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Two Sigma Ventures — Portfolio, Page 3

Investor actively backing innovative startups and growth-stage companies across various industries and funding rounds.

116
Companies
$3.2B
Total invested
$40.0M
Avg. check
63
Industries
Artificial Intelligence (AI) 9Software 8Information Technology 5Analytics 3Machine Learning 3Biotechnology 3+57 more
Founder contacts

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Portfolio companies

Showing 4972 of 116
MonetizeNow
November 2021

MonetizeNow is the World's First Unified CPQ, Billing and Usage Platform Built For B2B SaaS

Billing · Santa Clara$3.0M Seed
Indico Data
October 2025

Indico Data provides machine learning solutions for automating data extraction and analysis from unstructured content.

Analytics · BostonVenture - Series Unknown
Hexagon Bio
October 2022

Hexagon Bio is a data-driven biotech company developing targeted small molecule therapeutics.

Biotechnology · Menlo Park$77.3M Series B
Crossover Markets Group
March 2026

Crossover Markets is a digital asset trading technology company that meets the liquidity requirements of institutional investors.

Finance · London$31.0M Series B
Nullify
February 2026

Nullify is a cybersecurity technology company that provides an autonomous AI-powered workforce to automate product security tasks.

Artificial Intelligence (AI) · Sydney$12.5M Seed
WHOOP
January 2026

WHOOP is a fitness tech company that offers wearables that track sleep, recovery, and performance.

Consumer Electronics · BostonUndisclosed
Etched.ai
January 2026

Etched.ai is an AI chip startup that develops Sohu, a chip designed specifically for running transformer models.

AI Infrastructure · Cupertino$500.0M Series Unknown
Freeform
January 2026

Freeform is a 3D printing company offering metal 3D printing solutions for manufacturing companies.

3D Technology · Los Angeles$67.0M Series B
Cylera
December 2025

Cylera is a healthcare IoT cybersecurity and intelligence company used to protect healthcare organizations.

Analytics · New YorkConvertible Note
Pryon
December 2025

Pryon is an enterprise knowledge management platform designed to simplify and accelerate the adoption of artificial intelligence.

Artificial Intelligence (AI) · RaleighConvertible Note
Rive
December 2025

Rive is a real-time animation software provider.

Animation · San Francisco$453K Series A
Cosmos Innovation
November 2025

Cosmos Innovation specialize in full stack software development, product design, cloud hosting, and MVP deployment.

Artificial Intelligence (AI) · SeattleSeries Unknown
Cerby
September 2025

Cerby is the identity automation platform for disconnected apps

Cloud Security · San FranciscoSeries B
Enveda Biosciences
September 2025

Enveda Biosciences is a biotechnology company that develops novel medications derived from plants.

Biotechnology · Boulder$150.0M Series D
Dakota Ridge
July 2025

Dakota Ridge is a fintech firm that provides banking services for crypto businesses.

Cryptocurrency · Boulder$12.5M Series A
NetBox Labs
July 2025

NetBox Labs helps teams create and manage complex networks and infrastructure.

AI Infrastructure · New York$35.0M Series B
Compound Eye
May 2025

Compound Eye develops 3D vision systems for autonomous machines.

3D Technology · Redwood City$12.8M Series Unknown
RightRev
May 2025

RightRev provides software for revenue recognition that helps to track revenue contracts, quote, orders, invoices, and management reporting.

Finance · Santa Clara$13.0M Series A
Steadily
April 2025

Steadily provides property and liability insurance for rental property owners and investors.

Commercial Insurance · Beaverton$30.0M Series C
Terray Therapeutics
April 2025

Terray Therapeutics is a biotechnology company that transforms small molecule drug discovery.

Artificial Intelligence (AI) · Monrovia$25.0M Debt Financing
Anomalo
November 2024

Anomalo allows users to continuously inspect and validate the data coming into their warehouses.

Data Management · Palo Alto$10.0M Series B
Distributional
October 2024

Distributional offers a tech platform for enterprise AI testing and evaluation to make AI safe, reliable, and secure.

A/B Testing · Berkeley$19.0M Series A
Omni Network
September 2024

Omni Network is a blockchain that supports applications in functioning across all rollups.

Blockchain · New York$500K Series Unknown
SDF
June 2024

SDF is a compiler and build system that leverages static analysis to comprehensively examine SQL code at a warehouse scale.

Analytics · Los Angeles$9.0M Seed

Where Two Sigma Ventures invests

Artificial Intelligence (AI)9
Software8
Information Technology5
Analytics3
Machine Learning3
Biotechnology3

About Two Sigma Ventures's portfolio

How many companies has Two Sigma Ventures invested in?

Two Sigma Ventures has invested in 116 companies tracked in our database. The portfolio spans multiple industries and funding stages, from seed-stage startups to late-stage companies.

What industries does Two Sigma Ventures invest in?

Two Sigma Ventures's top investment sectors include Artificial Intelligence (AI), Software, Information Technology, Analytics, Machine Learning. The firm invests across 63 different industry categories.

What is Two Sigma Ventures's largest investment?

Among tracked funding rounds, Etched.ai received $500.0M in a Series Unknown round. Two Sigma Ventures's total known invested capital is $3.2B.

What is the average investment size for Two Sigma Ventures?

Two Sigma Ventures's average investment size is $40.0M across its portfolio of 116 companies.

What are Two Sigma Ventures's most recent investments?

Recent Two Sigma Ventures portfolio additions include MonetizeNow, Indico Data, Hexagon Bio, Crossover Markets Group, Nullify. These companies were founded in 2020 or later.

Reach the founders behind these 116 companies
Verified emails and LinkedIn profiles, updated monthly.
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