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Adage Capital Management — Portfolio

Investor actively backing innovative startups and growth-stage companies across various industries and funding rounds.

73
Companies
$10.9B
Total invested
$148.9M
Avg. check
14
Industries
Biotechnology 24Therapeutics 14Health Care 13Pharmaceutical 9Biopharma 8Medical 4+8 more
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Portfolio companies

Showing 1–24 of 73
Helus Pharma
September 2026

Helus Pharma is a biopharmaceutical company that develops psychedelic therapeutics for mental health conditions.

Biotechnology · Toronto$50.0M Post-IPO Equity
LB Pharmaceuticals
July 2026

LB Pharmaceuticals specializes in developing LB-102 (n-Methyl amisulpride) as a treatment for schizophrenia.

Biopharma · New York$150.0M Post-IPO Equity
Shattuck Labs
June 2026

Shattuck Labs is a biotechnology company that provides novel class biologic medicines for the treatment of cancer and autoimmune disease.

Biopharma · Austin$75.0M Post-IPO Equity
Cabaletta Bio
May 2026

Cabaletta Bio has adapted clinically-validated and FDA-approved CAR T cell technology to target B cell-mediated autoimmune diseases.

Biotechnology · Philadelphia$150.0M Post-IPO Equity
Climb Bio
April 2026

Climb Bio occurs when the immune system mistakenly attacks the body's tissues and can result in permanent organ damage or even death.

Biotechnology · Redmond$110.0M Post-IPO Equity
Ray Therapeutics
April 2026

Ray Therapeutics is a biotech company that develops optogenetic gene therapies for patients with blinding diseases.

Biotechnology · San Diego$125.0M Series B
Trevi Therapeutics
April 2026

Trevi Therapeutics is a clinical-stage biopharmaceutical company that develops drugs for treating uremic pruritus.

Biotechnology · Sandy Hook$173.0M Post-IPO Equity
Spyre Therapeutics
April 2026

Spyre Therapeutics is a biotechnology business that is developing a strong pipeline of antibody therapies.

Biotechnology · Sunrise$403.0M Post-IPO Equity
Opus Genetics(formerly Ocuphire Pharma)
April 2026

Opus Genetics a clinical-stage biopharmaceutical company, develops and commercializes therapies for patients with ophthalmic disorders.

Biopharma · Farmington Hills$35.0M Post-IPO Debt
Palisade Bio
March 2026

Palisade Bio is a clinical-stage biopharmaceutical company that develops therapies for acute and chronic gastrointestinal complications.

Biopharma · Carlsbad$3.0M Post-IPO Equity
Equillium
March 2026

Equillium is a biotechnology company that develops products for autoimmune and inflammatory disorders with an unmet medical need.

Biopharma · La Jolla$35.0M Post-IPO Equity
Ambros Therapeutics
December 2025

Ambros Therapeutics is a clinical-stage biotechnology company.

Biotechnology · Irvine$125.0M Series A
Pasithea Therapeutics
November 2025

Pasithea Therapeutics is a biotechnology company that seeks to solve clinical problems such as mental health.

Biotechnology · Miami Beach$60.0M Post-IPO Equity
Cogent Biosciences
November 2025

Cogent Biosciences is a biotechnology company that develops therapies for solid cancer tumors.

Biotechnology · Waltham$200.0M Post-IPO Debt
Ultragenyx Pharmaceutical
November 2025

Ultragenyx Pharmaceutical focuses on the development of various products for the treatment of rare and ultra-rare diseases.

Biotechnology · Novato$400.0M Post-IPO Debt
Kailera Therapeutics
October 2025

Kailera Therapeutics develops next-generation injectable and oral therapies for chronic weight management.

Biotechnology · Waltham$600.0M Series B
Cidara Therapeutics
October 2025

Cidara Therapeutics develops targeted immunotherapies aimed at improving treatment outcomes for patients with serious diseases.

Biotechnology · San Diego$339.0M Grant
Monopar
September 2025

Monopar Therapeutics is an emerging biopharmaceutical company focused on developing orphan oncology compounds.

Biopharma · Wilmette$135.0M Post-IPO Equity
Arvinas
August 2025

Arvinas advances therapies degrading disease-causing proteins for life-threatening diseases, from discovery to commercialization.

Biotechnology · New HavenPost-IPO Equity
Tectonic Therapeutic
February 2025

Tectonic Therapeutic is a biotechnology company which focuses on scientific research in biochemistry and molecular pharmacology.

Biotechnology · Watertown$185.0M Post-IPO Equity
Ventyx Biosciences
September 2024

Ventyx is a biopharmaceutical company focused on advancing oral therapies for patients living with autoimmune and inflammatory disorders.

Biopharma · San Diego$27.0M Post-IPO Equity
Cullinan Therapeutics
April 2024

Cullinan Therapeutics is a developer of an externally sourced cancer therapeutics used to end a drug program quickly.

Biopharma · Cambridge$280.0M Post-IPO Equity
Akero Therapeutics
March 2024

Akero Therapeutics is a biotechnology company focused on reversing the NASH epidemic by restoring the body’s metabolism to a balanced state.

Biotechnology · Cambridge$366.9M Post-IPO Equity
Applied Therapeutics
February 2024

Applied Therapeutics uses drug-development approach to target molecules and pathways that has roles in fatal or debilitating diseases.

Biotechnology · New York$100.0M Post-IPO Equity

Where Adage Capital Management invests

Biotechnology24
Therapeutics14
Health Care13
Pharmaceutical9
Biopharma8
Medical4

About Adage Capital Management's portfolio

How many companies has Adage Capital Management invested in?▸

Adage Capital Management has invested in 73 companies tracked in our database. The portfolio spans multiple industries and funding stages, from seed-stage startups to late-stage companies.

What industries does Adage Capital Management invest in?▸

Adage Capital Management's top investment sectors include Biotechnology, Therapeutics, Health Care, Pharmaceutical, Biopharma. The firm invests across 14 different industry categories.

What is Adage Capital Management's largest investment?▸

Among tracked funding rounds, Kailera Therapeutics received $600.0M in a Series B round. Adage Capital Management's total known invested capital is $10.9B.

What is the average investment size for Adage Capital Management?▸

Adage Capital Management's average investment size is $148.9M across its portfolio of 73 companies.

What are Adage Capital Management's most recent investments?▸

Recent Adage Capital Management portfolio additions include Helus Pharma, LB Pharmaceuticals, Shattuck Labs, Cabaletta Bio, Climb Bio. These companies were founded in 2020 or later.

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