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5AM Ventures — Portfolio

Investor actively backing innovative startups and growth-stage companies across various industries and funding rounds.

68
Companies
$7.2B
Total invested
$124.4M
Avg. check
20
Industries
Biotechnology 20Health Care 14Medical 9Therapeutics 8Life Science 6Biopharma 4+14 more
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Portfolio companies

Showing 124 of 68
Deverra Therapeutics
September 2024

Deverra Therapeutics is a biotechnology company that develops allogeneic cellular immunotherapies.

Biotechnology · Seattle$972K Equity Crowdfunding
Nvelop Therapeutics
September 2023

Nvelop Therapeutics is a biotechnology company that developes genetic medicines for patients with severe genetic diseases.

Biotechnology · Cambridge$100.0M Seed
Novome Biotechnologies
September 2022

Novome Biotechnologies is a biotechnology company focused on engineering defined activities into the human.

Biopharma · South San Francisco$43.5M Series B
scPharmaceuticals
August 2024

ScPharmaceuticals is a biopharmaceutical company developing a portfolio of transformative pharmaceutical products for subcutaneous delivery.

Biotechnology · Lexington$125.0M Post-IPO Debt
Renasant Bio
July 2025

Renasant Bio is a biopharmaceutical company pioneering disease-modifying oral small molecule treatments.

Biotechnology · Berkeley$54.5M Seed
IDEAYA Biosciences
June 2026

IDEAYA Biosciences is an oncology-focused biotechnology company that develops therapeutics for patients with genetically-defined cancers.

Biotechnology · South San Francisco$345.0M Post-IPO Equity
Enliven Therapeutics
June 2026

Enliven Therapeutics is a precision oncology company developing small molecule therapies to extend and improve patient lives.

Biotechnology · Boulder$460.0M Post-IPO Equity
Bioz
May 2024

Bioz is a disruptive startup at the intersection of information technology and scientific research.

Artificial Intelligence (AI) · Palo AltoVenture - Series Unknown
Portal Instruments
April 2022

Portal Instruments is an early stage company that offers medical device.

Health Care · Cambridge$7.0M Venture - Series Unknown
Rallybio
April 2024

Rallybio is an biotechnological research and development services intended to transform the lives of patients with a devastating disease.

Biopharma · Farmington$6.6M Post-IPO Equity
Surrozen
March 2025

Surrozen is a biopharmaceutical that focuses on unlocking the body’s regenerative power to treat injury and disease.

Biotechnology · South San Francisco$175.0M Post-IPO Equity
Tectonic Therapeutic
February 2025

Tectonic Therapeutic is a biotechnology company which focuses on scientific research in biochemistry and molecular pharmacology.

Biotechnology · Watertown$185.0M Post-IPO Equity
MapLight Therapeutics
July 2025

MapLight Therapeutics is a biopharma company that offers a platform designed to discover and develop therapeutics for brain disorders.

Biopharma · Palo Alto$372.5M Series D
Fellow Health
July 2025

Fellow Health provides peer-reviewed, clinical semen analysis solutions that patients can conveniently perform at home.

Fertility · San Francisco$24.0M Series B
GlycoEra
May 2025

GlycoEra is a biotechnology research company that produces extracellular protein degraders for the treatment of autoimmune diseases.

Biotechnology · Schlieren$130.0M Series B
TMRW Life Sciences
July 2024

TMRW Life Sciences provides an integrated platform for automated, software-guided cryospecimen management.

Biotechnology · New York$28.2M Series D
Magnetic Insight
July 2024

Magnetic Insight is a biotechnology company that offers cellular imaging to measure the efficacy of cancer immunotherapies.

Biotechnology · AlamedaSeries B
RareCyte
June 2024

RareCyte is a life science research and diagnostic development company focused on characterizing and isolating rare cells in the blood.

Biotechnology · Seattle$20.0M Venture - Series Unknown
Nouscom
March 2024

Nouscom is a biotech company that develops a series of immunotherapies that are capable of selectively killing tumor cells.

Biotechnology · Basel$7.6M Series C
Radionetics Oncology
August 2023

Radionetics Oncology is a pharmaceutical company that focuses on the discovery and development of novel radiotherapeutics.

Health Care · California City$52.5M Series A
Nido Biosciences
May 2023

Nido Biosciences is a clinical-stage company that develops precision medicines for severe neurological diseases.

Biotechnology · Watertown$86.6M Series B
Expansion Therapeutics
January 2023

Expansion Therapeutics is a biotechnology company focusing on developing transformative oral medicines for severe RNA-mediated diseases.

Biotechnology · San Diego$6.9M Venture - Series Unknown
Skye Bioscience
January 2024

Skye Bioscience is a pharmaceutical company developing new therapeutic outcomes for diseases.

Biotechnology · San Diego$50.3M Post-IPO Equity
Mendra
January 2026

Mendra uses AI to accelerate clinical development and commercialization of breakthrough medicines for diseases with high unmet need.

Artificial Intelligence (AI) · San Francisco$82.0M Series A

Where 5AM Ventures invests

Biotechnology20
Health Care14
Medical9
Therapeutics8
Life Science6
Biopharma4

About 5AM Ventures's portfolio

How many companies has 5AM Ventures invested in?

5AM Ventures has invested in 68 companies tracked in our database. The portfolio spans multiple industries and funding stages, from seed-stage startups to late-stage companies.

What industries does 5AM Ventures invest in?

5AM Ventures's top investment sectors include Biotechnology, Health Care, Medical, Therapeutics, Life Science. The firm invests across 20 different industry categories.

What is 5AM Ventures's largest investment?

Among tracked funding rounds, Enliven Therapeutics received $460.0M in a Post-IPO Equity round. 5AM Ventures's total known invested capital is $7.2B.

What is the average investment size for 5AM Ventures?

5AM Ventures's average investment size is $124.4M across its portfolio of 68 companies.

What are 5AM Ventures's most recent investments?

Recent 5AM Ventures portfolio additions include Deverra Therapeutics, Nvelop Therapeutics, Novome Biotechnologies, scPharmaceuticals, Renasant Bio. These companies were founded in 2020 or later.

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