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ARCH Venture Partners Portfolio Companies

Investor actively backing innovative startups and growth-stage companies across various industries and funding rounds.

Last updated: June 2026

ARCH Venture Partners Investment Overview

Portfolio Companies
156
Total Invested
$14.3B
Average Investment
$119.8M

ARCH Venture Partners's Most Recent Investments (2020+)

Company NameFoundedFunding StageAmountCity
CREATE Medicines2026Series BUndisclosedCambridge
Moleculent2026Series A$26.0MSolna
Maze Therapeutics2026Post-IPO EquityUndisclosedSouth San Francisco
Lightcast Discovery2026Venture - Series UnknownUndisclosedCambridge
Seaport Therapeutics2026Grant$15.0MBoston
Kardigan2025Series B$254.0MSouth San Francisco
Ollin Biosciences2025Series A$100.0MAustin
Dewpoint Therapeutics2025Series D$59.1MBoston
Treeline Biosciences2025Series A$200.0MWatertown
Tenvie Therapeutics2025Series A$200.0MSouth San Francisco

Complete List of ARCH Venture Partners Portfolio Companies (156)

Export
#CompanyStageAmountLocation
1CREATE MedicinesSeries BUndisclosedCambridge, United States
2MoleculentSeries A$26.0MSolna, Sweden
3Maze TherapeuticsPost-IPO EquityUndisclosedSouth San Francisco, United States
4Lightcast DiscoveryVenture - Series UnknownUndisclosedCambridge, United Kingdom
5Seaport TherapeuticsGrant$15.0MBoston, United States
6KardiganSeries B$254.0MSouth San Francisco, United States
7Ollin BiosciencesSeries A$100.0MAustin, United States
8Dewpoint TherapeuticsSeries D$59.1MBoston, United States
9Treeline BiosciencesSeries A$200.0MWatertown, United States
10Tenvie TherapeuticsSeries A$200.0MSouth San Francisco, United States
BiotechnologyLife ScienceTherapeutics

CREATE Medicines is a biotech company developing in vivo CAR therapies using mRNA-LNP immune cell programming technology.

Cambridge, United States
May 2026
Series B

Founder Contacts

19,000+ verified contacts

Biotechnology

Moleculent is the Biotechnology Research company.

Solna, Sweden
April 2026
$26.0M
Series A

Founder Contacts

19,000+ verified contacts

BiopharmaBiotechnologyGeneticsTherapeutics

Maze Therapeutics is a biotechnology company that develops precision medicines for renal, cardiovascular, and metabolic diseases.

South San Francisco, United States
April 2026
Post-IPO Equity

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CareMedical

Lightcast uses a microfluidic platform to make advances towards unique clinical approaches, new therapies, and innovative products.

Cambridge, United Kingdom
April 2026
Venture - Series Unknown

Founder Contacts

19,000+ verified contacts

BiopharmaBiotechnologyTherapeutics

Seaport Therapeutics is a clinical-stage biopharmaceutical company that develops neuropsychiatric medicines.

Boston, United States
March 2026
$15.0M
Grant

Founder Contacts

19,000+ verified contacts

BiopharmaHealth CareMedical

Kardigan develops personalized medicines using AI and data to target and treat the root causes of cardiovascular diseases.

South San Francisco, United States
October 2025
$254.0M
Series B

Founder Contacts

19,000+ verified contacts

BiopharmaMedicalTherapeutics

Ollin Biosciences operates as a clinical-stage biopharmaceutical company.

Austin, United States
September 2025
$100.0M
Series A

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CareLife ScienceMedicalTherapeutics

Dewpoint Therapeutics is a biotech company developing a drug platform that targets biomolecular condensates.

Boston, United States
September 2025
$59.1M
Series D

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CareLife ScienceMedicalPrecision Medicine

Treeline Biosciences is a biotech company building transformative precision medicines for patients with cancer and other serious conditions.

Watertown, United States
September 2025
$200.0M
Series A

Founder Contacts

19,000+ verified contacts

BiotechnologyMedicalNeuroscienceTherapeutics

Tenvie Therapeutics is a biotechnology company that transforms the treatment of neurological diseases through engineered small molecules.

South San Francisco, United States
January 2025
$200.0M
Series A

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CareOncologyTherapeutics

Akamis Bio is a clinical-stage oncology company.

