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Janus Henderson Investors — Portfolio

Investor actively backing innovative startups and growth-stage companies across various industries and funding rounds.

229
Companies
$34.7B
Total invested
$151.4M
Avg. check
24
Industries
Biotechnology 21Health Care 15Therapeutics 12Life Science 9Medical 6Biopharma 6+18 more
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Portfolio companies

Showing 1–24 of 229
Star Therapeutics
October 2026

Star Therapeutics mission is to develop therapies for as many diseases as possible for millions of patients.

Health Care · South San Francisco$200.0M Venture - Series Unknown
Epicrispr Biotechnologies
October 2026

Epicrispr Biotechnologies is a biotechnology enterprise that focuses on epigenetic engineering.

Biotechnology · South San Francisco$8.0M Grant
Vaxcyte
October 2026

Vaxcyte focuses on developing vaccines designed to prevent or treat some of the most common and deadly infectious diseases worldwide.

Biopharma · San Carlos$575.0M Post-IPO Debt
Pyxis Oncology
September 2026

Pyxis Oncology is a biotechnology firm that develops antibody therapeutics intended to promote the body's immune response to cancer.

Biotechnology · Boston$110.0M Post-IPO Equity
AN2 Therapeutics
September 2026

AN2 Therapeutics develops small-molecule medicines from boron chemistry for infectious diseases, hematologic disorders, and oncology.

Biotechnology · Menlo Park$40.0M Grant
Tare
September 2026

Tare uses AI and tokenization to change the entire credit lifecycle.

Artificial Intelligence (AI) · Brooklyn$13.3M Seed
Tyra Biosciences
September 2026

Tyra Biosciences is a biotechnology company targeting new pathways of acquired resistance in oncology with purpose-built drugs.

Biotechnology · Carlsbad$400.0M Post-IPO Equity
Helus Pharma
September 2026

Helus Pharma is a biopharmaceutical company that develops psychedelic therapeutics for mental health conditions.

Biotechnology · Toronto$50.0M Post-IPO Equity
Encoded Therapeutics
September 2026

Encoded Therapeutics is a biotechnology company developing genetic medicines for neurological disorders and other diseases.

Biotechnology · South San Francisco$275.0M Series F
Annexon Biosciences
July 2026

Annexon Biosciences is a biotech company, discovering and developing novel therapeutics for neurodegenerative and autoimmune disorders.

Biotechnology · South San Francisco$50.0M Post-IPO Debt
Claris Biotherapeutics
July 2026

Claris Biotherapeutics develops biologic therapies for corneal diseases and other disorders affecting the ocular surface.

Biopharma · Jersey City$118.0M Series B
Draig Therapeutics
July 2026

Draig Therapeutics is a clinical-stage biopharmaceutical company that develops investigational therapies for neuropsychiatric disorders.

Biopharma · Cardiff$65.0M Series B
Wallbox
July 2026

Wallbox is a technology company that provides electric vehicle charging and energy management solutions.

Automotive · Barcelona$4.6M Post-IPO Equity
Neurogene
July 2026

Neurogene is a developer of genetic medicines intended to improve patient outcomes for neurological disorders.

Biotechnology · New York$125.0M Post-IPO Equity
4D Molecular Therapeutics
June 2026

4D Molecular Therapeutics designs, develops, and commercializes transformative gene therapeutic products for unmet medical conditions.

Biotechnology · Emeryville$200.0M Post-IPO Debt
ALX Oncology
June 2026

ALX Oncology is a preclinical stage biotechnology company developing innovative immuno-oncology therapies for cancer.

Biopharma · San Francisco$10.0M Post-IPO Debt
Lycia Therapeutics
June 2026

Lycia Therapeutics is a biotechnology company that focuses on developing technology that utilizes lysosome-targeting chimeras.

Biotechnology · South San Francisco$75.0M Series D
Definium Therapeutics
June 2026

Definium Therapeutics provides psychedelic-inspired medicines and therapies for substance abuse disorders and other mental illnesses.

Biotechnology · New York$805.0M Post-IPO Equity
Triveni Bio
June 2026

Triveni Bio is a biotechnology company that develops antibody-based therapeutics for immunological and inflammatory diseases.

Biotechnology · Watertown$65.0M Series C
Enliven Therapeutics
June 2026

Enliven Therapeutics is a precision oncology company developing small molecule therapies to extend and improve patient lives.

Biotechnology · Boulder$460.0M Post-IPO Equity
Parabilis Medicines
June 2026

Parabilis Medicines is a Grupo Bugio is a biopharmaceutical firm that specializes in creating medicines.

Biopharma · Cambridge$75.0M Post-IPO Equity
Equillium
March 2026

Equillium is a biotechnology company that develops products for autoimmune and inflammatory disorders with an unmet medical need.

Biopharma · La Jolla$35.0M Post Ipo Equity
Longeveron
March 2026

Longeveron is a biotechnology company that focuses on developing cellular therapies for chronic aging-related and life-threatening diseases.

Biotechnology · Miami$30.0M Post Ipo Equity
Solid Biosciences
March 2026

Solid Biosciences is a life science company that conducts research for the treatment of Duchenne muscular dystrophy.

Biotechnology · Charlestown$240.0M Post Ipo Equity

Where Janus Henderson Investors invests

Biotechnology21
Health Care15
Therapeutics12
Life Science9
Medical6
Biopharma6

About Janus Henderson Investors's portfolio

How many companies has Janus Henderson Investors invested in?▸

Janus Henderson Investors has invested in 229 companies tracked in our database. The portfolio spans multiple industries and funding stages, from seed-stage startups to late-stage companies.

What industries does Janus Henderson Investors invest in?▸

Janus Henderson Investors's top investment sectors include Biotechnology, Health Care, Therapeutics, Life Science, Medical. The firm invests across 24 different industry categories.

What is Janus Henderson Investors's largest investment?▸

Among tracked funding rounds, Definium Therapeutics received $805.0M in a Post-IPO Equity round. Janus Henderson Investors's total known invested capital is $34.7B.

What is the average investment size for Janus Henderson Investors?▸

Janus Henderson Investors's average investment size is $151.4M across its portfolio of 229 companies.

What are Janus Henderson Investors's most recent investments?▸

Recent Janus Henderson Investors portfolio additions include Star Therapeutics, Epicrispr Biotechnologies, Vaxcyte, Pyxis Oncology, AN2 Therapeutics. These companies were founded in 2020 or later.

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