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5AM Ventures — Portfolio, Page 2

Investor actively backing innovative startups and growth-stage companies across various industries and funding rounds.

66
Companies
$5.4B
Total invested
$82.5M
Avg. check
18
Industries
Biotechnology 20Health Care 16Medical 10Therapeutics 9Biopharma 5Pharmaceutical 5+12 more
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Portfolio companies

Showing 25–48 of 66
Expansion Therapeutics
January 2023

Expansion Therapeutics is a biotechnology company focusing on developing transformative oral medicines for severe RNA-mediated diseases.

Biotechnology · San Diego$6.9M Venture - Series Unknown
Novome Biotechnologies
September 2022

Novome Biotechnologies is a biotechnology company focused on engineering defined activities into the human.

Biopharma · South San Francisco$43.5M Series B
Portal Instruments
April 2022

Portal Instruments is an early stage company that offers medical device.

Health Care · Cambridge$7.0M Venture - Series Unknown
Mendra
January 2026

Mendra uses AI to accelerate clinical development and commercialization of breakthrough medicines for diseases with high unmet need.

Artificial Intelligence (AI) · San Francisco$82.0M Series A
Spruce Biosciences
January 2026

Spruce Biosciences is a biopharmaceutical company developing therapies for rare diseases that target the endocrine system.

Biopharma · South San FranciscoPost Ipo Equity
Lifordi Immunotherapeutics
November 2025

Lifordi Immunotherapeutics is a biotech company that provides antibody-drug conjugates for autoimmune and inflammatory disorders.

Biotechnology · Burlington$42.0M Series Unknown
MapLight Therapeutics
July 2025

MapLight Therapeutics is a biopharma company that offers a platform designed to discover and develop therapeutics for brain disorders.

Biopharma · Palo Alto$372.5M Series D
Fellow Health
July 2025

Fellow Health provides peer-reviewed, clinical semen analysis solutions that patients can conveniently perform at home.

Fertility · San Francisco$24.0M Series B
Renasant Bio
July 2025

Renasant Bio is a biopharmaceutical company pioneering disease-modifying oral small molecule treatments.

Biotechnology · Berkeley$54.5M Seed
GlycoEra
May 2025

GlycoEra is a biotechnology research company that produces extracellular protein degraders for the treatment of autoimmune diseases.

Biotechnology · Schlieren$130.0M Series B
Surrozen
March 2025

Surrozen is a biopharmaceutical that focuses on unlocking the body’s regenerative power to treat injury and disease.

Biotechnology · South San Francisco$175.0M Post Ipo Equity
Latigo Biotherapeutics
March 2025

Latigo Biotherapeutics is a clinical-stage biotechnology company that develops novel, non-opioid therapies for chronic pain.

Biotechnology · Thousand Oaks$150.0M Series B
Tectonic Therapeutic
February 2025

Tectonic Therapeutic is a biotechnology company which focuses on scientific research in biochemistry and molecular pharmacology.

Biotechnology · Watertown$185.0M Post Ipo Equity
scPharmaceuticals
August 2024

ScPharmaceuticals is a biopharmaceutical company developing a portfolio of transformative pharmaceutical products for subcutaneous delivery.

Biotechnology · Lexington$125.0M Post Ipo Debt
Magnetic Insight
July 2024

Magnetic Insight is a biotechnology company that offers cellular imaging to measure the efficacy of cancer immunotherapies.

Biotechnology · AlamedaSeries B
IDEAYA Biosciences
July 2024

IDEAYA Biosciences is an oncology-focused biotechnology company that develops therapeutics for patients with genetically-defined cancers.

Biotechnology · South San Francisco$263.0M Post Ipo Equity
Entrada Therapeutics
June 2024

Entrada Therapeutics is a developer of novel therapeutics intended to treat devastating diseases.

Biotechnology · Boston$100.0M Post Ipo Equity
Bioz
May 2024

Bioz is a disruptive startup at the intersection of information technology and scientific research.

Biotechnology · Palo AltoSeries Unknown
Karius
May 2024

Karius delivers genomic insights into infectious diseases, helping clinicians make critical, life-saving treatment decisions.

Biotechnology · Redwood City$100.0M Series C
Rallybio
April 2024

Rallybio is an biotechnological research and development services intended to transform the lives of patients with a devastating disease.

Biopharma · Farmington$6.6M Post Ipo Equity
Nouscom
March 2024

Nouscom is a biotech company that develops a series of immunotherapies that are capable of selectively killing tumor cells.

Biotechnology · Basel$7.6M Series C
Skye Bioscience
January 2024

Skye Bioscience is a pharmaceutical company developing new therapeutic outcomes for diseases.

Biotechnology · San Diego$50.3M Post Ipo Equity
Nvelop Therapeutics
September 2023

Nvelop Therapeutics is a biotechnology company that developes genetic medicines for patients with severe genetic diseases.

Biotechnology · Cambridge$100.0M Seed
Radionetics Oncology
August 2023

Radionetics Oncology is a pharmaceutical company that focuses on the discovery and development of novel radiotherapeutics.

Health Care · California City$52.5M Series A

Where 5AM Ventures invests

Biotechnology20
Health Care16
Medical10
Therapeutics9
Biopharma5
Pharmaceutical5

About 5AM Ventures's portfolio

How many companies has 5AM Ventures invested in?▸

5AM Ventures has invested in 66 companies tracked in our database. The portfolio spans multiple industries and funding stages, from seed-stage startups to late-stage companies.

What industries does 5AM Ventures invest in?▸

5AM Ventures's top investment sectors include Biotechnology, Health Care, Medical, Therapeutics, Biopharma. The firm invests across 18 different industry categories.

What is 5AM Ventures's largest investment?▸

Among tracked funding rounds, MapLight Therapeutics received $372.5M in a Series D round. 5AM Ventures's total known invested capital is $5.4B.

What is the average investment size for 5AM Ventures?▸

5AM Ventures's average investment size is $82.5M across its portfolio of 66 companies.

What are 5AM Ventures's most recent investments?▸

Recent 5AM Ventures portfolio additions include Expansion Therapeutics, Novome Biotechnologies, Portal Instruments, Mendra, Spruce Biosciences. These companies were founded in 2020 or later.

Reach the founders behind these 66 companies
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