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RTW Investments — Portfolio

Investor actively backing innovative startups and growth-stage companies across various industries and funding rounds.

107
Companies
$11.5B
Total invested
$139.0M
Avg. check
15
Industries
Biotechnology 21Health Care 13Biopharma 7Medical 7Therapeutics 5Pharmaceutical 4+9 more
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Portfolio companies

Showing 124 of 107
Renovacor
September 2021

Renovacor is a biopharmaceutical company that focuses on developing transformative gene therapy‑based treatments for cardiovascular disease.

Biotechnology · Philadelphia$30.0M Post-IPO Equity
ACELYRIN
September 2022

ACELYRIN is a biopharma company that identifies, acquires, and accelerates the development and commercialization of life-changing therapies.

Biopharma · Los Angeles$300.0M Series C
Neurogastrx
August 2021

A private biopharmaceutical company .

Biotechnology · Woburn$60.0M Series B
Frequency Therapeutics
August 2022

Frequency Therapeutics develops small molecule drugs that activate progenitor cells within the body to restore healthy tissue.

Biotechnology · LexingtonPost-IPO Equity
Visus Therapeutics
August 2021

Visus Therapeutics is a clinical-stage company developing innovative medicines.

Biotechnology · Seattle$20.0M Debt Financing
LENZ Therapeutics
July 2024

LENZ Therapeutics operates as an organization engaged in the late-stage clinical development of pharmaceuticals for the eyes.

Health Care · Del Mar$30.0M Post-IPO Equity
INBRACE
July 2022

Swift Health Systems is a stealth stage start-up medical device company, developing INBRACE.

Consumer · Irvine$45.0M Debt Financing
Pyxis Oncology
June 2026

Pyxis Oncology is a biotechnology firm that develops antibody therapeutics intended to promote the body's immune response to cancer.

Biotechnology · Boston$50.0M Post-IPO Equity
MoonLake Immunotherapeutics
June 2026

MoonLake Immunotherapeutics is a clinical-stage biopharmaceuticals company.

Biotechnology · Zug$200.0M Post-IPO Equity
Orchestra BioMed
May 2026

Orchestra BioMed is a biomedical innovation company that provides high-impact solutions for large unmet needs in procedure-based medicine.

Biotechnology · New Hope$35.0M Post-IPO Debt
Ocugen
May 2026

Ocugen is a biotechnology company that develops novel gene and cell therapies to improve health and patient outcomes.

Biopharma · Malvern$115.0M Post-IPO Debt
Whitehawk Therapeutics
May 2026

Whitehawk Therapeutics, a clinical-stage oncology therapeutics firm, applies cutting-edge technologies to well-established tumor biology.

Biopharma · Pacific Palisades$87.5M Post-IPO Equity
ITeos Therapeutics
May 2024

ITeos Therapeutics is a biotechnology company that specializes in tumor immunology, cancer immunotherapy, and drug discovery.

Biotechnology · Cambridge$120.0M Post-IPO Equity
GH Research
April 2026

GH Research is a biopharmaceutical company developing novel therapies for the management of mental illness.

Biopharma · Dublin$117.5M Post-IPO Equity
Oruka Therapeutics
April 2026

Oruka Therapeutics is advancing innovative biologics to redefine patient care standards in chronic skin diseases.

Biotechnology · Waltham$700.4M Post-IPO Equity
Alcyone Therapeutics
April 2025

Alcyone Therapeutics is Pioneering Next-Generation Precision CNS Genetic Therapies to unlock new possibilities

Biotechnology · LowellCorporate Round
Cullinan Therapeutics
April 2024

Cullinan Therapeutics is a developer of an externally sourced cancer therapeutics used to end a drug program quickly.

Biopharma · Cambridge$280.0M Post-IPO Equity
Spyre Therapeutics
April 2026

Spyre Therapeutics is a biotechnology business that is developing a strong pipeline of antibody therapies.

Biotechnology · Sunrise$403.0M Post-IPO Equity
ImageneBio
April 2026

ImageneBio is dedicated to developing therapeutics for patients with immunological, autoimmune and inflammatory diseases

Biopharma · San Diego$30.0M Post-IPO Equity
AIRNA
April 2025

AIRNA develops RNA editing technologies to create medicines for various diseases.

Biotechnology · Cambridge$155.0M Series B
Prolium
March 2026

Prolium is a biotechnology company, which specializes in providing breakthrough therapies to the patients with autoimmune diseases.

Biotechnology · New York$50.0M Series A
Amani Therapeutics
March 2026

Amani uses cutting-edge research to break down barriers and provide people with severe mental illness with efficient treatments.

New York$25.0M Series A
SAB Biotherapeutics
March 2026

SAB Biotherapeutics is a clinical-stage biopharmaceutical development company.

Biotechnology · Sioux Falls$85.0M Post-IPO Equity
Tarsus Pharmaceuticals
March 2025

Tarsus Pharmaceuticals is a clinical-stage biopharmaceutical company that develops treatments for diseases with high unmet need.

Biopharma · Irvine$125.0M Post-IPO Equity

Where RTW Investments invests

Biotechnology21
Health Care13
Biopharma7
Medical7
Therapeutics5
Pharmaceutical4

About RTW Investments's portfolio

How many companies has RTW Investments invested in?

RTW Investments has invested in 107 companies tracked in our database. The portfolio spans multiple industries and funding stages, from seed-stage startups to late-stage companies.

What industries does RTW Investments invest in?

RTW Investments's top investment sectors include Biotechnology, Health Care, Biopharma, Medical, Therapeutics. The firm invests across 15 different industry categories.

What is RTW Investments's largest investment?

Among tracked funding rounds, Oruka Therapeutics received $700.4M in a Post-IPO Equity round. RTW Investments's total known invested capital is $11.5B.

What is the average investment size for RTW Investments?

RTW Investments's average investment size is $139.0M across its portfolio of 107 companies.

What are RTW Investments's most recent investments?

Recent RTW Investments portfolio additions include Renovacor, ACELYRIN, Neurogastrx, Frequency Therapeutics, Visus Therapeutics. These companies were founded in 2020 or later.

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