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The Column Group — Portfolio

Investor actively backing innovative startups and growth-stage companies across various industries and funding rounds.

42
Companies
$3.9B
Total invested
$95.2M
Avg. check
12
Industries
Biotechnology 22Health Care 18Therapeutics 15Medical 9Life Science 7Neuroscience 2+6 more
Founder contacts

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Portfolio companies

Showing 124 of 42
Circle Pharma
September 2024

Circle Pharma is a biotechnology company creating bioavailable macrocyclic peptide therapeutics that target protein-protein interactions.

Biotechnology · San Francisco$90.0M Series D
Nura Bio
June 2026

Nura Bio is a biotechnology company that develops neuroprotective therapies for neurological disorders.

Biotechnology · South San Francisco$73.8M Series B
A2 Biotherapeutics
May 2025

A2 Biotherapeutics develops T cell therapies targeting solid tumors precisely.

Biotechnology · Agoura Hills$300K Grant
ORIC Pharmaceuticals
May 2025

ORIC Pharmaceuticals is a biopharmaceutical company that develops treatments that target the causes of therapeutic resistance.

Biopharma · South San Francisco$125.0M Post-IPO Equity
Tortugas Neuroscience
April 2026

Tortugas Neuroscience is a neurology-focused biotech company developing novel medicines.

Biotechnology · Framingham$106.0M Series A
Revolution Medicines
April 2026

Revolution Medicines is an innovative and dynamic organization of expert biologists, chemists, pharmacologists, clinical scientists.

Health Care · Redwood City$1.5B Post-IPO Equity
Gritstone bio
April 2024

Gritstone bio is a biotechnology company that develops immunotherapies for cancer and infectious diseases.

Biotechnology · Emeryville$32.5M Post-IPO Equity
Atavistik Bio
March 2026

Atavistik Bio is a biotechnology company that develops precision allosteric small molecules aimed at treating metabolic diseases and cancer.

Biotechnology · Cambridge$40.0M Series B
Surrozen
March 2025

Surrozen is a biopharmaceutical that focuses on unlocking the body’s regenerative power to treat injury and disease.

Biotechnology · South San Francisco$175.0M Post-IPO Equity
Casma Therapeutics
March 2026

Casma Therapeutics is a biotechnology company harnessing the natural cellular process of autophagy to design new medicines.

Biotechnology · Cambridge$7.6M Grant
Tr1x
October 2025

Tr1x is a biotechnology company developing novel cellular immunotherapies for patients with autoimmune and inflammatory diseases.

Biotechnology · San Diego$50.0M Venture - Series Unknown
Kenai Therapeutics
February 2024

Kenai Therapeutics focuses on developing therapies for neurodegenerative movement disorders.

Biotechnology · San Diego$82.0M Series A
Kimia Therapeutics
December 2023

Kimia is a drug discovery company applying high throughput precision chemistry in combination.

Biotechnology · Berkeley$55.0M Series A
InduPro
January 2026

InduPro deevlops proximity-based protein therapeutics that modulate cell-surface protein interactions to treat disease.

Biotechnology · SeattleCorporate Round
Remix Therapeutics
January 2024

Remix Therapeutics is a biotechnology company that is working on developing small molecule medicines.

Biotechnology · Cambridge$60.0M Venture - Series Unknown
Effector Therapeutics
January 2024

Effector Therapeutics is an early-stage company focused on the discovery and development of small molecule cancer therapeutics.

Biotechnology · San Diego$15.0M Post-IPO Equity
Ribon Therapeutics
December 2022

Ribon Therapeutics is a biotechnology company focused on the development of therapeutics treatments targeting stress support pathways.

Biotechnology · Cambridge$25.0M Venture - Series Unknown
Tenaya Therapeutics
December 2025

Tenaya Therapeutics a clinical-stage biotechnology company that develops novel therapies to treat heart diseases.

Biopharma · San Francisco$60.0M Post-IPO Equity
Escient Pharmaceuticals
November 2022

Escient Pharmaceuticals is a privately-held biotechnology company focusing on the advancement of G Protein-Coupled Receptor targeted drugs.

Biotechnology · San Diego$120.0M Series C
Velia
January 2022

Velia is a biotech company that discovers and develops the therapeutic potential of human proteins.

Biotechnology · San Diego$55.0M Series A
NILO Therapeutics
October 2025

NILO Therapeutics is a biotechnology and therapeutics company.

Biotechnology · New York$101.0M Series A
Judo Bio
October 2024

Judo Bio is a biotechnology company that develops precision therapeutics targeting specific cell populations to address genetic diseases.

Biotechnology · Cambridge$75.0M Series A
Hexagon Bio
October 2022

Hexagon Bio is a data-driven biotech company developing targeted small molecule therapeutics.

Biotechnology · Menlo Park$77.3M Series B

Where The Column Group invests

Biotechnology22
Health Care18
Therapeutics15
Medical9
Life Science7
Neuroscience2

About The Column Group's portfolio

How many companies has The Column Group invested in?

The Column Group has invested in 42 companies tracked in our database. The portfolio spans multiple industries and funding stages, from seed-stage startups to late-stage companies.

What industries does The Column Group invest in?

The Column Group's top investment sectors include Biotechnology, Health Care, Therapeutics, Medical, Life Science. The firm invests across 12 different industry categories.

What is The Column Group's largest investment?

Among tracked funding rounds, Revolution Medicines received $1.5B in a Post-IPO Equity round. The Column Group's total known invested capital is $3.9B.

What is the average investment size for The Column Group?

The Column Group's average investment size is $95.2M across its portfolio of 42 companies.

What are The Column Group's most recent investments?

Recent The Column Group portfolio additions include Circle Pharma, Nura Bio, A2 Biotherapeutics, ORIC Pharmaceuticals, Tortugas Neuroscience. These companies were founded in 2020 or later.

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