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MassChallenge — Portfolio

Investor actively backing innovative startups and growth-stage companies across various industries and funding rounds.

1,237
Companies
$4.6B
Total invested
$5.3M
Avg. check
59
Industries
Health Care 9Medical Device 5Medical 4Artificial Intelligence (AI) 4Information Technology 4Clean Energy 2+53 more
Founder contacts

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Portfolio companies

Showing 124 of 1,237
Avitus Orthopaedics
September 2021

Avitus Orthopaedics is a medical device company developing novel instruments for minimally invasive surgery.

Health Care · Farmington$5.0M Venture - Series Unknown
TechnoCarbon
September 2022

TechnoCarbon is a cleantech SAS company.

Clean Energy · Vitrolles$792K Seed
Boundless Robotics
September 2022

On a mission to help people effortlessly grow 5% of their food by 2030.

Artificial Intelligence (AI) · Boston$1.2M Pre-Seed
Dauntless XR
September 2022

Dauntless is the developer of Katana XR and Aura, mixed reality applications used in enterprise, defense, aerospace and aviation.

Aerospace · Houston$1.5M Grant
Systemcredit
September 2021

Digital platform for small and medium business loans.

Consulting · Schlieren$536K Seed
NovaSignal
September 2021

NovaSignal is a medical technology company commercializing a robotic cerebral ultrasound system.

Artificial Intelligence (AI) · Los Angeles$37.0M Series C
Sunwealth Power
September 2025

Sunwealth Power is a renewable energy investment firm that manages and finances solar and storage installations.

Clean Energy · Cambridge$20.0M Debt Financing
CleanFiber
September 2025

CleanFiber makes high-performance carbon-negative building insulation from recycled corrugated cardboard.

Building Material · Buffalo$34.0M Venture - Series Unknown
Labby
September 2023

Labby converts a smartphone into a high-tech food/beverage analytics lab

Food and Beverage · BostonNon-equity Assistance
Waku
September 2025

Waku offers plant-based tonics for a healthy gut.

Food and Beverage · Boston$1.5M Seed
Akselos
September 2025

Akselos is a developer of digital twin technology designed to protect critical infrastructures.

Analytics · LausannePrivate Equity
Innsightful
September 2024

Innsightful develops products and digital tools to help manage an individual's stress and moods.

Artificial Intelligence (AI) · SunnyvaleNon-equity Assistance
Apolitical
September 2024

Apolitical is a global learning platform for government

Government · London$2.0M Grant
Folia Materials
September 2025

Folia Materials: using paper as a super material

Advanced Materials · New York$400K Venture - Series Unknown
Rialto Markets
September 2023

Rialto Markets operates a digital securities alternative trading system.

Consulting · New York$40K Equity Crowdfunding
SOAP Health
September 2022

SOAP's patented, clinically validated, AI powered patient intake combines early disease risk and symptom assessment to improve diagnosis

Artificial Intelligence (AI) · Boca Raton$2.0M Seed
AirDAO
September 2022

AirDAO is building the world’s first publicly verifiable and community-driven ecosystem to assure the quality, safety and origins of food

Information Services · Zug$2.0M Pre-Seed
Encora Therapeutics
September 2022

Encora helps people with neurodegenerative movement disorders regain independence and control in their lives.

Health Care · BostonGrant
Yotta Energy
September 2023

Yotta is a clean energy technology company developing modular solar-integrated battery storage for commercial buildings.

Energy · Austin$8.0M Venture - Series Unknown
GliaPharm
September 2024

GliaPharm is a Swiss-based biotechnology company that develops treatments for neurological and psychiatric disorders.

Biotechnology · GenevaGrant
Applied Bioplastics
September 2024

Applied Bioplastics manufactures bioplastics in retail, packaging, and medical industries to improve plastic recycling.

Agriculture · AustinConvertible Note
Pointz
September 2022

Pointz is a mobile mapping app that helps navigate bike and scooter riders through safe routes in cities.

Logistics · Providence$500K Pre-Seed
HeroSupport
September 2025

HeroSupport transforms imaging and/or treatment tables into personalized solutions.

Health Care · VeyrierGrant
EarlySight
September 2025

EarlySight start-up company is founded in order to accelerate the development and to bring the technology to clinics.

Health Care · Lausanne$3.9M Seed

Where MassChallenge invests

Health Care9
Medical Device5
Medical4
Artificial Intelligence (AI)4
Information Technology4
Clean Energy2

About MassChallenge's portfolio

How many companies has MassChallenge invested in?

MassChallenge has invested in 1,237 companies tracked in our database. The portfolio spans multiple industries and funding stages, from seed-stage startups to late-stage companies.

What industries does MassChallenge invest in?

MassChallenge's top investment sectors include Health Care, Medical Device, Medical, Artificial Intelligence (AI), Information Technology. The firm invests across 59 different industry categories.

What is MassChallenge's largest investment?

Among tracked funding rounds, NovaSignal received $37.0M in a Series C round. MassChallenge's total known invested capital is $4.6B.

What is the average investment size for MassChallenge?

MassChallenge's average investment size is $5.3M across its portfolio of 1,237 companies.

What are MassChallenge's most recent investments?

Recent MassChallenge portfolio additions include Avitus Orthopaedics, TechnoCarbon, Boundless Robotics, Dauntless XR, Systemcredit. These companies were founded in 2020 or later.

Reach the founders behind these 1,237 companies
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