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National Science Foundation Portfolio Companies

Investor actively backing innovative startups and growth-stage companies across various industries and funding rounds.

Last updated: July 2026

National Science Foundation Investment Overview

Portfolio Companies
1,670
Total Invested
$6.8B
Average Investment
$5.9M

National Science Foundation's Most Recent Investments (2020+)

Company NameFoundedFunding StageAmountCity
Optimeos Life Sciences2026Venture - Series UnknownUndisclosedPrinceton
Andluca2026SeedUndisclosedPrinceton
Syzygy Plasmonics2026Venture - Series UnknownUndisclosedHouston
Phoenix Tailings2026Debt Financing$30.2MWoburn
Swift Coat2026GrantUndisclosedPeoria
Celadyne Technologies2026Venture - Series Unknown$4.5MChicago
Anello Photonics2026Series BUndisclosedSanta Clara
Silvis Materials2026Grant$250KBoulder
Samay2026SeedUndisclosedMountain View
Centese2026Venture - Series Unknown$15.0MOmaha

Complete List of National Science Foundation Portfolio Companies (1,670)

Export
#CompanyStageAmountLocation
1Optimeos Life SciencesVenture - Series UnknownUndisclosedPrinceton, United States
2AndlucaSeedUndisclosedPrinceton, United States
3Syzygy PlasmonicsVenture - Series UnknownUndisclosedHouston, United States
4Phoenix TailingsDebt Financing$30.2MWoburn, United States
5Swift CoatGrantUndisclosedPeoria, United States
6Celadyne TechnologiesVenture - Series Unknown$4.5MChicago, United States
7Anello PhotonicsSeries BUndisclosedSanta Clara, United States
8Silvis MaterialsGrant$250KBoulder, United States
9SamaySeedUndisclosedMountain View, United States
10CenteseVenture - Series Unknown$15.0MOmaha, United States
BiotechnologyLife ScienceMedical

Optimeos Life Sciences is a biotechnology company that enables the use of biologics, peptides, and RNA to treat diseases.

Princeton, United States
June 2026
Venture - Series Unknown

Founder Contacts

19,000+ verified contacts

ElectronicsRenewable EnergySmart BuildingSolar

Andluca designs and develops advanced materials and systems for applications in fenestration and other applications.

Princeton, United States
June 2026
Seed

Founder Contacts

19,000+ verified contacts

ChemicalChemical Engineering

Syzygy Plasmonics is a developer of a photocatalytic reactor designed for fuel cell vehicles and small-scale industrial applications.

Houston, United States
June 2026
Venture - Series Unknown

Founder Contacts

19,000+ verified contacts

Advanced MaterialsCleanTechIndustrialManufacturingMiningSustainabilityWaste Management

Phoenix Tailings is a rare earth metals production company that transforms mining waste (tailings) into usable rare earth metals and alloys.

Woburn, United States
June 2026
$30.2M
Debt Financing

Founder Contacts

19,000+ verified contacts

Product ResearchSolar

Swift Coat is an Arizona-based research company that develops thin films

Peoria, United States
June 2026
Grant

Founder Contacts

19,000+ verified contacts

ChemicalEnergy StorageFuel CellIndustrial

Celadyne Technologies develops membranes for use in electrolyzers and fuel cells that require minimal heat and water management.

Chicago, United States
May 2026
$4.5M
Venture - Series Unknown

Founder Contacts

19,000+ verified contacts

AerospaceElectronicsNavigationSemiconductor

Anello Photonics is a technology company developing a silicon photonic optical gyroscope to navigate autonomous applications.

Santa Clara, United States
May 2026
Series B

Founder Contacts

19,000+ verified contacts

Building MaterialChemicalChemical EngineeringIndustrial Manufacturing

Sustainable, bio-degradable adhesives and binders

Boulder, United States
May 2026
$250K
Grant

Founder Contacts

19,000+ verified contacts

Artificial Intelligence (AI)Health DiagnosticsMachine LearningMedical DeviceWearables

AI patch platform for COPD diagnosis and management

Mountain View, United States
May 2026
Seed

Founder Contacts

19,000+ verified contacts

Health CareMedical Device

Centese develops cardiothoracic post-operative medical equipment for post-operative surgical care and patient monitoring.

Omaha, United States
May 2026
$15.0M
Venture - Series Unknown

Founder Contacts

19,000+ verified contacts

BiotechnologyChemicalIndustrialManufacturing

Zymochem provides a carbon-efficient bio-manufacturing platform that converts renewable feedstocks into bio-based materials.

