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Adage Capital Management — Portfolio, Page 3

Investor actively backing innovative startups and growth-stage companies across various industries and funding rounds.

73
Companies
$10.9B
Total invested
$148.9M
Avg. check
23
Industries
Biotechnology 22Health Care 12Therapeutics 11Medical 7Pharmaceutical 7Biopharma 5+17 more
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Portfolio companies

Showing 49–72 of 73
Pepgen
September 2025

PepGen is empowering nucleic acid therapeutics to go the distance.

Biotechnology · Oxford$115.0M Post Ipo Equity
Arvinas
August 2025

Arvinas advances therapies degrading disease-causing proteins for life-threatening diseases, from discovery to commercialization.

Biotechnology · New HavenPost Ipo Equity
SiMa.ai
August 2025

SiMa.ai is a developer of machine learning technology to deliver a software-centric platform.

AI Infrastructure · San Jose$85.0M Series C
Trevi Therapeutics
June 2025

Trevi Therapeutics is a clinical-stage biopharmaceutical company that develops drugs for treating uremic pruritus.

Biotechnology · Sandy Hook$115.1M Post Ipo Equity
Tectonic Therapeutic
February 2025

Tectonic Therapeutic is a biotechnology company which focuses on scientific research in biochemistry and molecular pharmacology.

Biotechnology · Watertown$185.0M Post Ipo Equity
Cullinan Therapeutics
April 2024

Cullinan Therapeutics is a developer of an externally sourced cancer therapeutics used to end a drug program quickly.

Biopharma · Cambridge$280.0M Post Ipo Equity
Akero Therapeutics
March 2024

Akero Therapeutics is a biotechnology company focused on reversing the NASH epidemic by restoring the body’s metabolism to a balanced state.

Biotechnology · Cambridge$366.9M Post Ipo Equity
Applied Therapeutics
February 2024

Applied Therapeutics uses drug-development approach to target molecules and pathways that has roles in fatal or debilitating diseases.

Biotechnology · New York$100.0M Post Ipo Equity
Beckley Psytech
January 2024

Beckley Psytech is a biotechnology company developing psychedelic-based medicines for mental health conditions.

Biotechnology · Beckley$40.0M Undisclosed
Arcellx
November 2023

Arcellx develops engineered cell-based immunotherapies for the treatment of cancer and other serious diseases.

Biopharma · Redwood City$200.0M Post Ipo Equity
Cerevel Therapeutics
October 2023

Cerevel Therapeutics is a biopharmaceutical company that develops drugs to treat neurological and neuropsychiatric disorders.

Biotechnology · Boston$450.0M Post Ipo Equity
Poseida Therapeutics
August 2023

Poseida Therapeutics is a biopharmaceutical company utilizing gene engineering capabilities to develop targeted therapeutics.

Biopharma · San Diego$50.0M Post Ipo Equity
connectRN
May 2023

ConnectRN is a tech-enabled network built to improve clinicians' lives through access to community, opportunity, and support.

Health Care · Waltham$750K Convertible Note
MedAvail
March 2023

MedAvail focuses on the discovery, development, and commercialization of advanced nutrition products.

Biotechnology · Mississauga$16.0M Post Ipo Equity
Aptinyx
November 2022

Aptinyx Inc. is a biopharmaceutical company.

Biopharma · Evanston$5.6M Grant
Werewolf Therapeutics
May 2022

Werewolf Therapeutics operates as an oncology biotherapeutics company.

Biotechnology · Cambridge$50.0M Post Ipo Secondary
Calithera Biosciences
March 2022

Calithera Biosciences is a pharmaceutical company developing novel small molecule therapeutics for the treatment of cancer.

Biotechnology · South San Francisco$10.0M Post Ipo Equity
Puma Biotechnology
March 2022

Puma Biotechnology acquires and develops innovative products for the treatment of various forms of cancer.

Biotechnology · Los Angeles$10.0M Post Ipo Equity
Pyramid Biosciences
October 2021

Pyramid Biosciences is a provider of biotechnological services.

Biotechnology · Needham$33.5M Series B
Theseus Pharmaceuticals
April 2021

Theseus Pharmaceuticals is a technology-based company.

Biotechnology · New York$100.0M Series B
Flame Biosciences
September 2020

Flame Biosciences is a clinical-stage company focused on therapies for cancer and other inflammatory diseases.

Biotechnology · New York$100.0M Series Unknown
Aimmune Therapeutics
February 2020

Aimmune Therapeutics is a clinical-stage biopharmaceutical company that improves the lives of people with food allergies.

Biotechnology · Brisbane$200.0M Post Ipo Equity
Prevail Therapeutics
March 2019

Prevail Therapeutics is a biotechnology company focused on developing novel gene therapies for patients with Parkinson’s disease.

Biotechnology · New York$50.0M Series B
Engage Therapeutics
September 2017

Engage Therapeutics is a clinical stage pharmaceutical company with a deep-seated passion in epilepsy.

Biopharma · Summit$23.6M Series A

Where Adage Capital Management invests

Biotechnology22
Health Care12
Therapeutics11
Medical7
Pharmaceutical7
Biopharma5

About Adage Capital Management's portfolio

How many companies has Adage Capital Management invested in?▸

Adage Capital Management has invested in 73 companies tracked in our database. The portfolio spans multiple industries and funding stages, from seed-stage startups to late-stage companies.

What industries does Adage Capital Management invest in?▸

Adage Capital Management's top investment sectors include Biotechnology, Health Care, Therapeutics, Medical, Pharmaceutical. The firm invests across 23 different industry categories.

What is Adage Capital Management's largest investment?▸

Among tracked funding rounds, Cerevel Therapeutics received $450.0M in a Post Ipo Equity round. Adage Capital Management's total known invested capital is $10.9B.

What is the average investment size for Adage Capital Management?▸

Adage Capital Management's average investment size is $148.9M across its portfolio of 73 companies.

What are Adage Capital Management's most recent investments?▸

Recent Adage Capital Management portfolio additions include Pepgen, Arvinas, SiMa.ai, Trevi Therapeutics, Tectonic Therapeutic. These companies were founded in 2020 or later.

Reach the founders behind these 73 companies
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