BiologicsSeries CUndisclosedGrove City, United States
9PlexiumSeries CUndisclosedSan Diego, United States
10EmpaticaSeries BUndisclosedCambridge, United States
BiopharmaHealth CareMedicalPharmaceutical

ARS Pharmaceuticals is a stealth pharmaceutical company that specializes in developing anti allergy drugs.

San Diego, United States
September 2025
Post-IPO Debt

Founder Contacts

19,000+ verified contacts

BiotechnologyClinical TrialsMedical

PepGen is empowering nucleic acid therapeutics to go the distance.

Oxford, United Kingdom
September 2025
Post-IPO Equity

Founder Contacts

19,000+ verified contacts

BiopharmaBiotechnologyDiabetesHealth CarePharmaceutical

KalVista Pharmaceuticals focuses on developing oral medicines, particularly for managing hereditary angioedema.

Cambridge, United States
September 2025
Post-IPO Debt

Founder Contacts

19,000+ verified contacts

BiotechnologyMedical DeviceTherapeutics

Spero Therapeutics develops therapeutics for treatment of gram-negative infections.

Cambridge, United States
September 2022
Post-IPO Equity

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CareHealth DiagnosticsMedical Device

Ceribell focuses on making electroencephalography accessible, efficient, and cost-effective.

Mountain View, United States
September 2022
Series C

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CarePharmaceuticalTherapeutics

Dignify Therapeutics is a drug development company focused on delivering novel drug therapies for bladder and bowel disorders in spinal.

Raleigh, United States
September 2024
Grant

Founder Contacts

19,000+ verified contacts

BiopharmaBiotechnologyHealth CarePharmaceutical

HilleVax is a biopharmaceutical company that focuses on the development and commercialization of novel vaccines.

Boston, United States
September 2023
Post-IPO Equity

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CareMedicalTherapeutics

Forge Biologics is a gene therapy development engine, enabling access to life changing gene therapy programs.

Grove City, United States
September 2022
Series C

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CareMedicalPharmaceuticalTherapeutics

Plexium develops a targeted protein degradation platform to find new therapies for cancer and other diseases.

San Diego, United States
August 2025
Series C

Founder Contacts

19,000+ verified contacts

Artificial Intelligence (AI)Health CareMedicalMedical DeviceWearables

Empatica is an affective computing company focused on human data analytics.

Cambridge, United States
August 2022
Series B

Founder Contacts

19,000+ verified contacts

Biotechnology

T-knife is a developer of T cell receptors intended for T cell therapy of cancer.

Berlin, Germany
August 2021
Series B

Founder Contacts

19,000+ verified contacts

MedicalPharmaceuticalTherapeutics

Iterum Therapeutics is a clinical-stage pharmaceutical company that develops significantly differentiated anti-infectives.

Dublin, Ireland
August 2025
Post-IPO Equity

Founder Contacts

19,000+ verified contacts

BiotechnologyLife Science

GentiBio is a biotherapeutics company developing engineered regulatory T cells programmed to treat autoimmune allergic diseases.

Seattle, United States
August 2021
Series A

Founder Contacts

19,000+ verified contacts

BiopharmaBiotechnologyHealth CarePharmaceutical

Day One Biopharmaceuticals develops targeted therapies to treat people with life-threatening diseases.

South San Francisco, United States
July 2024
Post-IPO Equity

Founder Contacts

19,000+ verified contacts

Health CareMedicalPharmaceuticalTherapeutics

LENZ Therapeutics operates as an organization engaged in the late-stage clinical development of pharmaceuticals for the eyes.

Del Mar, United States
July 2024
Post-IPO Equity

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CareLife Science

Ocelot Bio brings new treatment options to patients with severe liver disease.

San Diego, United States
July 2023
Debt Financing

Founder Contacts

19,000+ verified contacts

ElectronicsManufacturingRenewable Energy

AM Batteries manufactures Li-ion batteries using solvent-free electrode manufacturing technology.

Chelmsford, United States
July 2024
Grant

Founder Contacts

19,000+ verified contacts

BiotechnologyInformation TechnologyMedicalSoftware

Septerna is a biotech firm unlocking diverse drug discovery potential in G protein-coupled receptors across various diseases.

San Francisco, United States
July 2023
Series B

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CareMedicalTherapeutics

Tango Therapeutics is a biotechnology company that is developing next generation cancer therapies.

Cambridge, United States
June 2026
Post-IPO Equity

Founder Contacts

19,000+ verified contacts

BiopharmaBiotechnologyMedicalPharmaceutical

Mineralys Therapeutics is a clinical-stage biopharmaceutical company committed to developing therapy for the treatment of hypertension.

Radnor, United States
June 2026
Post-IPO Debt

Founder Contacts

19,000+ verified contacts

BiopharmaHealth CareTherapeutics

Jade Biosciences is developing transformative therapies to redefine the standard of care for inflammation and immunology indications.

Waltham, United States
June 2026
Post-IPO Equity

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CareHealth DiagnosticsTherapeutics

Celcuity is a biotechnology company translating discoveries of new cancer sub-types into expanded therapeutic options for cancer patients.

Hamel, United States
June 2026
Post-IPO Debt

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CareOncologyPharmaceutical

Pyxis Oncology is a biotechnology firm that develops antibody therapeutics intended to promote the body's immune response to cancer.

Boston, United States
June 2026
Post-IPO Equity

Founder Contacts

19,000+ verified contacts

BioinformaticsBiotechnologyHealth CareMedical

Blueprint Medicines develops precision therapies for genomically defined cancers and rare diseases.

Cambridge, United States
June 2022
Post-IPO Equity

Founder Contacts

19,000+ verified contacts

BiopharmaBiotechnologyHealth CareLife ScienceOncologyTherapeutics

ALX Oncology is a preclinical stage biotechnology company developing innovative immuno-oncology therapies for cancer.

San Francisco, United States
June 2026
Post-IPO Debt

Founder Contacts

19,000+ verified contacts

Showing 1-25 of 369 portfolio companies

Frequently Asked Questions About RA Capital Management

How many companies has RA Capital Management invested in?

RA Capital Management has invested in 369 companies tracked in our database. The portfolio spans multiple industries and funding stages, from seed-stage startups to late-stage companies.

What industries does RA Capital Management invest in?

RA Capital Management's top investment sectors include Biotechnology, Health Care, Medical, Pharmaceutical, Therapeutics. The firm invests across 20 different industry categories.

What is the average investment size for RA Capital Management?

RA Capital Management's average investment size is $91.5M across its portfolio of 369 companies.

What are RA Capital Management's most recent investments?

Recent RA Capital Management portfolio additions include ARS Pharmaceuticals, Pepgen, KalVista Pharmaceuticals, Spero Therapeutics, Ceribell. These companies were founded in 2020 or later.

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