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Janus Henderson Investors Portfolio Companies

Investor actively backing innovative startups and growth-stage companies across various industries and funding rounds.

Last updated: July 2026

Janus Henderson Investors Investment Overview

Portfolio Companies
121
Total Invested
$12.5B
Average Investment
$129.0M

Janus Henderson Investors's Most Recent Investments (2020+)

Company NameFoundedFunding StageAmountCity
Tango Therapeutics2026Post-IPO EquityUndisclosedCambridge
Jade Biosciences2026Post-IPO EquityUndisclosedWaltham
ALX Oncology2026Post-IPO DebtUndisclosedSan Francisco
Lycia Therapeutics2026Series DUndisclosedSouth San Francisco
Helus Pharma2026Post-IPO EquityUndisclosedToronto
Definium Therapeutics2026Post-IPO EquityUndisclosedNew York
Triveni Bio2026Series C$115.0MWatertown
Enliven Therapeutics2026Post-IPO EquityUndisclosedBoulder
Parabilis Medicines2026Post-IPO Equity$305.0MCambridge
Shattuck Labs2026Post-IPO EquityUndisclosedAustin

Complete List of Janus Henderson Investors Portfolio Companies (121)

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#CompanyStageAmountLocation
1Tango TherapeuticsPost-IPO EquityUndisclosedCambridge, United States
2Jade BiosciencesPost-IPO EquityUndisclosedWaltham, United States
3ALX OncologyPost-IPO DebtUndisclosedSan Francisco, United States
4Lycia TherapeuticsSeries DUndisclosedSouth San Francisco, United States
5Helus PharmaPost-IPO EquityUndisclosedToronto, Canada
6Definium TherapeuticsPost-IPO EquityUndisclosedNew York, United States
7Triveni BioSeries C$115.0MWatertown, United States
8Enliven TherapeuticsPost-IPO EquityUndisclosedBoulder, United States
9Parabilis MedicinesPost-IPO Equity$305.0MCambridge, United States
10Shattuck LabsPost-IPO EquityUndisclosedAustin, United States
BiotechnologyHealth CareMedicalTherapeutics

Tango Therapeutics is a biotechnology company that is developing next generation cancer therapies.

Cambridge, United States
June 2026
Post-IPO Equity

Founder Contacts

19,000+ verified contacts

BiopharmaHealth CareTherapeutics

Jade Biosciences is developing transformative therapies to redefine the standard of care for inflammation and immunology indications.

Waltham, United States
June 2026
Post-IPO Equity

Founder Contacts

19,000+ verified contacts

BiopharmaBiotechnologyHealth CareLife ScienceOncologyTherapeutics

ALX Oncology is a preclinical stage biotechnology company developing innovative immuno-oncology therapies for cancer.

San Francisco, United States
June 2026
Post-IPO Debt

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CareLife Science

Lycia Therapeutics is a biotechnology company that focuses on developing technology that utilizes lysosome-targeting chimeras.

South San Francisco, United States
June 2026
Series D

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CareMental HealthNeurosciencePharmaceutical

Helus Pharma is a biopharmaceutical company that develops psychedelic therapeutics for mental health conditions.

Toronto, Canada
June 2026
Post-IPO Equity

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CarePharmaceuticalTherapeutics

Definium Therapeutics provides psychedelic-inspired medicines and therapies for substance abuse disorders and other mental illnesses.

New York, United States
June 2026
Post-IPO Equity

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CareMedicalTherapeutics

Triveni Bio is a biotechnology company that develops antibody-based therapeutics for immunological and inflammatory diseases.

Watertown, United States
June 2026
$115.0M
Series C

Founder Contacts

19,000+ verified contacts

BiotechnologyLife ScienceOncologyTherapeutics

Enliven Therapeutics is a precision oncology company developing small molecule therapies to extend and improve patient lives.

Boulder, United States
June 2026
Post-IPO Equity

Founder Contacts

19,000+ verified contacts

BiopharmaBiotechnologyHealth CareLife ScienceMedicalPharmaceuticalPrecision Medicine

Parabilis Medicines is a Grupo Bugio is a biopharmaceutical firm that specializes in creating medicines.

Cambridge, United States
June 2026
$305.0M
Post-IPO Equity

Founder Contacts

19,000+ verified contacts

BiopharmaBiotechnologyLife Science

Shattuck Labs is a biotechnology company that provides novel class biologic medicines for the treatment of cancer and autoimmune disease.

Austin, United States
June 2026
Post-IPO Equity

Founder Contacts

19,000+ verified contacts

BiopharmaBiotechnologyHealth Care

Ocugen is a biotechnology company that develops novel gene and cell therapies to improve health and patient outcomes.