Abingdon, United Kingdom
December 2024
$60.0M
Series A

Founder Contacts

19,000+ verified contacts

BiotechnologyCommercialHealth Care

Bit.bio specializes in the fields of coding and biology that determine the identity of every human cell.

Cambridge, United Kingdom
December 2024
$30.0M
Venture - Series Unknown

Founder Contacts

19,000+ verified contacts

BiopharmaLife ScienceTherapeutics

City Therapeutics is a biopharmaceutical company focused on developing next-generation small interfering RNAs.

Cambridge, United States
October 2024
$135.0M
Series A

Founder Contacts

19,000+ verified contacts

Elder CareHealth CareHealth DiagnosticsMental Health

Rippl Care is a mental health company committed to assisting seniors who suffer from dementia and other neurocognitive disorders.

Seattle, United States
October 2024
$23.0M
Series A

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth DiagnosticsLife ScienceMedical

Vilya is a biotechnology company developing a novel class of drugs that precisely target the biology of disease.

Seattle, United States
June 2024
$21.0M
Series A

Founder Contacts

19,000+ verified contacts

BiotechnologyMedicalTherapeutics

Slingshot Biosciences develops next-generation synthetic cells for diagnostics and therapeutics.

Emeryville, United States
April 2024
$15.0M
Series A

Founder Contacts

19,000+ verified contacts

NeuroscienceWellness

Over millions and millions of years, a collection of reward systems

Boulder, United States
February 2024
$26.0M
Seed

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CareLife SciencePharmaceutical

Proniras focuses on development of a new parenteral medical countermeasure (MCM) to treat seizures and brain injury.

Seattle, United States
February 2024
$4.7M
Series B

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CarePharmaceuticalTherapeutics

Basking Biosciences is to commercialize technology developed at Duke and Ohio State Universities.

Durham, United States
January 2024
$55.0M
Series A

Founder Contacts

19,000+ verified contacts

Health CareHome Health CareWellness

Accompany Health provides comprehensive in-home care to patients who live in sometimes underserved regions.

Bethesda, United States
January 2024
$56.0M
Series A

Founder Contacts

19,000+ verified contacts

BiotechnologyGeneticsMedical

Tome Biosciences is a biotechnology company that develops programmable gene insertion technology.

Watertown, United States
December 2023
$213.0M
Series A

Founder Contacts

19,000+ verified contacts

BiotechnologyMedicalPharmaceutical

Magnet Biomedicine is a biotechnology research platform specializing in discovering true molecular glues.

Cambridge, United States
September 2023
$50.0M
Series A

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CarePharmaceutical

ROME Therapeutics is developing novel therapies for cancer and autoimmune diseases by harnessing the power of the repeatome.

Cambridge, United States
September 2023
$72.0M
Series B

Founder Contacts

19,000+ verified contacts

BiopharmaBiotechnologyHealth CareOncologyTherapeutics

OncoResponse is an immuno-oncology biotech company developing cancer immunotherapies leveraging human immune system responses.

Seattle, United States
May 2023
$14.0M
Series D

Founder Contacts

19,000+ verified contacts

Health CareHospitalOutpatient Care

Recuro Health offers a holistic suite of virtual care services and supplemental benefits.

Richardson, United States
April 2023
$47.0M
Series B

Founder Contacts

19,000+ verified contacts

Showing 1-25 of 156 portfolio companies

Frequently Asked Questions About ARCH Venture Partners

How many companies has ARCH Venture Partners invested in?

ARCH Venture Partners has invested in 156 companies tracked in our database. The portfolio spans multiple industries and funding stages, from seed-stage startups to late-stage companies.

What industries does ARCH Venture Partners invest in?

ARCH Venture Partners's top investment sectors include Biotechnology, Health Care, Therapeutics, Medical, Life Science. The firm invests across 19 different industry categories.

What is ARCH Venture Partners's largest investment?

Among tracked funding rounds, Kardigan received $254.0M in a Series B round. ARCH Venture Partners's total known invested capital is $14.3B.

What is the average investment size for ARCH Venture Partners?

ARCH Venture Partners's average investment size is $119.8M across its portfolio of 156 companies.

What are ARCH Venture Partners's most recent investments?

Recent ARCH Venture Partners portfolio additions include CREATE Medicines, Moleculent, Maze Therapeutics, Lightcast Discovery, Seaport Therapeutics. These companies were founded in 2020 or later.

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