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Alexandria Venture Investments Portfolio Companies

Investor actively backing innovative startups and growth-stage companies across various industries and funding rounds.

Last updated: July 2026

Alexandria Venture Investments Investment Overview

Portfolio Companies
124
Total Invested
$3.8B
Average Investment
$37.7M

Alexandria Venture Investments's Most Recent Investments (2020+)

Company NameFoundedFunding StageAmountCity
Vedana Therapeutics2026Series AUndisclosedSeattle
Autoimmunity BioSolutions2026Seed$2.0MHouston
CREATE Medicines2026Series BUndisclosedCambridge
Kytopen2026Series BUndisclosedCambridge
Fathom Therapeutics2026Series A$31.1MNew York
Neomorph2026Series BUndisclosedSan Diego
Tr1x2025Venture - Series Unknown$50.0MSan Diego
AeroRx Therapeutics2025Series A$21.0MLa Jolla
Dualitas Therapeutics2025Series A$65.0MSan Francisco
Leal Therapeutics2025Series A$30.0MWorcester

Complete List of Alexandria Venture Investments Portfolio Companies (124)

Export
#CompanyStageAmountLocation
1Vedana TherapeuticsSeries AUndisclosedSeattle, United States
2Autoimmunity BioSolutionsSeed$2.0MHouston, United States
3CREATE MedicinesSeries BUndisclosedCambridge, United States
4KytopenSeries BUndisclosedCambridge, United States
5Fathom TherapeuticsSeries A$31.1MNew York, United States
6NeomorphSeries BUndisclosedSan Diego, United States
7Tr1xVenture - Series Unknown$50.0MSan Diego, United States
8AeroRx TherapeuticsSeries A$21.0MLa Jolla, United States
9Dualitas TherapeuticsSeries A$65.0MSan Francisco, United States
10Leal TherapeuticsSeries A$30.0MWorcester, United States
BiotechnologyMedicalPharmaceutical

Vedana Therapeutics is a Seattle biotechnology company developing next-generation antibody therapies for migraine prevention.

Seattle, United States
June 2026
Series A

Founder Contacts

19,000+ verified contacts

Health CareMedicalTherapeutics

Autoimmunity BioSolutions develops a future immuno-corrective treatment that restores healthy immune function.

Houston, United States
May 2026
$2.0M
Seed

Founder Contacts

19,000+ verified contacts

BiotechnologyLife ScienceTherapeutics

CREATE Medicines is a biotech company developing in vivo CAR therapies using mRNA-LNP immune cell programming technology.

Cambridge, United States
May 2026
Series B

Founder Contacts

19,000+ verified contacts

BiotechnologyGeneticsHealth CareLife Science

Kytopen develops genome engineering platforms that enable cell therapy research and manufacturing.

Cambridge, United States
April 2026
Series B

Founder Contacts

19,000+ verified contacts

Artificial Intelligence (AI)BiopharmaBiotechnologyMedicalTherapeutics

Fathom Therapeutics focuses on drug design by harnessing biomolecular motion to develop therapeutics that can reprogram protein function.

New York, United States
April 2026
$31.1M
Series A

Founder Contacts

19,000+ verified contacts

BiotechnologyClinical TrialsHealth CareTherapeutics

Neomorph develops protein degradation therapies targeting diseases not addressed by conventional treatments.

San Diego, United States
April 2026
Series B

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CareLife ScienceMedical

Tr1x is a biotechnology company developing novel cellular immunotherapies for patients with autoimmune and inflammatory diseases.

San Diego, United States
October 2025
$50.0M
Venture - Series Unknown

Founder Contacts

19,000+ verified contacts

Health CarePharmaceuticalWellness

AeroRx Therapeutics is a biopharmaceutical company that developing proprietary, combination products.

La Jolla, United States
October 2025
$21.0M
Series A

Founder Contacts

19,000+ verified contacts

Biotechnology

Dualitas Therapeutics is leading the way in bispecific antibody treatments for inflammatory and immunological (I&I) disorders

San Francisco, United States
September 2025
$65.0M
Series A

Founder Contacts

19,000+ verified contacts

MedicalTherapeutics

Leal Therapeutics develops novel therapeutics for patients.

Worcester, United States
August 2025
$30.0M
Series A

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CareHealth Diagnostics

GeneCentric Therapeutics develops and commercializes molecular diagnostic tests for oncologists and patients.

