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RA Capital Management — Portfolio, Page 6

Investor actively backing innovative startups and growth-stage companies across various industries and funding rounds.

467
Companies
$56.7B
Total invested
$123.5M
Avg. check
20
Industries
Biotechnology 19Therapeutics 13Health Care 11Pharmaceutical 9Medical 7Biopharma 7+14 more
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Portfolio companies

Showing 121–144 of 467
Rani Therapeutics
October 2025

Rani is a clinical-stage biotherapeutics company that enables the development of orally administered biologics to improve patient outcomes.

Biotechnology · San Jose$60.3M Post-IPO Equity
Adcytherix
October 2025

Adcytherix is a biopharmaceutical firm that specializes in the development of new antibody drug conjugates (ADC).

Biotechnology · Marseille$122.4M Series A
C4 Therapeutics
October 2025

C4 Therapeutics develops novel early stage therapies that eliminate disease-causing proteins.

Biotechnology · Cambridge$125.0M Post-IPO Equity
LEXEO Therapeutics
October 2025

LEXEO Therapeutics utilizes gene therapy to treat genetically defined cardiovascular and central nervous system diseases.

Biotechnology · New York$154.0M Post-IPO Equity
Adagio Medical
October 2025

Adagio Medical is engaged in the research and development of treatments for cardiovascular diseases.

Health Care · Laguna Hills$19.0M Post-IPO Equity
Indapta Therapeutics
October 2025

Indapta Therapeutics is a privately held biotechnology company.

Biopharma · San Francisco$50.8M Venture - Series Unknown
TORL BioTherapeutics
October 2025

TORL BioTherapeutics is a clinical-stage biopharmaceutical business.

Biopharma · Culver City$96.0M Series C
Affinia Therapeutics
October 2025

Affinia Therapeutics is a biotechnology company developing transformative AAV gene therapies for people with rare and prevalent diseases.

Biotechnology · Waltham$40.0M Series C
Cidara Therapeutics
October 2025

Cidara Therapeutics develops targeted immunotherapies aimed at improving treatment outcomes for patients with serious diseases.

Biotechnology · San Diego$339.0M Grant
Ansa Biotechnologies
October 2025

Ansa Biotechnologies develops a novel DNA synthesis technology based on enzymes.

Biotechnology · Emeryville$45.2M Series B
IO Biotech
September 2025

IO Biotech is a clinical-stage biotech company developing disruptive immune therapies for the treatment of cancer.

Biotechnology · Copenhagen$6.6M Post-IPO Equity
ARS Pharmaceuticals
September 2025

ARS Pharmaceuticals is a stealth pharmaceutical company that specializes in developing anti allergy drugs.

Biopharma · San Diego$100.0M Post-IPO Debt
Sparrow Pharmaceuticals
September 2025

Sparrow Pharmaceuticals is a clinical-stage biopharmaceutical company developing treatments for disorders of corticosteroid excess.

Biopharma · Portland$95.0M Series B
KalVista Pharmaceuticals
September 2025

KalVista Pharmaceuticals focuses on developing oral medicines, particularly for managing hereditary angioedema.

Biopharma · Cambridge$125.0M Post-IPO Debt
Pepgen
September 2025

PepGen is empowering nucleic acid therapeutics to go the distance.

Biotechnology · Oxford$115.0M Post-IPO Equity
Monopar
September 2025

Monopar Therapeutics is an emerging biopharmaceutical company focused on developing orphan oncology compounds.

Biopharma · Wilmette$135.0M Post-IPO Equity
Metalex Commodities
September 2025

Metalex Commodities is a commodity trading company that specializes in the export of metal ores and concentrates.

Precious Metals · Houston$1.4M Grant
Avidity Biosciences
September 2025

Synapse Energy Economics is a consulting firm providing economic and policy analysis for the electric power sector.

Biotechnology · San Diego$690.0M Post-IPO Equity
Delix Therapeutics
September 2025

Delix Therapeutics focuses on harnessing the power of psychoplastogens novel neuroplasticity-promoting therapeutic.

Biotechnology · Boston$25.0M Series B
Reframe Systems
August 2025

Robotic microfactories for building net-zero homes 2x faster, 2x cheaper with 10x lower carbon

Construction · Andover$20.0M Series A
Plexium
August 2025

Plexium develops a targeted protein degradation platform to find new therapies for cancer and other diseases.

Biotechnology · San Diego$60.1M Series C
Arvinas
August 2025

Arvinas advances therapies degrading disease-causing proteins for life-threatening diseases, from discovery to commercialization.

Biotechnology · New HavenPost-IPO Equity
Gameto
August 2025

Gameto is a biotechnology company developing therapeutics of the female reproductive system using cell engineering.

Biopharma · New York$44.0M Series C
Iterum Therapeutics
August 2025

Iterum Therapeutics is a clinical-stage pharmaceutical company that develops significantly differentiated anti-infectives.

Medical · Dublin$2.2M Post-IPO Equity

Where RA Capital Management invests

Biotechnology19
Therapeutics13
Health Care11
Pharmaceutical9
Medical7
Biopharma7

About RA Capital Management's portfolio

How many companies has RA Capital Management invested in?▸

RA Capital Management has invested in 467 companies tracked in our database. The portfolio spans multiple industries and funding stages, from seed-stage startups to late-stage companies.

What industries does RA Capital Management invest in?▸

RA Capital Management's top investment sectors include Biotechnology, Therapeutics, Health Care, Pharmaceutical, Medical. The firm invests across 20 different industry categories.

What is RA Capital Management's largest investment?▸

Among tracked funding rounds, Avidity Biosciences received $690.0M in a Post-IPO Equity round. RA Capital Management's total known invested capital is $56.7B.

What is the average investment size for RA Capital Management?▸

RA Capital Management's average investment size is $123.5M across its portfolio of 467 companies.

What are RA Capital Management's most recent investments?▸

Recent RA Capital Management portfolio additions include Rani Therapeutics, Adcytherix, C4 Therapeutics, LEXEO Therapeutics, Adagio Medical. These companies were founded in 2020 or later.

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