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SignalFire — Portfolio

Investor actively backing innovative startups and growth-stage companies across various industries and funding rounds.

211
Companies
$4.5B
Total invested
$21.2M
Avg. check
50
Industries
Artificial Intelligence (AI) 14Software 9Information Technology 7Financial Services 5SaaS 4Health Care 3+44 more
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Portfolio companies

Showing 1–24 of 211
Preference Model
October 2026

Preference Model develops reinforcement learning environments for training AI systems to perform machine learning research.

Artificial Intelligence (AI) · San Francisco$16.0M Seed
Outmarket AI
September 2026

Outmarket provides an AI platform that helps insurance brokerages by automating critical workflows and delivering actionable insights.

Artificial Intelligence (AI) · San Francisco$34.5M Series B
Flagler Health
August 2026

Flagler Health assists physicians by recommending the best treatment strategy based on patient data and AI technologies.

Health Care · New York$50.0M Series B
Horizon3.ai
August 2026

Horizon3.ai offers an autonomous penetration testing platform that helps organizations proactively find and fix security vulnerabilities.

Artificial Intelligence (AI) · San Francisco$250.0M Series E
Farsight
July 2026

Farsight is an AI company that builds workflow automation tools for financial and insurance data processing.

Artificial Intelligence (AI) · New York$16.0M Corporate Round
Cordant
July 2026

Cordant is the command center for modern financial infrastructure and real-time money movement.

Blockchain · New York$8.0M Seed
Pure
July 2026

Pure is a legal, compliant, and rake-free real-money poker app designed for hosting private gameswithin trusted social networks.

Software · San Francisco$8.0M Seed
Swsh
June 2026

Swsh is a social app that aims to strengthen true friendships rather than superficial relationships with followers.

Social Media · New York$4.0M Seed
Billables AI
June 2026

Automated legal time-tracking, personalized and powered by AI.

Accounting · San Francisco$10.2M Series A
SuperDial
May 2026

SuperDial uses voice AI to automate high-volume phone calls across healthcare, reducing admin burden and boosting operational efficiency.

Artificial Intelligence (AI) · San FranciscoSeries B
Blank Bio
May 2026

Blank Bio is an applied AI research company developing RNA foundation models that analyze biological sequence data for therapeutic research.

Artificial Intelligence (AI) · San FranciscoSeed
Vector
May 2026

Vector helps B2B sales reps and SDRs generate pipeline by activating company's network avoiding cold prospecting and screaming into a void.

B2B · Boston$10.0M Series A
CopilotKit
May 2026

CopilotKit is the full-stack framework for building user interactive agents and copilots. The company behind the AG-UI Protocol.

Developer Platform · Seattle$20.5M Series A
Fun
May 2026

Fun develops payment infrastructure designed for web3 and digital asset transactions.

Apps · San Francisco$72.0M Series A
Shade
April 2026

Shade develops a private AI-driven file explorer that visually searches and previews terabytes of files.

Artificial Intelligence (AI) · New York$14.0M Venture - Series Unknown
Patlytics
April 2026

Patlytics provides AI-driven patent intelligence solutions to enhance research and efficiency.

Artificial Intelligence (AI) · San Francisco$40.5M Series B
TestBox
March 2026

TestBox create AI-powered demo and POC environments with custom data that mirrors your prospect's business, closing deals faster.

Artificial Intelligence (AI) · San Francisco$12.0M Series A
Moxie
March 2026

Moxie provides comprehensive software for managing MedSpa operations, including compliance, marketing, and patient management.

Health Care · New York$25.0M Series C
Affiniti
March 2026

Affiniti Fueling Small Businesses Across America With Industry-Tailored Credit Cards.

Banking · New YorkCorporate Round
Mega
March 2026

Mega is an AI marketing platform that automates SEO and digital advertising for businesses.

Artificial Intelligence (AI) · Brooklyn$11.5M Series A
Aura
February 2026

Aura provides AI-powered security solutions that offer identity theft protection, credit monitoring, and online privacy for individuals.

Artificial Intelligence (AI) · Boston$75.0M Venture - Series Unknown
Moody Pines
January 2026

Moodypines is a voice AI agency providing talent, datasets, and services for AI voice technology projects.

Artificial Intelligence (AI) · New York$1.8M Pre-Seed
Prudentia Sciences
January 2026

Prudentia Sciences is a platform enables AI-powered Asset Diligence and Valuation to De-Risk Investment in Drug Development.

Artificial Intelligence (AI) · Cambridge$20.0M Series A
Ply
December 2025

Ply develops a materials procurement platform to assist skilled trades with capital access and cash flow management.

Building Material · New York$8.5M Venture - Series Unknown

Where SignalFire invests

Artificial Intelligence (AI)14
Software9
Information Technology7
Financial Services5
SaaS4
Health Care3

About SignalFire's portfolio

How many companies has SignalFire invested in?▸

SignalFire has invested in 211 companies tracked in our database. The portfolio spans multiple industries and funding stages, from seed-stage startups to late-stage companies.

What industries does SignalFire invest in?▸

SignalFire's top investment sectors include Artificial Intelligence (AI), Software, Information Technology, Financial Services, SaaS. The firm invests across 50 different industry categories.

What is SignalFire's largest investment?▸

Among tracked funding rounds, Horizon3.ai received $250.0M in a Series E round. SignalFire's total known invested capital is $4.5B.

What is the average investment size for SignalFire?▸

SignalFire's average investment size is $21.2M across its portfolio of 211 companies.

What are SignalFire's most recent investments?▸

Recent SignalFire portfolio additions include Preference Model, Outmarket AI, Flagler Health, Horizon3.ai, Farsight. These companies were founded in 2020 or later.

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