San Leandro, United States
May 2026
Grant

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CareTherapeutics

Remedium Bio is a gene therapy company focused on the development of highly innovative treatments for a broad range of diseases.

Needham, United States
May 2026
Venture - Series Unknown

Founder Contacts

19,000+ verified contacts

Biotechnology

Auxilium Health is creating low-cost, smart biomaterials for difficult-to-heal wounds.

Akron, United States
May 2026
$1.5M
Seed

Founder Contacts

19,000+ verified contacts

Advanced MaterialsAugmented RealityOptical CommunicationQuantum ComputingSemiconductor

Phosio Corporation creates materials used to deposit metal oxides at low temperatures.

Corvallis, United States
May 2026
$1.1M
Seed

Founder Contacts

19,000+ verified contacts

BatteryElectric VehicleElectronicsManufacturingNanotechnology

Sila is a battery materials company that manufactures energy-density lithium-ion batteries for electric vehicles.

Alameda, United States
April 2026
Secondary Market

Founder Contacts

19,000+ verified contacts

BiotechnologyGeneticsHealth CareLife Science

Kytopen develops genome engineering platforms that enable cell therapy research and manufacturing.

Cambridge, United States
April 2026
Series B

Founder Contacts

19,000+ verified contacts

AgricultureBiotechnologyChemical

Provivi develops biopesticides for agriculture, commercial, household, and public health pest management.

Santa Monica, United States
April 2026
Debt Financing

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CareLife Science

Ancilia Biosciences offers bacterial therapeutics that address the microbiome's viral components.

New York, United States
April 2026
$4.2M
Venture - Series Unknown

Founder Contacts

19,000+ verified contacts

Health CareMedical DevicePersonal Health

Elidah's ELITONE is a medical device that allows women to be boss of their bladders, whether stress or urge incontinence.

Monroe, United States
April 2026
Venture - Series Unknown

Founder Contacts

19,000+ verified contacts

BiotechnologyHealth CareHealth DiagnosticsMedicalMedical Device

JuneBrain is an early start-up company that helps multiple sclerosis patients through the power of telemedicine.

Washington, United States
April 2026
$450K
Venture - Series Unknown

Founder Contacts

19,000+ verified contacts

BatteryElectric VehicleManufacturingNanotechnologyRenewable Energy

Coreshell Technologies is a nanotechnology company that is a developer of nanolayer coating technology for rechargeable batteries.

San Leandro, United States
April 2026
$24.0M
Series B

Founder Contacts

19,000+ verified contacts

Health CareMedicalMedical Device

Illuminant Surgical is building a new way of seeing inside the human body.

Los Angeles, United States
April 2026
Seed

Founder Contacts

19,000+ verified contacts

Cloud ComputingSimulationSoftware

JuliaHub is a single platform for modeling, simulation, and user built applications.

Cambridge, United States
April 2026
$13.0M
Series B

Founder Contacts

19,000+ verified contacts

CleanTechIndustrialIndustrial ManufacturingManufacturingPrecious MetalsRenewable Energy

Electra is a a clean iron company that uses a low-temperature, electrochemical-hydrometallurgical system to refine iron ore.

Boulder, United States
April 2026
$30.0M
Venture - Series Unknown

Founder Contacts

19,000+ verified contacts

Electronic Health Record (EHR)Health CareSoftwareWellness

Koda Health offers digital healthcare solutions and services that focuses on advance care planning and kidney care.

Houston, United States
April 2026
$7.0M
Series A

Founder Contacts

19,000+ verified contacts

Showing 1-25 of 1,670 portfolio companies

Frequently Asked Questions About National Science Foundation

How many companies has National Science Foundation invested in?

National Science Foundation has invested in 1,670 companies tracked in our database. The portfolio spans multiple industries and funding stages, from seed-stage startups to late-stage companies.

What industries does National Science Foundation invest in?

National Science Foundation's top investment sectors include Biotechnology, Health Care, Chemical, Manufacturing, Medical Device. The firm invests across 46 different industry categories.

What is National Science Foundation's largest investment?

Among tracked funding rounds, Phoenix Tailings received $30.2M in a Debt Financing round. National Science Foundation's total known invested capital is $6.8B.

What is the average investment size for National Science Foundation?

National Science Foundation's average investment size is $5.9M across its portfolio of 1,670 companies.

What are National Science Foundation's most recent investments?

Recent National Science Foundation portfolio additions include Optimeos Life Sciences, Andluca, Syzygy Plasmonics, Phoenix Tailings, Swift Coat. These companies were founded in 2020 or later.

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