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.406 Ventures — Portfolio

Investor actively backing innovative startups and growth-stage companies across various industries and funding rounds.

77
Companies
$1.6B
Total invested
$24.0M
Avg. check
42
Industries
Health Care 12Artificial Intelligence (AI) 9SaaS 7Machine Learning 5Big Data 4Data Integration 4+36 more
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Portfolio companies

Showing 124 of 77
Simon AI
August 2023

Simon AI provides an AI-driven CDP that activates live customer and contextual data for 1:1 marketing and journey orchestration.

Advertising · New York$54.0M Series D
ClosedLoop
August 2022

ClosedLoop is healthcare's data science platform, helping healthcare organizations use AI / ML to improve outcomes and reduce costs.

Artificial Intelligence (AI) · Austin$25K Venture - Series Unknown
ThreatX
August 2022

ThreatX is a web application and API protection platform that enables enterprises to secure all their applications.

Analytics · Boston$30.0M Series B
Gamalon
July 2021

Gamalon is a developer of an AI-based machine intelligence technology designed to write and rewrite own Bayesian programs.

Artificial Intelligence (AI) · Boston$1.5M Debt Financing
Laudio
June 2023

An AI-enhanced platform for frontline leaders that helps health systems improve engagement, operational efficiency, and patient experience.

Artificial Intelligence (AI) · Boston$13.0M Series B
Abacus Insights
June 2022

Abacus Insights offers a data management solution to help healthcare providers improve costs and member outcomes for customers.

Analytics · Boston$40.9M Series C
InStride Health
June 2026

InStride Health provides evidence-based OCD and anxiety treatment to keep kids and teenagers engaged along the way.

Health Care · Boston$30.0M Series C
Telmai
June 2023

Data Reliability Agent for Open Data Lakes

Analytics · San FranciscoSeed
Redox
May 2025

Redox is an EHR integration and healthcare platform that accelerates the development and distribution of healthcare software solutions.

Data Integration · Madison$12.3M Convertible Note
Bobsled, Inc.
April 2023

Bobsled is the fastest way to share data to any cloud or platform.

Big Data · Los Angeles$17.0M Series A
Wellist
February 2023

Wellist gives healthcare clients the insights and tools they need to address actual human needs.

Health Care · Boston$165K Debt Financing
Promethium
February 2022

Promethium is the pioneer of the AI-Powered Data Fabric that aims to deliver seamless self-service to generate data products in real time.

Analytics · Menlo Park$26.0M Series A
GreatHorn
February 2022

GreatHorn provides protection for cloud email systems, via advanced threat detection, automated defense, and integrated incident response.

Cyber Security · Waltham$103K Venture - Series Unknown
RapidFire AI
September 2025

RapidFire AI provides an agile deep learning development platform to accelerate AI development while reducing infrastructure costs

Artificial Intelligence (AI) · Palo Alto$4.0M Pre-Seed
Diana Health
September 2025

Diana Health offers personalized women's healthcare services in maternity, gynecology, menopause, mental health, and wellness.

Health Care · New York$55.0M Series C
Equip Health
July 2025

Equip Health provides a virtual eating disorder treatment program designed to assist families recover from eating disorders at home.

Fitness · San Diego$46.6M Venture - Series Unknown
Bluebird Kids Health
March 2025

Bluebird Kids Health delivers superior treatment to help every kid grow.

Health Care · Boston$31.5M Series A
Rad Security
February 2025

The Future of Security: AI-Driven, Real-Time Defense

Event Management · San Francisco$14.0M Series A
Lynx
February 2025

Lynx provides an API-driven platform for businesses to integrate healthcare financial services, payments, banking, and investments.

FinTech · Boston$27.0M Series A
Mindgard
December 2024

Mindgard empowers enterprise security teams to deploy AI and GenAI securely.

Artificial Intelligence (AI) · London$8.2M Venture - Series Unknown
Nema Health
November 2024

Nema provides comprehensive trauma care administered by PTSD-trained therapists.

Health Care · New York$14.5M Series A
Heartbeat Health
July 2024

Heartbeat Health is a digital health company that utilizes technology to improve cardiovascular disease prevention and management.

Health Care · New York$25.0M Series C
Humata Health
June 2024

Humata Health is an AI-enabled deep clinical integration that creates prior authorizations for payers and providers using AI and automation.

Artificial Intelligence (AI) · Winter Park$25.0M Series A
HYPR
June 2024

HYPR is an identity assurance company that specializes in passwordless authentication solutions.

Cyber Security · New York$30.0M Venture - Series Unknown

Where .406 Ventures invests

Health Care12
Artificial Intelligence (AI)9
SaaS7
Machine Learning5
Big Data4
Data Integration4

About .406 Ventures's portfolio

How many companies has .406 Ventures invested in?

.406 Ventures has invested in 77 companies tracked in our database. The portfolio spans multiple industries and funding stages, from seed-stage startups to late-stage companies.

What industries does .406 Ventures invest in?

.406 Ventures's top investment sectors include Health Care, Artificial Intelligence (AI), SaaS, Machine Learning, Big Data. The firm invests across 42 different industry categories.

What is .406 Ventures's largest investment?

Among tracked funding rounds, Diana Health received $55.0M in a Series C round. .406 Ventures's total known invested capital is $1.6B.

What is the average investment size for .406 Ventures?

.406 Ventures's average investment size is $24.0M across its portfolio of 77 companies.

What are .406 Ventures's most recent investments?

Recent .406 Ventures portfolio additions include Simon AI, ClosedLoop, ThreatX, Gamalon, Laudio. These companies were founded in 2020 or later.

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