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Janus Henderson Investors — Portfolio

Investor actively backing innovative startups and growth-stage companies across various industries and funding rounds.

227
Companies
$31.3B
Total invested
$160.4M
Avg. check
42
Industries
Biotechnology 18Health Care 11Therapeutics 11Biopharma 8Life Science 7Oncology 4+36 more
Founder contacts

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Portfolio companies

Showing 124 of 227
Xos Trucks
September 2025

Xos Trucks specializes in the field of manufacturing fully electric commercial vehicles.

Business Development · Los Angeles$2.4M Post-IPO Equity
Aktis Oncology
September 2024

Aktis Oncology is a biotechnology company that designs and develops novel class radiopharmaceuticals.

Biotechnology · Boston$175.0M Series B
Pepgen
September 2025

PepGen is empowering nucleic acid therapeutics to go the distance.

Biotechnology · Oxford$115.0M Post-IPO Equity
Monopar
September 2025

Monopar Therapeutics is an emerging biopharmaceutical company focused on developing orphan oncology compounds.

Biopharma · Wilmette$135.0M Post-IPO Equity
Ventyx Biosciences
September 2024

Ventyx is a biopharmaceutical company focused on advancing oral therapies for patients living with autoimmune and inflammatory disorders.

Biopharma · San Diego$27.0M Post-IPO Equity
Korsana Biosciences
September 2025

Korsana Biosciences develops THETA-enabled antibody therapies for neurodegenerative diseases including Alzheimer’s.

Biopharma · Waltham$150.0M Series A
Loadsmart
September 2022

Loadsmart is the end-to-end AI freight platform for shippers with embedded operational services.

Enterprise Software · ChicagoUndisclosed
Avidity Biosciences
September 2025

Synapse Energy Economics is a consulting firm providing economic and policy analysis for the electric power sector.

Biotechnology · San Diego$690.0M Post-IPO Equity
QuantumScape
August 2023

QuantumScape develops solid-state lithium-metal batteries for electric vehicles and other energy storage applications.

Automotive · San Jose$300.0M Post-IPO Equity
Bigfoot Biomedical
August 2022

Bigfoot Biomedical is a medical device company changing diabetes care for people with insulin-requiring diabetes.

Artificial Intelligence (AI) · MilpitasConvertible Note
Inspirato
August 2024

Inspirato is a luxury travel and lifestyle subscription company.

Lifestyle · Denver$4.6M Post-IPO Equity
Compass Therapeutics
August 2025

Compass Therapeutics is a biopharmaceutical company that focuses on drugging the immune system to treat human diseases.

Biopharma · Boston$120.0M Post-IPO Equity
Annexon Biosciences
July 2026

Annexon Biosciences is a biotech company, discovering and developing novel therapeutics for neurodegenerative and autoimmune disorders.

Biotechnology · South San Francisco$50.0M Post-IPO Debt
Day One Biopharmaceuticals
July 2024

Day One Biopharmaceuticals develops targeted therapies to treat people with life-threatening diseases.

Biopharma · South San Francisco$175.0M Post-IPO Equity
Claris Biotherapeutics
July 2026

Claris Biotherapeutics develops biologic therapies for corneal diseases and other disorders affecting the ocular surface.

Biopharma · Jersey City$118.0M Series B
Wallbox
July 2026

Wallbox is a technology company that provides electric vehicle charging and energy management solutions.

Automotive · Barcelona$4.6M Post-IPO Equity
Scorpion Therapeutics
July 2024

Scorpion Therapeutics is a clinical-stage oncology company that specializes in precision medicine for cancer patients.

Biotechnology · Boston$150.0M Series C
Draig Therapeutics
July 2026

Draig Therapeutics is a clinical-stage biopharmaceutical company that develops investigational therapies for neuropsychiatric disorders.

Biopharma · Cardiff$65.0M Series B
Caribou Biosciences
July 2023

Caribou Biosciences is a biotechnology company that develops CRISPR technologies and allogenic cell therapies for oncology.

Biotechnology · Berkeley$125.0M Post-IPO Equity
Neurogene
July 2026

Neurogene is a developer of genetic medicines intended to improve patient outcomes for neurological disorders.

Biotechnology · New York$125.0M Post-IPO Equity
Element Biosciences
June 2026

Element Biosciences develops genomic sequencing and multiomics technologies used in drug discovery, and diagnostic applications.

Biotechnology · San DiegoSeries E
Tango Therapeutics
June 2026

Tango Therapeutics is a biotechnology company that is developing next generation cancer therapies.

Biotechnology · Cambridge$600.0M Post-IPO Equity
Equillium
March 2026

Equillium is a biotechnology company that develops products for autoimmune and inflammatory disorders with an unmet medical need.

Biopharma · La Jolla$35.0M Post Ipo Equity
Longeveron
March 2026

Longeveron is a biotechnology company that focuses on developing cellular therapies for chronic aging-related and life-threatening diseases.

Biotechnology · Miami$30.0M Post Ipo Equity

Where Janus Henderson Investors invests

Biotechnology18
Health Care11
Therapeutics11
Biopharma8
Life Science7
Oncology4

About Janus Henderson Investors's portfolio

How many companies has Janus Henderson Investors invested in?

Janus Henderson Investors has invested in 227 companies tracked in our database. The portfolio spans multiple industries and funding stages, from seed-stage startups to late-stage companies.

What industries does Janus Henderson Investors invest in?

Janus Henderson Investors's top investment sectors include Biotechnology, Health Care, Therapeutics, Biopharma, Life Science. The firm invests across 42 different industry categories.

What is Janus Henderson Investors's largest investment?

Among tracked funding rounds, Avidity Biosciences received $690.0M in a Post-IPO Equity round. Janus Henderson Investors's total known invested capital is $31.3B.

What is the average investment size for Janus Henderson Investors?

Janus Henderson Investors's average investment size is $160.4M across its portfolio of 227 companies.

What are Janus Henderson Investors's most recent investments?

Recent Janus Henderson Investors portfolio additions include Xos Trucks, Aktis Oncology, Pepgen, Monopar, Ventyx Biosciences. These companies were founded in 2020 or later.

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