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NFX — Portfolio

Investor actively backing innovative startups and growth-stage companies across various industries and funding rounds.

214
Companies
$3.5B
Total invested
$16.7M
Avg. check
52
Industries
Artificial Intelligence (AI) 8Biotechnology 6Health Care 5Software 4Information Technology 4Internet 4+46 more
Founder contacts

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Portfolio companies

Showing 1–24 of 214
F2 AI
September 2026

F2 AI offers an AI platform that support decision-making workflows in private markets.

Artificial Intelligence (AI) · New York$5.0M Private Equity
Talus Bio
September 2026

Talus Bio is a drug discovery biotech company that develops drugs targeting undruggable transcription factors using AI.

Artificial Intelligence (AI) · Seattle$11.2M Seed
Latitude
September 2026

Latitude is working on a global payments system that links stablecoin-based settlement with local currency payout systems.

Financial Services · Spring$35.0M Series A
TwoStep Therapeutics
September 2026

TwoStep Therapeutics is developing novel tumor-targeting therapeutics for solid tumors.

Biotechnology · Palo Alto$62.5M Series A
Velocity
July 2026

Velocity builds ad infra to monetize AI chat using real-time intent.

Advertising · New YorkCorporate Round
Aligned
July 2026

Aligned is an AI-powered workspace designed for B2B sales teams, facilitating deals in a collaborative environment.

Artificial Intelligence (AI) · Wilmington$60.0M Series B
Pumpkinseed Technologies
May 2026

Pumpkinseed allows for high-speed readings of biological bits.

Biotechnology · Palo Alto$20.0M Series A
Blitzy
May 2026

Blitzy is a Generative AI software platform that aims to automate custom software development.

Artificial Intelligence (AI) · Boston$200.0M Series A
CopilotKit
May 2026

CopilotKit is the full-stack framework for building user interactive agents and copilots. The company behind the AG-UI Protocol.

Developer Platform · Seattle$20.5M Series A
TradeForm
April 2026

The AI operating system for supply chain teams.

Manufacturing · San Francisco$2.0M Pre-Seed
Gizmo
April 2026

Gizmo provides an AI learning platform that uses adaptive flashcards and spaced repetition to improve study and retention.

Artificial Intelligence (AI) · London$22.0M Series A
OpenFX
March 2026

OpenFX provides a real-time cross-border payment infrastructure that provides liquidity across different trading pairs.

Embedded Software · New City$94.0M Series A
Centivax
March 2026

Centivax is a biotechnology company that develops vaccines and therapeutic antibodies targeting infectious diseases and venomous threats.

Biotechnology · South San Francisco$37.0M Series Unknown
ScaleOps
March 2026

ScaleOps automates Kubernetes resource optimization, helping organizations reduce cloud costs and enhance operational efficiency.

AI Infrastructure · New York$130.0M Series C
ImmuneBridge
March 2026

ImmuneBridge is developing allogeneic immunotherapies for cancer.

Biotechnology · San Francisco$7.7M Seed
Rexi
March 2026

Rexi is an AI-native financial reconciliation tool designed for banks, payment businesses, and contemporary fintechs.

New Castle$1.2M Pre-Seed
Guild.ai
March 2026

AI, Software Development

Artificial Intelligence (AI) · San Francisco$30.0M Series A
Levl
February 2026

Levl GmbH is a Swiss fintech company focused on cross-border payments and global payment infrastructure.

Financial Services · Zug$7.0M Seed
Known
December 2025

Known is a SaaS company that offers an online dating app.

Apps · San Francisco$9.7M Seed
On Me
December 2025

On Me is a software company that creates a platform for sending digital gift cards for hobbies and interests.

Apps · San Francisco$6.0M Seed
Palo AI
November 2025

Palo AI is a digital platform for social media creators that provides personal AI assistance to amplify creativity.

Artificial Intelligence (AI) · Palo Alto$3.8M Seed
Peek
November 2025

Peek is a travel-tech platform designed for booking tours and provides software for tour and activity operators to manage their businesses.

Internet · San Francisco$70.0M Series D
Ginia
October 2025

Ginia is an edtech company that connects companies, educational institutions and students to enhance employability.

Artificial Intelligence (AI) · Mexico City$1.7M Pre-Seed
Cyclana Bio
October 2025

Cyclana Bio is to enhancing women's quality of life by offering a fresh approach to therapeutic research.

Biotechnology · Cambridge$6.7M Pre-Seed

Where NFX invests

Artificial Intelligence (AI)8
Biotechnology6
Health Care5
Software4
Information Technology4
Internet4

About NFX's portfolio

How many companies has NFX invested in?▸

NFX has invested in 214 companies tracked in our database. The portfolio spans multiple industries and funding stages, from seed-stage startups to late-stage companies.

What industries does NFX invest in?▸

NFX's top investment sectors include Artificial Intelligence (AI), Biotechnology, Health Care, Software, Information Technology. The firm invests across 52 different industry categories.

What is NFX's largest investment?▸

Among tracked funding rounds, Blitzy received $200.0M in a Series A round. NFX's total known invested capital is $3.5B.

What is the average investment size for NFX?▸

NFX's average investment size is $16.7M across its portfolio of 214 companies.

What are NFX's most recent investments?▸

Recent NFX portfolio additions include F2 AI, Talus Bio, Latitude, TwoStep Therapeutics, Velocity. These companies were founded in 2020 or later.

Reach the founders behind these 214 companies
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