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Hercules Capital — Portfolio, Page 2

Investor actively backing innovative startups and growth-stage companies across various industries and funding rounds.

73
Companies
$8.2B
Total invested
$113.0M
Avg. check
45
Industries
Biotechnology 14Health Care 10Therapeutics 7Medical 5Artificial Intelligence (AI) 4Pharmaceutical 4+39 more
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Portfolio companies

Showing 25–48 of 73
Replimune Group
November 2024

Replimune Group develop the next generation of ‘oncolytic immunotherapies’ for the treatment of cancer.

Biotechnology · Woburn$140.0M Post-IPO Equity
RumbleON
November 2024

RumbleON provides an e-commerce platform that facilitates to sell, buy, trade pre-owned recreation vehicles.

Automotive · Irving$10.0M Post-IPO Equity
SynOx Therapeutics
October 2024

SynOx Therapeutics is a biotechnology research company that focused on developing the treatment of diffuse tenosynovial giant cell tumors.

Biotechnology · Dublin$92.0M Series B
Semperis
June 2024

Semperis is a developer of enterprise identity protection and cyber resilience for cross-cloud and hybrid environments.

Cyber Security · Hoboken$125.0M Debt Financing
Electric Hydrogen
May 2024

Electric Hydrogen develops electrolyzer technologies to enable abundant, low-cost, and clean hydrogen to replace fossil fuels.

Clean Energy · Natick$100.0M Debt Financing
Kura Oncology
January 2024

Kura Oncology, a biopharmaceutical company, advances a pipeline of precision medicines for the treatment of solid tumors and blood cancers.

Biopharma · La Jolla$150.0M Post-IPO Equity
Better Therapeutics
January 2024

Better Therapeutics develops prescription software for treating cardiometabolic diseases.

Artificial Intelligence (AI) · San Francisco$250K Post-IPO Equity
Sight Sciences
January 2024

Sight Sciences is a medical device company that uses a computer-based device designed for the treatment of eye disease.

Eyewear · Menlo Park$35.0M Post-IPO Debt
AmplifyBio
November 2023

AmplifyBio is a biotechnology company that develops and advances treatments and cures for disease via cutting-edge technology and research.

Biotechnology · West Jefferson$49.8M Venture - Series Unknown
Provention Bio
February 2023

Provention Bio is a clinical stage biopharmaceutical dedicated to sourcing, developing, and commercializing novel therapeutics.

Biotechnology · Red Bank$35.0M Post-IPO Equity
Oak Street Health
November 2022

Oak Street Health is a network of primary care centers for adults on Medicare.

Health Care · Chicago$300.0M Post-IPO Debt
Alladapt Immunotherapeutics
August 2022

Alladapt Immunotherapeutics is a privately held biopharmaceutical company developing prescription therapeutics targeting food allergy.

Biotechnology · Menlo Park$50.0M Debt Financing
ZeroFox
August 2022

ZeroFox provides external cybersecurity solutions to help organizations identify, manage, and mitigate social media-based cyber threats.

Cyber Security · Baltimore$170.0M Post-IPO Equity
Locus Biosciences
May 2022

Locus Biosciences develops CRISPR-engineered precision antibacterial platform designed to revolutionize the treatment of bacterial disease.

Biopharma · Morrisville$35.0M Series B
Esme Learning Solutions
February 2022

Esme Learning is transforming the world's workforce for the Fourth Industrial Revolution using AI.

Artificial Intelligence (AI) · Newton$15.0M Venture - Series Unknown
Lucira Health
February 2022

Lucira Health is a biotechnology company that offers disposable test kits to detect RNA and DNA of infectious diseases.

Biotechnology · Emeryville$80.0M Post-IPO Debt
NorthSea Therapeutics
December 2021

NorthSea Therapeutics is a clinical-stage biotech company developing first-in class, oral, structurally-engineered lipid therapeutics.

Biotechnology · Naarden$80.0M Series C
3Gtms
September 2021

3GTMS provides transportation management system software for shippers, brokers, and logistics service providers.

Automotive · Columbus$15.0M Private Equity
Udacity
August 2021

Udacity develops an online learning platform offering programs in artificial intelligence, machine learning, and robotics sector.

Artificial Intelligence (AI) · Mountain View$5.0M Venture - Series Unknown
Hypercore
February 2026

Hypercore provides a cloud-based platform that manages loan portfolios from origination through repayment.

Analytics · Herzliya$13.5M Series A
Dyne Therapeutics
December 2025

Dyne Therapeutics is a developer of targeted therapies intended for serious muscle diseases.

Biotechnology · Cambridge$402.5M Post Ipo Equity
Verastem Oncology
November 2025

Verastem is a biopharmaceutical company developing new medicines to improve the lives of patients with RAS/MAPK pathway-driven cancers.

Biopharma · Needham$90.0M Post Ipo Equity
MoonLake Immunotherapeutics
November 2025

MoonLake Immunotherapeutics is a clinical-stage biopharmaceuticals company.

Biotechnology · Zug$75.0M Post Ipo Equity
X4 Pharmaceuticals
October 2025

X4 Pharmaceuticals is a clinical-stage oncology company developing oral small molecule CXCR4 antagonists for the treatment.

Biotechnology · Cambridge$155.3M Post Ipo Equity

Where Hercules Capital invests

Biotechnology14
Health Care10
Therapeutics7
Medical5
Artificial Intelligence (AI)4
Pharmaceutical4

About Hercules Capital's portfolio

How many companies has Hercules Capital invested in?▸

Hercules Capital has invested in 73 companies tracked in our database. The portfolio spans multiple industries and funding stages, from seed-stage startups to late-stage companies.

What industries does Hercules Capital invest in?▸

Hercules Capital's top investment sectors include Biotechnology, Health Care, Therapeutics, Medical, Artificial Intelligence (AI). The firm invests across 45 different industry categories.

What is Hercules Capital's largest investment?▸

Among tracked funding rounds, Dyne Therapeutics received $402.5M in a Post Ipo Equity round. Hercules Capital's total known invested capital is $8.2B.

What is the average investment size for Hercules Capital?▸

Hercules Capital's average investment size is $113.0M across its portfolio of 73 companies.

What are Hercules Capital's most recent investments?▸

Recent Hercules Capital portfolio additions include Replimune Group, RumbleON, SynOx Therapeutics, Semperis, Electric Hydrogen. These companies were founded in 2020 or later.

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