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RA Capital Management Portfolio Companies

Investor actively backing innovative startups and growth-stage companies across various industries and funding rounds.

Last updated: July 2026

RA Capital Management Investment Overview

Portfolio Companies
369
Total Invested
$19.0B
Average Investment
$91.5M

RA Capital Management's Most Recent Investments (2020+)

Company NameFoundedFunding StageAmountCity
Adela2026Convertible Note$48.0MFoster City
Edgewise Therapeutics2025Post-IPO EquityUndisclosedBoulder
Prelude Therapeutics2026Post-IPO EquityUndisclosedWilmington
Terremoto Biosciences2026Series CUndisclosedSan Francisco
ADCendo2026Series C$135.0MCopenhagen
CDR-Life AG2022Series AUndisclosedSchlieren
AN2 Therapeutics2026Post-IPO EquityUndisclosedMenlo Park
Claris Biotherapeutics2025Debt FinancingUndisclosedJersey City
Solid Biosciences2026Post Ipo Equity$240.0MCharlestown
Sionna Therapeutics2024Series CUndisclosedNatick

Complete List of RA Capital Management Portfolio Companies (369)

Export
#CompanyStageAmountLocation
51AdelaConvertible Note$48.0MFoster City, United States
52Edgewise TherapeuticsPost-IPO EquityUndisclosedBoulder, United States
53Prelude TherapeuticsPost-IPO EquityUndisclosedWilmington, United States
54Terremoto BiosciencesSeries CUndisclosedSan Francisco, United States
55ADCendoSeries C$135.0MCopenhagen, Denmark
56CDR-Life AGSeries AUndisclosedSchlieren, Switzerland
57AN2 TherapeuticsPost-IPO EquityUndisclosedMenlo Park, United States
58Claris BiotherapeuticsDebt FinancingUndisclosedJersey City, United States
59Solid BiosciencesPost Ipo Equity$240.0MCharlestown, United States
60Sionna TherapeuticsSeries CUndisclosedNatick, United States
BiotechnologyHealth CareHealth DiagnosticsMedical

Adela creates develops technologies centered around detecting high-risk conditions like cancer through routine blood tests.

Foster City, United States
April 2026
$48.0M
Convertible Note

Founder Contacts

19,000+ verified contacts

BiopharmaBiotechnologyHealth Care

Edgewise Therapeutics is a clinical-stage biopharmaceutical company focused on the discovery, development and commercialization.

Boulder, United States
April 2025
Post-IPO Equity

Founder Contacts

19,000+ verified contacts

BiopharmaBiotechnologyPharmaceuticalTherapeutics

Prelude Therapeutics designs and develops small molecule therapies targeting key drivers of cancer cell growth and resistance.

Wilmington, United States
April 2026
Post-IPO Equity

Founder Contacts

19,000+ verified contacts

Biotechnology

Terremoto Biosciences is a biotechnology company leveraging the power of lysine-based covalency to develop optimized medicines.

San Francisco, United States
April 2026
Series C

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CareMedicalTherapeutics

Adcendo is a biotech company that develops antibody-drug conjugates (ADCs) to target cancers with high unmet medical needs.

Copenhagen, Denmark
April 2026
$135.0M
Series C

Founder Contacts

19,000+ verified contacts

BiotechnologyOncology

CDR-Life AG is a biotech company that develops innovative therapeutic antibody fragments with a focus on immuno-oncology.

Schlieren, Switzerland
April 2022
Series A

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CarePharmaceutical

AN2 Therapeutics focuses on modern biomedical and drug development expertise to provide transformational medicines.

Menlo Park, United States
March 2026
Post-IPO Equity

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CareTherapeutics

Claris Biotherapeutics develops a topical formulation intended to cure corneal wounds, ulcers, and scars.

Jersey City, United States
March 2025
Debt Financing

Founder Contacts

19,000+ verified contacts

BiotechnologyGeneticsHealth CareMedical

Solid Biosciences is a life science company that conducts research for the treatment of Duchenne muscular dystrophy.

Charlestown, United States
March 2026
$240.0M
Post Ipo Equity

Founder Contacts

19,000+ verified contacts

BiotechnologyGeneticsHealth CareMedicalPharmaceuticalTherapeutics

Sionna Therapeutics is developing novel small molecule therapies to treat cystic fibrosis (CF).

Natick, United States
March 2024
Series C

Founder Contacts

19,000+ verified contacts

BiotechnologyGeneticsHealth CareHealth Diagnostics

Orchard Therapeutics is a biotechnology company dedicated to assisting patients through innovative gene therapies.

