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5AM Ventures — Portfolio

Investor actively backing innovative startups and growth-stage companies across various industries and funding rounds.

66
Companies
$5.4B
Total invested
$82.5M
Avg. check
29
Industries
Biotechnology 19Health Care 15Therapeutics 8Medical 8Life Science 6Oncology 3+23 more
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Portfolio companies

Showing 1–24 of 66
Enliven Therapeutics
June 2026

Enliven Therapeutics is a precision oncology company developing small molecule therapies to extend and improve patient lives.

Biotechnology · Boulder$460.0M Post-IPO Equity
IDEAYA Biosciences
June 2026

IDEAYA Biosciences is an oncology-focused biotechnology company that develops therapeutics for patients with genetically-defined cancers.

Biotechnology · South San Francisco$345.0M Post-IPO Equity
Mendra
January 2026

Mendra uses AI to accelerate clinical development and commercialization of breakthrough medicines for diseases with high unmet need.

Artificial Intelligence (AI) · San Francisco$82.0M Series A
Precede Biosciences
January 2026

Precede Biosciences is a biotechnology company that provides a blood-based approach to reveal disease-defining transcriptional biology.

Biopharma · Boston$63.5M Series B
Kinaset Therapeutics
January 2026

Kinaset Therapeutics is a biopharma company that focuses on advancement of novel drugs in areas of unmet medical needs.

Health Care · Boston$103.0M Series B
ProLynx
December 2025

ProLynx is a biotechnology company that develops proprietary drug-delivery technologies to extend the half-life of therapeutic molecules.

Biotechnology · San Francisco$70.0M Series A
Lifordi Immunotherapeutics
November 2025

Lifordi Immunotherapeutics is a biotech company that provides antibody-drug conjugates for autoimmune and inflammatory disorders.

Biotechnology · Burlington$42.0M Venture - Series Unknown
Fellow Health
July 2025

Fellow Health provides peer-reviewed, clinical semen analysis solutions that patients can conveniently perform at home.

Fertility · San Francisco$24.0M Series B
Renasant Bio
July 2025

Renasant Bio is a biopharmaceutical company pioneering disease-modifying oral small molecule treatments.

Biotechnology · Berkeley$54.5M Seed
GlycoEra
May 2025

GlycoEra is a biotechnology research company that produces extracellular protein degraders for the treatment of autoimmune diseases.

Biotechnology · Schlieren$130.0M Series B
Surrozen
March 2025

Surrozen is a biopharmaceutical that focuses on unlocking the body’s regenerative power to treat injury and disease.

Biotechnology · South San Francisco$175.0M Post-IPO Equity
Tectonic Therapeutic
February 2025

Tectonic Therapeutic is a biotechnology company which focuses on scientific research in biochemistry and molecular pharmacology.

Biotechnology · Watertown$185.0M Post-IPO Equity
Deverra Therapeutics
September 2024

Deverra Therapeutics is a biotechnology company that develops allogeneic cellular immunotherapies.

Biotechnology · Seattle$972K Equity Crowdfunding
scPharmaceuticals
August 2024

ScPharmaceuticals is a biopharmaceutical company developing a portfolio of transformative pharmaceutical products for subcutaneous delivery.

Biotechnology · Lexington$125.0M Post-IPO Debt
TMRW Life Sciences
July 2024

TMRW Life Sciences provides an integrated platform for automated, software-guided cryospecimen management.

Biotechnology · New York$28.2M Series D
Magnetic Insight
July 2024

Magnetic Insight is a biotechnology company that offers cellular imaging to measure the efficacy of cancer immunotherapies.

Biotechnology · AlamedaSeries B
RareCyte
June 2024

RareCyte is a life science research and diagnostic development company focused on characterizing and isolating rare cells in the blood.

Biotechnology · Seattle$20.0M Venture - Series Unknown
Bioz
May 2024

Bioz is a disruptive startup at the intersection of information technology and scientific research.

Artificial Intelligence (AI) · Palo AltoVenture - Series Unknown
Rallybio
April 2024

Rallybio is an biotechnological research and development services intended to transform the lives of patients with a devastating disease.

Biopharma · Farmington$6.6M Post-IPO Equity
Skye Bioscience
January 2024

Skye Bioscience is a pharmaceutical company developing new therapeutic outcomes for diseases.

Biotechnology · San Diego$50.3M Post-IPO Equity
Halio
November 2023

Halio is developing adaptive, dynamic glass for the commercial, residential, and automotive markets.

Advanced Materials · Hayward$70.0M Corporate Round
Nvelop Therapeutics
September 2023

Nvelop Therapeutics is a biotechnology company that developes genetic medicines for patients with severe genetic diseases.

Biotechnology · Cambridge$100.0M Seed
Radionetics Oncology
August 2023

Radionetics Oncology is a pharmaceutical company that focuses on the discovery and development of novel radiotherapeutics.

Health Care · California City$52.5M Series A
Nido Biosciences
May 2023

Nido Biosciences is a clinical-stage company that develops precision medicines for severe neurological diseases.

Biotechnology · Watertown$86.6M Series B

Where 5AM Ventures invests

Biotechnology19
Health Care15
Therapeutics8
Medical8
Life Science6
Oncology3

About 5AM Ventures's portfolio

How many companies has 5AM Ventures invested in?▸

5AM Ventures has invested in 66 companies tracked in our database. The portfolio spans multiple industries and funding stages, from seed-stage startups to late-stage companies.

What industries does 5AM Ventures invest in?▸

5AM Ventures's top investment sectors include Biotechnology, Health Care, Therapeutics, Medical, Life Science. The firm invests across 29 different industry categories.

What is 5AM Ventures's largest investment?▸

Among tracked funding rounds, Enliven Therapeutics received $460.0M in a Post-IPO Equity round. 5AM Ventures's total known invested capital is $5.4B.

What is the average investment size for 5AM Ventures?▸

5AM Ventures's average investment size is $82.5M across its portfolio of 66 companies.

What are 5AM Ventures's most recent investments?▸

Recent 5AM Ventures portfolio additions include Enliven Therapeutics, IDEAYA Biosciences, Mendra, Precede Biosciences, Kinaset Therapeutics. These companies were founded in 2020 or later.

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