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Entrepreneurs First — Portfolio

Investor actively backing innovative startups and growth-stage companies across various industries and funding rounds.

394
Companies
$4.0B
Total invested
$10.0M
Avg. check
54
Industries
Artificial Intelligence (AI) 15Software 9Machine Learning 4Health Care 3Compliance 3Enterprise Software 3+48 more
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Portfolio companies

Showing 1–24 of 394
Clarity Care AI
October 2026

Clarity Care AI provides healthcare AI software for documentation, care coordination, analytics, and workflow automation.

Artificial Intelligence (AI) · San Francisco$16.3M Series A
Opply
October 2026

Opply digitizes supply chain for food and beverage brands globally.

E-Commerce · London$7.5M Venture - Series Unknown
Scarlet
October 2026

Scarlet assesses artificial intelligence medical devices and medical software for compliance with applicable regulatory requirements.

Artificial Intelligence (AI) · London$50.0M Series B
IRIDIUM CREDIT
October 2026

The verification infrastructure for invoice finance.

Artificial Intelligence (AI) · New York$3.0M Seed
Right-Hand Cybersecurity
October 2026

Right-Hand Cybersecurity helps enterprises upgrade their Security Awareness with Agentic AI.

Artificial Intelligence (AI) · Lewes$3.0M Venture - Series Unknown
Omini
September 2026

Omini develops a biosensor platform that allows the simultaneous detection of multiple biomarkers.

Biotechnology · Paris$150K Seed
ByteAsk
September 2026

Derisk your AI agents

San Francisco$1.0M Pre-Seed
Open Cosmos
September 2026

Open Cosmos is a space technology company that designs, builds, and operates low-earth orbit satellites.

Aerospace · Didcot$346.4M Series C
Vivid Machines
September 2026

Vivid Machines is a startup company that revolutionizes agricultural production to help fruit and vegetable farmers produce more food.

AgTech · Toronto$1.2M Grant
HelmGuard AI
September 2026

HelmGuard develops an AI-driven trust infrastructure platform for security, compliance, and third-party risk management.

Artificial Intelligence (AI) · London$7.3M Seed
CloudNC
September 2026

CloudNC develops advanced software that enables factories to autonomously manufacture precision parts.

Artificial Intelligence (AI) · London$20.0M Series B
Jack & Jill AI
September 2026

Meet Jack and Jill. Two AI agents that introduce remarkable people to remarkable companies.

Artificial Intelligence (AI) · London$40.6M Series A
Pharosyn
September 2026

Pharosyn is an AI-powered competitive intelligence platform for the pharma and biotech sectors.

Newark$3.0M Seed
Phantasma Labs
September 2026

AI-based production planning software delivering 200× faster, 30% better plans. No big data. ROI in just 3–6 months.

Artificial Intelligence (AI) · Berlin$3.0M Venture - Series Unknown
OLIX
August 2026

OLIX designs optical AI accelerators that use light-based processors for training and inference on large models.

Artificial Intelligence (AI) · London$312.0M Series B
EverSettled
July 2026

EverSettled provides software and tools to guide families through probate.

Information Technology · San Francisco$5.0M Seed
Juno Bio
July 2026

Juno Bio is a biotechnology company that uses machine learning and bioinformatics to analyse and predict how best to manipulate microbiomes.

Bioinformatics · London$3.8M Venture - Series Unknown
Hadean
July 2026

Hadean are a venture backed startup, reimagining distributed, spatial and scalable computing for web 3.0 and the metaverse.

Artificial Intelligence (AI) · London$114K Grant
Automata
June 2026

Automata is a lab automation company offering the LINQ platform to streamline workflows and boost laboratory efficiency.

Artificial Intelligence (AI) · LondonSeries C
Uncovr
June 2026

Uncovr is a surgical intelligence platform designed to automatically turn operating room videos into structured clinical reports and billing

Artificial Intelligence (AI) · San Francisco$7.0M Seed
Freshflow
June 2026

Freshflow is harnessing AI to build the food supply chain technology of the future and tackle global food waste.

Artificial Intelligence (AI) · Berlin$10.0M Series A
AUDIOGEN
May 2026

An applied research lab exploring new modes of music and audio creation.

Artificial Intelligence (AI) · London$2.2M Seed
Certo
May 2026

Certo is an agentic AI company that offers a product compliance platform for regulatory management.

Agentic AI · San Francisco$4.0M Seed
Level Nine
March 2026

Level Nine specializes in bio-nanotechnology and quantum chemistry, developing next-generation catalysts known as nanozymes.

Chemical · Berlin$4.6M Seed

Where Entrepreneurs First invests

Artificial Intelligence (AI)15
Software9
Machine Learning4
Health Care3
Compliance3
Enterprise Software3

About Entrepreneurs First's portfolio

How many companies has Entrepreneurs First invested in?▸

Entrepreneurs First has invested in 394 companies tracked in our database. The portfolio spans multiple industries and funding stages, from seed-stage startups to late-stage companies.

What industries does Entrepreneurs First invest in?▸

Entrepreneurs First's top investment sectors include Artificial Intelligence (AI), Software, Machine Learning, Health Care, Compliance. The firm invests across 54 different industry categories.

What is Entrepreneurs First's largest investment?▸

Among tracked funding rounds, Open Cosmos received $346.4M in a Series C round. Entrepreneurs First's total known invested capital is $4.0B.

What is the average investment size for Entrepreneurs First?▸

Entrepreneurs First's average investment size is $10.0M across its portfolio of 394 companies.

What are Entrepreneurs First's most recent investments?▸

Recent Entrepreneurs First portfolio additions include Clarity Care AI, Opply, Scarlet, IRIDIUM CREDIT, Right-Hand Cybersecurity. These companies were founded in 2020 or later.

Reach the founders behind these 394 companies
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