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RA Capital Management — Portfolio

Investor actively backing innovative startups and growth-stage companies across various industries and funding rounds.

467
Companies
$56.7B
Total invested
$123.5M
Avg. check
23
Industries
Biotechnology 20Health Care 15Therapeutics 11Medical 10Pharmaceutical 9Life Science 8+17 more
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Portfolio companies

Showing 1–24 of 467
Aclaris Therapeutics
October 2026

Aclaris Therapeutics is a specialty pharmaceutical company engaged in developing dermatologic therapies.

Biotechnology · Wayne$50.0M Post-IPO Equity
Star Therapeutics
October 2026

Star Therapeutics mission is to develop therapies for as many diseases as possible for millions of patients.

Health Care · South San Francisco$200.0M Venture - Series Unknown
Optivolt
October 2026

Millions of homes just became eligible for solar power.

Energy · San Francisco$32.0M Series A
Adela
October 2026

Adela creates develops technologies centered around detecting high-risk conditions like cancer through routine blood tests.

Biotechnology · Foster City$12.0M Convertible Note
Estuary Biotherapeutics
October 2026

Estuary Biotherapeutics is a biotechnology company developing genetic medicines for serious kidney diseases.

Biotechnology · San Francisco$93.0M Series A
MMI
October 2026

MMI is a medical technology company that develops robotic systems for microsurgery and supermicrosurgery.

Health Care · Jacksonville$125.0M Series D
Vaxcyte
October 2026

Vaxcyte focuses on developing vaccines designed to prevent or treat some of the most common and deadly infectious diseases worldwide.

Biopharma · San Carlos$575.0M Post-IPO Debt
Pyxis Oncology
September 2026

Pyxis Oncology is a biotechnology firm that develops antibody therapeutics intended to promote the body's immune response to cancer.

Biotechnology · Boston$110.0M Post-IPO Equity
AN2 Therapeutics
September 2026

AN2 Therapeutics develops small-molecule medicines from boron chemistry for infectious diseases, hematologic disorders, and oncology.

Biotechnology · Menlo Park$40.0M Grant
Navigator Medicines
September 2026

Navigator Medicines operate as a biotech company.

Biotechnology · Scotch Plains$10.0M Venture - Series Unknown
Circle Pharma
September 2026

Circle Pharma is a biotechnology company creating bioavailable macrocyclic peptide therapeutics that target protein-protein interactions.

Biotechnology · San Francisco$92.5M Series E
Planted
September 2026

Planted is a solar deployment technology company that uses AI powered robots and software to plan and deploy solar projects.

Artificial Intelligence (AI) · Oakland$31.8M Venture - Series Unknown
Tyra Biosciences
September 2026

Tyra Biosciences is a biotechnology company targeting new pathways of acquired resistance in oncology with purpose-built drugs.

Biotechnology · Carlsbad$400.0M Post-IPO Equity
Solstice Oncology
September 2026

Solstice Oncology develops immuno-oncology therapies focused on treating and preventing cancer through targeted approaches.

Biopharma · Boston$225.0M Series A
Tectora Therapeutics
September 2026

Tectora Therapeutics is a biotechnology company developing oral medicines for immune-mediated diseases.

Biotechnology · New York$55.0M Series A
Helus Pharma
September 2026

Helus Pharma is a biopharmaceutical company that develops psychedelic therapeutics for mental health conditions.

Biotechnology · Toronto$50.0M Post-IPO Equity
Korsana Biosciences
September 2026

Korsana Biosciences develops THETA-enabled antibody therapies for neurodegenerative diseases including Alzheimer’s.

Biopharma · Waltham$380.0M Post-IPO Equity
Superluminal Medicines
September 2026

Superluminal Medicines develops small-molecule therapeutics using AI, biology, and chemistry.

Artificial Intelligence (AI) · Boston$65.5M Series B
Typewriter Therapeutics
September 2026

Typewriter Therapeutics develops mRNA-based gene therapies using a gene writing platform for site-specific insertion of therapeutic genes.

Biopharma · Cambridge$56.3M Series A
AusperBio
August 2026

AusperBio is a biotechnology company focused on developing oligonucleotide therapeutics and targeted delivery technologies.

Biopharma · San Mateo$120.0M Series C
Expedition Therapeutics
August 2026

Expedition Therapeutics develops treatments for COPD and other inflammatory respiratory diseases.

Biotechnology · San Francisco$115.0M Series B
SAB Biotherapeutics
March 2026

SAB Biotherapeutics is a clinical-stage biopharmaceutical development company.

Biotechnology · Sioux Falls$85.0M Post Ipo Equity
Equillium
March 2026

Equillium is a biotechnology company that develops products for autoimmune and inflammatory disorders with an unmet medical need.

Biopharma · La Jolla$35.0M Post Ipo Equity
Solid Biosciences
March 2026

Solid Biosciences is a life science company that conducts research for the treatment of Duchenne muscular dystrophy.

Biotechnology · Charlestown$240.0M Post Ipo Equity

Where RA Capital Management invests

Biotechnology20
Health Care15
Therapeutics11
Medical10
Pharmaceutical9
Life Science8

About RA Capital Management's portfolio

How many companies has RA Capital Management invested in?▸

RA Capital Management has invested in 467 companies tracked in our database. The portfolio spans multiple industries and funding stages, from seed-stage startups to late-stage companies.

What industries does RA Capital Management invest in?▸

RA Capital Management's top investment sectors include Biotechnology, Health Care, Therapeutics, Medical, Pharmaceutical. The firm invests across 23 different industry categories.

What is RA Capital Management's largest investment?▸

Among tracked funding rounds, Vaxcyte received $575.0M in a Post-IPO Debt round. RA Capital Management's total known invested capital is $56.7B.

What is the average investment size for RA Capital Management?▸

RA Capital Management's average investment size is $123.5M across its portfolio of 467 companies.

What are RA Capital Management's most recent investments?▸

Recent RA Capital Management portfolio additions include Aclaris Therapeutics, Star Therapeutics, Optivolt, Adela, Estuary Biotherapeutics. These companies were founded in 2020 or later.

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