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5AM Ventures — Portfolio, Page 2

Investor actively backing innovative startups and growth-stage companies across various industries and funding rounds.

68
Companies
$5.6B
Total invested
$107.3M
Avg. check
27
Industries
Biotechnology 20Health Care 16Medical 9Therapeutics 8Life Science 6Biopharma 5+21 more
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Portfolio companies

Showing 2548 of 68
ProLynx
December 2025

ProLynx is a biotechnology company that develops proprietary drug-delivery technologies to extend the half-life of therapeutic molecules.

Biotechnology · San Francisco$70.0M Series A
Precede Biosciences
January 2026

Precede Biosciences is a biotechnology company that provides a blood-based approach to reveal disease-defining transcriptional biology.

Biopharma · Boston$63.5M Series B
Lifordi Immunotherapeutics
November 2025

Lifordi Immunotherapeutics is a biotech company that provides antibody-drug conjugates for autoimmune and inflammatory disorders.

Biotechnology · Burlington$42.0M Venture - Series Unknown
Halio
November 2023

Halio is developing adaptive, dynamic glass for the commercial, residential, and automotive markets.

Advanced Materials · Hayward$70.0M Corporate Round
Kinaset Therapeutics
January 2026

Kinaset Therapeutics is a biopharma company that focuses on advancement of novel drugs in areas of unmet medical needs.

Health Care · Boston$103.0M Series B
Mendra
January 2026

Mendra uses AI to accelerate clinical development and commercialization of breakthrough medicines for diseases with high unmet need.

Artificial Intelligence (AI) · San Francisco$82.0M Series A
Spruce Biosciences
January 2026

Spruce Biosciences is a biopharmaceutical company developing therapies for rare diseases that target the endocrine system.

Biopharma · South San FranciscoPost Ipo Equity
MapLight Therapeutics
July 2025

MapLight Therapeutics is a biopharma company that offers a platform designed to discover and develop therapeutics for brain disorders.

Biopharma · Palo Alto$372.5M Series D
Fellow Health
July 2025

Fellow Health provides peer-reviewed, clinical semen analysis solutions that patients can conveniently perform at home.

Fertility · San Francisco$24.0M Series B
Renasant Bio
July 2025

Renasant Bio is a biopharmaceutical company pioneering disease-modifying oral small molecule treatments.

Biotechnology · Berkeley$54.5M Seed
GlycoEra
May 2025

GlycoEra is a biotechnology research company that produces extracellular protein degraders for the treatment of autoimmune diseases.

Biotechnology · Schlieren$130.0M Series B
Surrozen
March 2025

Surrozen is a biopharmaceutical that focuses on unlocking the body’s regenerative power to treat injury and disease.

Biotechnology · South San Francisco$175.0M Post Ipo Equity
Latigo Biotherapeutics
March 2025

Latigo Biotherapeutics is a clinical-stage biotechnology company that develops novel, non-opioid therapies for chronic pain.

Biotechnology · Thousand Oaks$150.0M Series B
Tectonic Therapeutic
February 2025

Tectonic Therapeutic is a biotechnology company which focuses on scientific research in biochemistry and molecular pharmacology.

Biotechnology · Watertown$185.0M Post Ipo Equity
scPharmaceuticals
August 2024

ScPharmaceuticals is a biopharmaceutical company developing a portfolio of transformative pharmaceutical products for subcutaneous delivery.

Biotechnology · Lexington$125.0M Post Ipo Debt
Magnetic Insight
July 2024

Magnetic Insight is a biotechnology company that offers cellular imaging to measure the efficacy of cancer immunotherapies.

Biotechnology · AlamedaSeries B
IDEAYA Biosciences
July 2024

IDEAYA Biosciences is an oncology-focused biotechnology company that develops therapeutics for patients with genetically-defined cancers.

Biotechnology · South San Francisco$263.0M Post Ipo Equity
Entrada Therapeutics
June 2024

Entrada Therapeutics is a developer of novel therapeutics intended to treat devastating diseases.

Biotechnology · Boston$100.0M Post Ipo Equity
Bioz
May 2024

Bioz is a disruptive startup at the intersection of information technology and scientific research.

Biotechnology · Palo AltoSeries Unknown
Karius
May 2024

Karius delivers genomic insights into infectious diseases, helping clinicians make critical, life-saving treatment decisions.

Biotechnology · Redwood City$100.0M Series C
Rallybio
April 2024

Rallybio is an biotechnological research and development services intended to transform the lives of patients with a devastating disease.

Biopharma · Farmington$6.6M Post Ipo Equity
Nouscom
March 2024

Nouscom is a biotech company that develops a series of immunotherapies that are capable of selectively killing tumor cells.

Biotechnology · Basel$7.6M Series C
Skye Bioscience
January 2024

Skye Bioscience is a pharmaceutical company developing new therapeutic outcomes for diseases.

Biotechnology · San Diego$50.3M Post Ipo Equity
Nvelop Therapeutics
September 2023

Nvelop Therapeutics is a biotechnology company that developes genetic medicines for patients with severe genetic diseases.

Biotechnology · Cambridge$100.0M Seed

Where 5AM Ventures invests

Biotechnology20
Health Care16
Medical9
Therapeutics8
Life Science6
Biopharma5

About 5AM Ventures's portfolio

How many companies has 5AM Ventures invested in?

5AM Ventures has invested in 68 companies tracked in our database. The portfolio spans multiple industries and funding stages, from seed-stage startups to late-stage companies.

What industries does 5AM Ventures invest in?

5AM Ventures's top investment sectors include Biotechnology, Health Care, Medical, Therapeutics, Life Science. The firm invests across 27 different industry categories.

What is 5AM Ventures's largest investment?

Among tracked funding rounds, MapLight Therapeutics received $372.5M in a Series D round. 5AM Ventures's total known invested capital is $5.6B.

What is the average investment size for 5AM Ventures?

5AM Ventures's average investment size is $107.3M across its portfolio of 68 companies.

What are 5AM Ventures's most recent investments?

Recent 5AM Ventures portfolio additions include ProLynx, Precede Biosciences, Lifordi Immunotherapeutics, Halio, Kinaset Therapeutics. These companies were founded in 2020 or later.

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