Durham, United States
June 2025
$8.0M
Series C

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth DiagnosticsMedicalTherapeutics

Remedy Plan is a pre-clinical cancer therapeutics company developing first-in-class small molecule drugs that differentiate cancer cells.

Gaithersburg, United States
May 2025
$18.0M
Venture - Series Unknown

Founder Contacts

19,000+ verified contacts

Animal FeedBiotechnologyLife ScienceLivestock

Hoofprint Biome is a biotechnology company that develops probiotics that improve the sustainability of ruminant livestock production.

Raleigh, United States
April 2025
$15.0M
Series A

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CareLife ScienceTherapeutics

Garuda Therapeutics develops off-the-shelf hematopoietic stem cell therapies to treat severe and life-threatening diseases.

Cambridge, United States
March 2025
$50.0M
Series A

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CareMedicalPharmaceutical

Ten63 Therapeutics is a venture-backed startup developing durable therapeutics against some of the world's most lethal diseases.

Durham, United States
December 2024
Series A

Founder Contacts

19,000+ verified contacts

BiopharmaBiotechnologyHealth CareHealth Diagnostics

Pleno is a biotechnology company that aims speeding up disease diagnosis and treatment.

San Diego, United States
December 2024
$25.0M
Series B

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CareTherapeutics

Jupiter BioVentures is a creation engine company that focuses on de-risking early-stage projects.

Delaware City, United States
November 2024
$70.0M
Venture - Series Unknown

Founder Contacts

19,000+ verified contacts

BioinformaticsBiopharmaBiotechnology

TRex Bio is a biotechnology company that treats diseases like cancer, fibrotic by studying human tissues.

South San Francisco, United States
November 2024
$84.0M
Series B

Founder Contacts

19,000+ verified contacts

BiotechnologyTherapeutics

CrossBridge Bio operates as a biotechnology company.

Houston, United States
November 2024
$10.0M
Seed

Founder Contacts

19,000+ verified contacts

BiotechnologyTherapeutics

Archon is a biotechnology firm that promotes next-generation antibody treatments through AI and computational protein design.

Washington, United States
October 2024
$20.0M
Seed

Founder Contacts

19,000+ verified contacts

BiotechnologyPharmaceuticalTherapeutics

Passkey Therapeutics is pioneering a new class of medicines, Synergistic Multifunctional Therapeutics (SMThs).

Cambridge, United States
October 2024
$20.0M
Seed

Founder Contacts

19,000+ verified contacts

Food ProcessingIntellectual PropertyOrganic Food

5Metis is a new pure-play discovery company for crop health.

Durham, United States
April 2024
$5.5M
Series A

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth Care

Early stage biotechnology company

Germantown, United States
December 2023
$29.9M
Venture - Series Unknown

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CarePharmaceutical

ROME Therapeutics is developing novel therapies for cancer and autoimmune diseases by harnessing the power of the repeatome.

Cambridge, United States
September 2023
$72.0M
Series B

Founder Contacts

19,000+ verified contacts

Health CareMedicalNeuroscienceTherapeutics

Arialys Therapeutics is a pre-clinical stage company that develops auto-antibody focusing on neuroscience.

La Jolla, United States
September 2023
$58.0M
Seed

Founder Contacts

19,000+ verified contacts

Showing 1-25 of 124 portfolio companies

Frequently Asked Questions About Alexandria Venture Investments

How many companies has Alexandria Venture Investments invested in?

Alexandria Venture Investments has invested in 124 companies tracked in our database. The portfolio spans multiple industries and funding stages, from seed-stage startups to late-stage companies.

What industries does Alexandria Venture Investments invest in?

Alexandria Venture Investments's top investment sectors include Biotechnology, Health Care, Therapeutics, Medical, Pharmaceutical. The firm invests across 19 different industry categories.

What is Alexandria Venture Investments's largest investment?

Among tracked funding rounds, TRex Bio received $84.0M in a Series B round. Alexandria Venture Investments's total known invested capital is $3.8B.

What is the average investment size for Alexandria Venture Investments?

Alexandria Venture Investments's average investment size is $37.7M across its portfolio of 124 companies.

What are Alexandria Venture Investments's most recent investments?

Recent Alexandria Venture Investments portfolio additions include Vedana Therapeutics, Autoimmunity BioSolutions, CREATE Medicines, Kytopen, Fathom Therapeutics. These companies were founded in 2020 or later.

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