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Main Sequence Ventures — Portfolio

Investor actively backing innovative startups and growth-stage companies across various industries and funding rounds.

97
Companies
$1.6B
Total invested
$18.5M
Avg. check
59
Industries
Artificial Intelligence (AI) 6Biotechnology 5Manufacturing 4Energy 3Renewable Energy 3Semiconductor 3+53 more
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Portfolio companies

Showing 1–24 of 97
Metacognition
September 2026

Metacognition is an AI company dedicated to building the next generation of intelligent AI agents and robotic software platforms.

Agentic AI · Adelaide$7.2M Pre-Seed
Kinoxis Therapeutics
September 2026

Kinoxis Therapeutics is a biotechnology company that develops a range of novel therapeutic compounds.

Biotechnology · Melbourne$4.8M Venture - Series Unknown
Amber Electric
September 2026

Amber Electric provides electricity plans based on wholesale energy prices with usage charges linked to market rates.

Artificial Intelligence (AI) · Melbourne$55.9M Series E
Endua
September 2025

Endua is developing the next generation of renewable energy multi-day storage solutions.

Energy Storage · Brisbane$20K Grant
Facet Amtech
August 2026

Facet Amtech develops and produces ammonia from water and air.

Chemical · Wickham$2.2M Seed
Millibeam
July 2024

Millibeam is an semiconductor firm that specializes in the creation of advanced radio-frequency and millimeter wave chipsets.

Electronics · Sydney$3.0M Venture - Series Unknown
Nourish Ingredients
July 2023

Nourish Ingredients is a food tech company that creates the same fat molecules as those found in animals.

Fitness · Canberra$3.9M Grant
Emesent
July 2026

Emesent is automating the collection and analysis of valuable data in underground environments.

Aerospace · Pullen Vale$10.4M Convertible Note
Number 8 bio
June 2026

Number 8 bio objective is to decarbonize agriculture while feeding the world's rising population.

Agriculture · Sydney$15K Grant
Indee Labs
June 2023

Indee Labs is unlocking gene-modified cell therapy for the masses with scalable hardware for gene delivery.

Biotechnology · San FranciscoNon-equity Assistance
JDoodle
June 2023

JDoodle is an AI powered online programming platform that offers online IDE, software compilers, APIs, embedded IDEs, and assessments.

Developer APIs · Canberra$2.2M Seed
Levur
May 2025

Levur is a Biotechnology Research oriented firm that manufactures cosmetic oil substitutes for their customers.

Biopharma · Sydney$780K Pre-Seed
Diraq
May 2026

Diraq develops quantum computers utilizing modified silicon transistors, making them suitable for utility-scale applications.

Computer · Sydney$38.0M Grant
Arkeus
May 2026

Arkeus develops AI-powered sensing and surveillance systems designed for autonomous platforms.

Artificial Intelligence (AI) · Port Melbourne$17.9M Series A
Skykraft
April 2024

Skykraft is an Australian space services firm that specializes in smallsat constellation design, production, and operation.

Service Industry · Australian Capital Territory$2.4M Grant
Baraja
April 2023

Baraja is a deep technology company that has reinvented LiDAR for self-driving vehicles.

3D Technology · SydneyCorporate Round
DeteQt
April 2026

Pioneers quantum magnetometry for navigation, mining, and medical imaging solutions

Information Technology · Sydney$3.5M Seed
ULUU
April 2026

ULUU is an ocean material that replaces plastic and actively benefits the world.

Advanced Materials · Perth$1.5M Grant
Maxwell Plus
March 2022

Maxwell Plus is an AI platform for data driven clinical diagnostics.

Artificial Intelligence (AI) · BrisbaneNon-equity Assistance
Regrow Ag
March 2025

Regrow is an agritech company that promotes regenerative agriculture to build a climate-resilient global food production system.

Agriculture · DurhamVenture - Series Unknown
Cauldron Ferm
March 2026

Cauldron Ferm is a bio-acceleration process that exponentially scales up any precision fermented prototype to commercial quantities.

Biotechnology · Orange$13.3M Series A
Advanced Navigation
March 2026

Advanced Navigation creates AI-powered navigation systems and robotics technologies for use in the air, land, sea, and space.

Artificial Intelligence (AI) · Sydney$111.9M Series C
MGA Thermal
March 2026

Making 24/7 renewables a reality through Thermal Energy Storage.

Energy · Newcastle$12.0M Series Unknown
Quasar Satellite Technologies
February 2024

Quasar Satellite Technologies provides ground station service for satellite operators and users.

Satellite Communication · SydneyNon-equity Assistance

Where Main Sequence Ventures invests

Artificial Intelligence (AI)6
Biotechnology5
Manufacturing4
Energy3
Renewable Energy3
Semiconductor3

About Main Sequence Ventures's portfolio

How many companies has Main Sequence Ventures invested in?▸

Main Sequence Ventures has invested in 97 companies tracked in our database. The portfolio spans multiple industries and funding stages, from seed-stage startups to late-stage companies.

What industries does Main Sequence Ventures invest in?▸

Main Sequence Ventures's top investment sectors include Artificial Intelligence (AI), Biotechnology, Manufacturing, Energy, Renewable Energy. The firm invests across 59 different industry categories.

What is Main Sequence Ventures's largest investment?▸

Among tracked funding rounds, Advanced Navigation received $111.9M in a Series C round. Main Sequence Ventures's total known invested capital is $1.6B.

What is the average investment size for Main Sequence Ventures?▸

Main Sequence Ventures's average investment size is $18.5M across its portfolio of 97 companies.

What are Main Sequence Ventures's most recent investments?▸

Recent Main Sequence Ventures portfolio additions include Metacognition, Kinoxis Therapeutics, Amber Electric, Endua, Facet Amtech. These companies were founded in 2020 or later.

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