Malvern, United States
May 2026
Post-IPO Debt

Founder Contacts

19,000+ verified contacts

AutomotiveCharging InfrastructureCleanTechConsumer ElectronicsElectric VehicleIndustrial ManufacturingManufacturing

Wallbox is a technology company that provides electric vehicle charging and energy management solutions.

Barcelona, Spain
April 2026
Post-IPO Debt

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CareMedicalNeurosciencePharmaceutical

Climb Bio occurs when the immune system mistakenly attacks the body's tissues and can result in permanent organ damage or even death.

Redmond, United States
April 2026
Post-IPO Equity

Founder Contacts

19,000+ verified contacts

BiopharmaBiotechnologyGeneticsTherapeutics

Maze Therapeutics is a biotechnology company that develops precision medicines for renal, cardiovascular, and metabolic diseases.

South San Francisco, United States
April 2026
Post-IPO Equity

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CareTherapeutics

Ray Therapeutics is a biotech company that develops optogenetic gene therapies for patients with blinding diseases.

San Diego, United States
April 2026
Series B

Founder Contacts

19,000+ verified contacts

Health CareMedicalMedical DeviceWellness

Calyxo is a medical device company that improves kidney stone treatment through specialized urology technologies.

Pleasanton, United States
April 2026
$28.3M
Series F

Founder Contacts

19,000+ verified contacts

BiotechnologyGeneticsHealth CareMedical

Solid Biosciences is a life science company that conducts research for the treatment of Duchenne muscular dystrophy.

Charlestown, United States
March 2026
$240.0M
Post Ipo Equity

Founder Contacts

19,000+ verified contacts

BiopharmaBiotechnologyLife Science

Equillium is a biotechnology company that develops products for autoimmune and inflammatory disorders with an unmet medical need.

La Jolla, United States
March 2026
$35.0M
Post Ipo Equity

Founder Contacts

19,000+ verified contacts

BiotechnologyLife ScienceMedicalTherapeutics

Longeveron is a biotechnology company that focuses on developing cellular therapies for chronic aging-related and life-threatening diseases.

Miami, United States
March 2026
$30.0M
Post Ipo Equity

Founder Contacts

19,000+ verified contacts

BiotechnologyPharmaceuticalTherapeutics

Kailera Therapeutics develops next-generation injectable and oral therapies for chronic weight management.

Waltham, United States
October 2025
$600.0M
Series B

Founder Contacts

19,000+ verified contacts

Health CareMedicalMedical DeviceTherapeutics

Galvanize is a biomedical platform company that provides therapeutic products and services to deliver healthcare solutions.

San Carlos, United States
September 2025
$100.0M
Series C

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CareLife ScienceMedical

Bambusa Therapeutics operates as biotechnology company.

Boston, United States
February 2025
$90.0M
Series A

Founder Contacts

19,000+ verified contacts

BiopharmaBiotechnologyHealth CareMedical

Attralus is a biopharmaceutical company focusing on creating transformative medicines to improve the lives of patients.

San Francisco, United States
February 2024
$56.0M
Series B

Founder Contacts

19,000+ verified contacts

BioinformaticsBiotechnologyGeneticsLife Science

Parse Biosciences is a biotechnology startup company that develops single-cell sequencing kit solutions for researchers.

Seattle, United States
December 2023
$50.0M
Series C

Founder Contacts

19,000+ verified contacts

BiotechnologyGeneticsHealth Care

TwinStrand Biosciences develops and commercializes the duplex sequencing technology for DNA sequencing.

Seattle, United States
June 2023
$10.3M
Venture - Series Unknown

Founder Contacts

19,000+ verified contacts

Showing 1-25 of 121 portfolio companies

Frequently Asked Questions About Janus Henderson Investors

How many companies has Janus Henderson Investors invested in?

Janus Henderson Investors has invested in 121 companies tracked in our database. The portfolio spans multiple industries and funding stages, from seed-stage startups to late-stage companies.

What industries does Janus Henderson Investors invest in?

Janus Henderson Investors's top investment sectors include Biotechnology, Health Care, Therapeutics, Medical, Life Science. The firm invests across 22 different industry categories.

What is Janus Henderson Investors's largest investment?

Among tracked funding rounds, Kailera Therapeutics received $600.0M in a Series B round. Janus Henderson Investors's total known invested capital is $12.5B.

What is the average investment size for Janus Henderson Investors?

Janus Henderson Investors's average investment size is $129.0M across its portfolio of 121 companies.

What are Janus Henderson Investors's most recent investments?

Recent Janus Henderson Investors portfolio additions include Tango Therapeutics, Jade Biosciences, ALX Oncology, Lycia Therapeutics, Helus Pharma. These companies were founded in 2020 or later.

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