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Sam Altman — Portfolio

Investor actively backing innovative startups and growth-stage companies across various industries and funding rounds.

47
Companies
$1.1B
Total invested
$24.3M
Avg. check
61
Industries
Biotechnology 8Software 8Artificial Intelligence (AI) 6Therapeutics 4Information Technology 4Life Science 3+55 more
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Portfolio companies

Showing 1–24 of 47
Longshot Space Technologies
June 2026

Longshot Space develops hypersonic launch technologies to reduce space launch costs.

Aerospace · Emeryville$5.0M Venture - Series Unknown
Retro Biosciences
May 2026

Retro Biosciences focuses on cellular reprogramming, autophagy, and plasma-inspired therapeutics.

Biopharma · Redwood CityVenture - Series Unknown
Red Queen Bio
November 2025

Red Queen Bio works with frontier labs to map AI-enabled biothreats and pre-build medical countermeasures against them.

Artificial Intelligence (AI) · Boston$15.0M Seed
Arcadia Medicine
October 2025

Arcadia Medicine is a biotechnology company that creates psychedelic medicine to treat mental health issues.

Biotechnology · San Francisco$9.3M Seed
teachme.to
September 2025

Teachme.to is a community of learners discovering lessons for everything.

EdTech · San Diego$3.0M Seed
Coco
June 2025

A last-mile delivery service that deploys human-operated sidewalk robots to transport goods from merchants to their customers

E-Commerce · Santa Monica$80.0M Series B
Ashvattha Therapeutics
January 2025

Ashvattha Therapeutics is a clinical-stage biopharmaceutical company that develops precision nanomedicines for ophthalmology diseases.

Biotechnology · Redwood City$50.0M Series B
NOYACK
December 2024

NOYACK is an agentic AI company that helps users with wealth management and offers personalized financial guidance.

Agentic AI · New York$3.0M Seed
1910 Genetics
October 2024

1910 Genetics is a biotechnology company integrating AI, computation, and biological automation to improve drug development.

Artificial Intelligence (AI) · BostonVenture - Series Unknown
Terraformation
October 2024

Terraformation wants to solve climate change.

Agriculture · Kamuela$4.2M Grant
GALY
September 2024

GALY produces agriculture from cells in a facility, not plants in the field

Agriculture · San Francisco$33.0M Series B
Kami
August 2024

Kami is a digital learning platform that empowers everyone to #lovelearning.

Apps · AucklandPrivate Equity
ValueBase
June 2024

ValueBase is a software provider that focuses on offering cutting-edge options for real estate assessment.

Information Technology · Durham$6.3M Seed
APEX
May 2024

APEX is a AI security company that provides organizations to get visibility of GenAI activity.

Artificial Intelligence (AI) · Tel Aviv$7.0M Seed
Minicircle
April 2024

Minicircle develops a human genetic enhancement platform to facilitate life extension capabilities.

Biotechnology · Los Angeles$459K Venture - Series Unknown
Software Applications Incorporated
November 2023

Rethinking the personal computing experience

Artificial Intelligence (AI) · San Francisco$6.5M Seed
Mentra
September 2023

A neurodiversity-focused recruiting platform

Internet · Charlotte$3.5M Seed
Uncommon
June 2023

Uncommon is about providing with that juicy, tender, and delicious meat they love but without harming their health, planet, and animals.

Biotechnology · Cambridge$30.0M Series A
Arkham Intelligence
April 2023

Arkham Intelligence provides intelligence on cryptocurrency networks and the entities behind them.

Artificial Intelligence (AI) · New York$12.0M Series A
Queer Spaces
January 2023

Queer Spaces develops a group chat platform for queer communities and an app for the LGBTQ+ spectrum.

Developer Platform · Los AngelesSeed
Rewind AI
January 2023

Rewind AI provides a Mac app that captures and searches through everything seen, said, or heard on a device.

Artificial Intelligence (AI) · Denver$17.9M Series A
TipTop
May 2022

TipTop operates an electronics resale platform that provides trade-in valuation and credit for used devices toward new purchases.

Consumer Electronics · Anaheim$23.0M Series A
Locket Labs
April 2022

Locket Labs is an app that allows users to share photos directly to the home screens of their family and friends.

Information Technology · Venice$10.0M Seed
Context
April 2022

Context is a Web3 business that allows users to “track” the transactions of any crypto wallet.

Apps · San Francisco$19.5M Seed

Where Sam Altman invests

Biotechnology8
Software8
Artificial Intelligence (AI)6
Therapeutics4
Information Technology4
Life Science3

About Sam Altman's portfolio

How many companies has Sam Altman invested in?▸

Sam Altman has invested in 47 companies tracked in our database. The portfolio spans multiple industries and funding stages, from seed-stage startups to late-stage companies.

What industries does Sam Altman invest in?▸

Sam Altman's top investment sectors include Biotechnology, Software, Artificial Intelligence (AI), Therapeutics, Information Technology. The firm invests across 61 different industry categories.

What is Sam Altman's largest investment?▸

Among tracked funding rounds, Coco received $80.0M in a Series B round. Sam Altman's total known invested capital is $1.1B.

What is the average investment size for Sam Altman?▸

Sam Altman's average investment size is $24.3M across its portfolio of 47 companies.

What are Sam Altman's most recent investments?▸

Recent Sam Altman portfolio additions include Longshot Space Technologies, Retro Biosciences, Red Queen Bio, Arcadia Medicine, teachme.to. These companies were founded in 2020 or later.

Reach the founders behind these 47 companies
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