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Polaris Partners — Portfolio

Investor actively backing innovative startups and growth-stage companies across various industries and funding rounds.

186
Companies
$10.0B
Total invested
$53.8M
Avg. check
33
Industries
Biotechnology 15Health Care 13Therapeutics 7Medical 5Artificial Intelligence (AI) 4Biopharma 3+27 more
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Portfolio companies

Showing 1–24 of 186
Allstacks
October 2026

Allstacks develops a software engineering intelligence platform to predict forecasting and risk management.

Business Intelligence · Raleigh$4.0M Venture - Series Unknown
UpDoc
September 2026

UpDoc is a technology-enabled services company that offers the first-ever proprietary conversational AI platform for autonomous.

Artificial Intelligence (AI) · Palo Alto$9.2M Grant
Faro AI
August 2026

Faro Health develops software to assists clinical development processes, including workflow automation and clinical trial design.

Artificial Intelligence (AI) · La Jolla$37.3M Series B
Engine Biosciences
June 2026

Engine Biosciences is a biotech company that applies machine learning to genomics for drug discovery.

Artificial Intelligence (AI) · SingaporeVenture - Series Unknown
Leyden Labs
June 2026

Leyden Labs provides a platform that targets commonalities of viral families to protect humanity from known and future viruses.

Biotechnology · Amsterdam$45.4M Undisclosed
Triveni Bio
June 2026

Triveni Bio is a biotechnology company that develops antibody-based therapeutics for immunological and inflammatory diseases.

Biotechnology · Watertown$65.0M Series C
Tavo Biotherapeutics
June 2026

Tavo Biotherapeutics is a biotech company that develops injection therapies for eye diseases.

Biotechnology · Dorchester$17.0M Series A
Whisker Labs
May 2026

Whisker Labs develops cutting-edge sensor technology to protect homes and communities from electrical fires and bad utility power.

Artificial Intelligence (AI) · Germantown$6.6M Series D
Crossbow Therapeutics
March 2026

Crossbow Therapeutics is a biotech company that develops targeted therapies to address cancer antigens.

Biotechnology · Cambridge$77.0M Series B
Tropic Biosciences
March 2026

Tropic Biosciences is a pioneering leader in the development of novel high-performing commercial tropical crop varieties and traits.

Agriculture · London$105.0M Series C
BarkBox
January 2026

Barkbox is a monthly subscription service platform that provides dog products.

E-Commerce · New York$35.0M Post-IPO Debt
Mesodyne
January 2026

Mesodyne manufactures the LightCell: a high energy density, silent, compact power generator converting any fuel to electricity via light.

Energy · SomervilleGrant
Primmune Therapeutics
January 2026

Primmune Therapeutics is a Biotechnology company.

Biotechnology · San Diego$8.6M Series B
Muna Therapeutics
January 2026

Muna Therapeutics discovers and develops therapies that slow or stop neurodegenerative diseases such as alzheimer’s and parkinson's.

Biopharma · Copenhagen$1.0M Grant
EpiBiologics
January 2026

EpiBiologics develops antibody-based targeted therapies against membrane and extracellular proteins.

Biotechnology · San Mateo$107.0M Series B
Nomad Health
December 2025

Nomad Health is an online staffing marketplace that connects clinicians to healthcare jobs.

Health Care · New York$33.8M Venture - Series Unknown
Invivyd
November 2025

Invivyd develops antibodies to transcend the limitations of the human immune system and fight against viral infections.

Biotechnology · Waltham$125.0M Post-IPO Equity
Proof
November 2025

Proof is an identity-assured transaction management platform that verifies identities and secures digital transactions.

Legal · Boston$15.7M Venture - Series Unknown
Sovato Health
November 2025

Sovato Health provides surgical access through remote robotic surgeon options.

Health Care · Santa Barbara$41.0M Series B
Indomo
October 2025

Indomo is a clinical-stage firm that aims to improve access to quality healthcare through novel device-enabled treatments.

Biotechnology · San Francisco$25.0M Seed
Zag Bio
October 2025

Zag Bio is a biotechnology company that designs thymus-targeting bifunctional antibody medicines to treat and prevent autoimmune diseases.

Biopharma · Cambridge$80.0M Series A
Cirrus Therapeutics
August 2025

Cirrus Therapeutics is a Biotechnology Research firm diganosing and treating eye diseases affecting ocular immune system.

Biotechnology · Cambridge$11.0M Seed
Compass Therapeutics
August 2025

Compass Therapeutics is a biopharmaceutical company that focuses on drugging the immune system to treat human diseases.

Biopharma · Boston$120.0M Post-IPO Equity
Auron Therapeutics
July 2025

Auron aims to cure cancer therapeutics from cell killing to transformation of malignant cells into more normal functioning cells.

Biotechnology · NewtonVenture - Series Unknown

Where Polaris Partners invests

Biotechnology15
Health Care13
Therapeutics7
Medical5
Artificial Intelligence (AI)4
Biopharma3

About Polaris Partners's portfolio

How many companies has Polaris Partners invested in?▸

Polaris Partners has invested in 186 companies tracked in our database. The portfolio spans multiple industries and funding stages, from seed-stage startups to late-stage companies.

What industries does Polaris Partners invest in?▸

Polaris Partners's top investment sectors include Biotechnology, Health Care, Therapeutics, Medical, Artificial Intelligence (AI). The firm invests across 33 different industry categories.

What is Polaris Partners's largest investment?▸

Among tracked funding rounds, Invivyd received $125.0M in a Post-IPO Equity round. Polaris Partners's total known invested capital is $10.0B.

What is the average investment size for Polaris Partners?▸

Polaris Partners's average investment size is $53.8M across its portfolio of 186 companies.

What are Polaris Partners's most recent investments?▸

Recent Polaris Partners portfolio additions include Allstacks, UpDoc, Faro AI, Engine Biosciences, Leyden Labs. These companies were founded in 2020 or later.

Reach the founders behind these 186 companies
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