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Hercules Capital — Portfolio

Investor actively backing innovative startups and growth-stage companies across various industries and funding rounds.

67
Companies
$5.3B
Total invested
$97.1M
Avg. check
41
Industries
Biotechnology 13Pharmaceutical 6Health Care 6Software 5Artificial Intelligence (AI) 4Biopharma 4+35 more
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Portfolio companies

Showing 124 of 67
3Gtms
September 2021

3GTMS provides transportation management system software for shippers, brokers, and logistics service providers.

Automotive · Columbus$15.0M Private Equity
Snappt
August 2025

Snappt provides fraud detection and income verification software for multifamily property managers.

Enterprise Software · Los Angeles$50.0M Debt Financing
ZeroFox
August 2022

ZeroFox provides external cybersecurity solutions to help organizations identify, manage, and mitigate social media-based cyber threats.

Cyber Security · Baltimore$170.0M Post-IPO Equity
Alladapt Immunotherapeutics
August 2022

Alladapt Immunotherapeutics is a privately held biopharmaceutical company developing prescription therapeutics targeting food allergy.

Biotechnology · Menlo Park$50.0M Debt Financing
Udacity
August 2021

Udacity develops an online learning platform offering programs in artificial intelligence, machine learning, and robotics sector.

Artificial Intelligence (AI) · Mountain View$5.0M Venture - Series Unknown
Madrigal Pharmaceuticals
July 2025

Madrigal Pharmaceuticals is a biopharmaceutical company developing therapeutics for the treatment of cardiovascular-metabolic diseases.

Biopharma · Conshohocken$350.0M Post-IPO Debt
Eloxx
June 2026

Eloxx Pharmaceuticals is a clinical-stage biopharmaceutical company developing novel RNA-modulating drug candidates.

Biotechnology · Waltham$66.0M Post-IPO Equity
4D Molecular Therapeutics
June 2026

4D Molecular Therapeutics designs, develops, and commercializes transformative gene therapeutic products for unmet medical conditions.

Biotechnology · Emeryville$200.0M Post-IPO Debt
MoonLake Immunotherapeutics
June 2026

MoonLake Immunotherapeutics is a clinical-stage biopharmaceuticals company.

Biotechnology · Zug$200.0M Post-IPO Equity
Semperis
June 2024

Semperis is a developer of enterprise identity protection and cyber resilience for cross-cloud and hybrid environments.

Cyber Security · Hoboken$125.0M Debt Financing
Behavox
June 2026

Behavox is an AI-driven platform that enables you to aggregate, analyze, and act on your entire organization’s data.

Artificial Intelligence (AI) · London$173.2M Private Equity
Electric Hydrogen
May 2024

Electric Hydrogen develops electrolyzer technologies to enable abundant, low-cost, and clean hydrogen to replace fossil fuels.

Clean Energy · Natick$100.0M Debt Financing
Locus Biosciences
May 2022

Locus Biosciences develops CRISPR-engineered precision antibacterial platform designed to revolutionize the treatment of bacterial disease.

Biopharma · Morrisville$35.0M Series B
Axsome Therapeutics
May 2025

Axsome Therapeutics is a biopharmaceutical company that develops therapies for the management and treatment of neurological disorders.

Biopharma · New York$570.0M Post-IPO Debt
Main Street Health
April 2025

Main Street Health is a supplier of value-based, care-focused healthcare services designed to address rural wellness challenges.

Health Care · Nashville$32.1M Venture - Series Unknown
Lucira Health
February 2022

Lucira Health is a biotechnology company that offers disposable test kits to detect RNA and DNA of infectious diseases.

Biotechnology · Emeryville$80.0M Post-IPO Debt
Genetix Biotherapeutics Inc.
February 2025

Genetix Biotherapeutics develops and delivers approved gene therapies for severe rare genetic diseases like sickle cell.

Biotechnology · SomervillePrivate Equity
Esme Learning Solutions
February 2022

Esme Learning is transforming the world's workforce for the Fourth Industrial Revolution using AI.

Artificial Intelligence (AI) · Newton$15.0M Venture - Series Unknown
Provention Bio
February 2023

Provention Bio is a clinical stage biopharmaceutical dedicated to sourcing, developing, and commercializing novel therapeutics.

Biotechnology · Red Bank$35.0M Post-IPO Equity
Remodel Health
December 2024

Remodel Health delivers software to assist employers in managing health benefits and transitioning to ICHRA.

Employee Benefits · Indianapolis$100.0M Venture - Series Unknown
Phathom Pharmaceuticals
January 2026

Phathom Pharmaceuticals is a biopharmaceutical company.

Biotechnology · Florham Park$130.0M Post-IPO Equity
Hypercore
February 2026

Hypercore provides a cloud-based platform that manages loan portfolios from origination through repayment.

Analytics · Herzliya$13.5M Series A
Dyne Therapeutics
December 2025

Dyne Therapeutics is a developer of targeted therapies intended for serious muscle diseases.

Biotechnology · Cambridge$402.5M Post Ipo Equity
Verastem Oncology
November 2025

Verastem is a biopharmaceutical company developing new medicines to improve the lives of patients with RAS/MAPK pathway-driven cancers.

Biopharma · Needham$90.0M Post Ipo Equity

Where Hercules Capital invests

Biotechnology13
Pharmaceutical6
Health Care6
Software5
Artificial Intelligence (AI)4
Biopharma4

About Hercules Capital's portfolio

How many companies has Hercules Capital invested in?

Hercules Capital has invested in 67 companies tracked in our database. The portfolio spans multiple industries and funding stages, from seed-stage startups to late-stage companies.

What industries does Hercules Capital invest in?

Hercules Capital's top investment sectors include Biotechnology, Pharmaceutical, Health Care, Software, Artificial Intelligence (AI). The firm invests across 41 different industry categories.

What is Hercules Capital's largest investment?

Among tracked funding rounds, Axsome Therapeutics received $570.0M in a Post-IPO Debt round. Hercules Capital's total known invested capital is $5.3B.

What is the average investment size for Hercules Capital?

Hercules Capital's average investment size is $97.1M across its portfolio of 67 companies.

What are Hercules Capital's most recent investments?

Recent Hercules Capital portfolio additions include 3Gtms, Snappt, ZeroFox, Alladapt Immunotherapeutics, Udacity. These companies were founded in 2020 or later.

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