London, United Kingdom
March 2023
Post-IPO Equity

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CareLife ScienceTherapeutics

Atavistik Bio is a biotechnology company that develops precision allosteric small molecules aimed at treating metabolic diseases and cancer.

Cambridge, United States
March 2026
$40.0M
Series B

Founder Contacts

19,000+ verified contacts

BiotechnologyLife SciencePrecision MedicineTherapeutics

OnKure is a clinical-stage biopharma company developing precision medicines targeting validated cancer drivers.

Boulder, United States
March 2026
Post-IPO Equity

Founder Contacts

19,000+ verified contacts

BiopharmaBiotechnologyHealth CareTherapeutics

Palisade Bio is a clinical-stage biopharmaceutical company that develops therapies for acute and chronic gastrointestinal complications.

Carlsbad, United States
March 2026
Post-IPO Equity

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CarePharmaceuticalTherapeutics

Stoke is developing antisense oligonucleotide medicines that target RNA splicing to increase gene expression for treatment.

Bedford, United States
March 2024
Post-IPO Equity

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CareMedical

Terrestrial Bio engages in developing biomedical innovations with a focus on improving access to vaccines.

Cambridge, United States
March 2026
$50.0M
Series C

Founder Contacts

19,000+ verified contacts

BiopharmaBiotechnologyMedicalTherapeutics

Pinnacle Medicines is a peptide drug discovery company that provides peptide modality for medical needs.

Doylestown, United States
March 2026
Series B

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth Care

Nkarta Therapeutics is a developer of cell engineering platform created to build the next generation of cell therapies.

South San Francisco, United States
March 2024
Post-IPO Equity

Founder Contacts

19,000+ verified contacts

BiotechnologyProduct ResearchTherapeutics

Candid Therapeutics develops therapies for autoimmune diseases using antibody-based technologies that modulate immune system activity.

San Diego, United States
March 2026
Undisclosed

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CareMedicalTherapeutics

Capstan Therapeutics develops in vivo mRNA and gene-editing medicines for a broad range of diseases.

San Diego, United States
March 2024
Series B

Founder Contacts

19,000+ verified contacts

BiopharmaBiotechnologyLife SciencePharmaceuticalTherapeutics

Inhibrx is a clinical-stage biotechnology company that focuses on developing a broad pipeline of biologic therapeutic candidates.

La Jolla, United States
March 2026
Post-IPO Debt

Founder Contacts

19,000+ verified contacts

BiotechnologyClinical TrialsTherapeutics

SAB Biotherapeutics is a clinical-stage biopharmaceutical development company.

Sioux Falls, United States
March 2026
$85.0M
Post Ipo Equity

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CareHealth DiagnosticsMedical

Unicycive Therapeutics provides development programs that focus on treating kidney diseases with unmet medical needs.

Los Altos, United States
March 2024
Post-IPO Equity

Founder Contacts

19,000+ verified contacts

BiopharmaBiotechnologyLife Science

Equillium is a biotechnology company that develops products for autoimmune and inflammatory disorders with an unmet medical need.

La Jolla, United States
March 2026
$35.0M
Post Ipo Equity

Founder Contacts

19,000+ verified contacts

AgricultureAgTechBiotechnology

NAPIGEN is a biotechnology company that addresses novel genome engineering of various organisms such as plants, microbes, and animals.

Wilmington, United States
March 2024
Grant

Founder Contacts

19,000+ verified contacts

Showing 51-75 of 369 portfolio companies

Frequently Asked Questions About RA Capital Management

How many companies has RA Capital Management invested in?

RA Capital Management has invested in 369 companies tracked in our database. The portfolio spans multiple industries and funding stages, from seed-stage startups to late-stage companies.

What industries does RA Capital Management invest in?

RA Capital Management's top investment sectors include Biotechnology, Health Care, Therapeutics, Medical, Biopharma. The firm invests across 15 different industry categories.

What is RA Capital Management's largest investment?

Among tracked funding rounds, Solid Biosciences received $240.0M in a Post Ipo Equity round. RA Capital Management's total known invested capital is $19.0B.

What is the average investment size for RA Capital Management?

RA Capital Management's average investment size is $91.5M across its portfolio of 369 companies.

What are RA Capital Management's most recent investments?

Recent RA Capital Management portfolio additions include Adela, Edgewise Therapeutics, Prelude Therapeutics, Terremoto Biosciences, ADCendo. These companies were founded in 2020 or later.

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