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MassChallenge — Portfolio

Investor actively backing innovative startups and growth-stage companies across various industries and funding rounds.

1,232
Companies
$5.9B
Total invested
$7.0M
Avg. check
62
Industries
Health Care 9Information Technology 5Medical Device 5Medical 4Artificial Intelligence (AI) 4Biotechnology 3+56 more
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Portfolio companies

Showing 1–24 of 1,232
DynamiCare Health
September 2026

DynamiCare Health is a digital platform helping people monitor and reduce the use of drugs, opioids, alcohol, and tobacco.

Health Care · Boston$720K Venture - Series Unknown
Avitus Orthopaedics
September 2021

Avitus Orthopaedics is a medical device company developing novel instruments for minimally invasive surgery.

Health Care · Farmington$5.0M Venture - Series Unknown
INIA Biosciences
September 2026

INIA Biosciences develops non-invasive, home-administered, and closed-loop medical devices to manage chronic inflammatory diseases.

Biotechnology · Boston$1.5M Seed
Boundless Robotics
September 2022

On a mission to help people effortlessly grow 5% of their food by 2030.

Artificial Intelligence (AI) · Boston$1.2M Pre-Seed
TechnoCarbon
September 2022

TechnoCarbon is a cleantech SAS company.

Clean Energy · Vitrolles$792K Seed
Dauntless XR
September 2022

Dauntless is the developer of Katana XR and Aura, mixed reality applications used in enterprise, defense, aerospace and aviation.

Aerospace · Houston$1.5M Grant
Systemcredit
September 2021

Digital platform for small and medium business loans.

Consulting · Schlieren$536K Seed
NovaSignal
September 2021

NovaSignal is a medical technology company commercializing a robotic cerebral ultrasound system.

Artificial Intelligence (AI) · Los Angeles$37.0M Series C
Sunwealth Power
September 2025

Sunwealth Power is a renewable energy investment firm that manages and finances solar and storage installations.

Clean Energy · Cambridge$20.0M Debt Financing
Labby
September 2023

Labby converts a smartphone into a high-tech food/beverage analytics lab

Food and Beverage · BostonNon-equity Assistance
Akselos
September 2025

Akselos is a developer of digital twin technology designed to protect critical infrastructures.

Analytics · LausannePrivate Equity
Waku
September 2025

Waku offers plant-based tonics for a healthy gut.

Food and Beverage · Boston$1.5M Seed
Innsightful
September 2024

Innsightful develops products and digital tools to help manage an individual's stress and moods.

Artificial Intelligence (AI) · SunnyvaleNon-equity Assistance
Apolitical
September 2024

Apolitical is a global learning platform for government

Government · London$2.0M Grant
Folia Materials
September 2025

Folia Materials: using paper as a super material

Advanced Materials · New York$400K Venture - Series Unknown
Rialto Markets
September 2023

Rialto Markets operates a digital securities alternative trading system.

Consulting · New York$40K Equity Crowdfunding
SOAP Health
September 2022

SOAP's patented, clinically validated, AI powered patient intake combines early disease risk and symptom assessment to improve diagnosis

Artificial Intelligence (AI) · Boca Raton$2.0M Seed
AirDAO
September 2022

AirDAO is building the world’s first publicly verifiable and community-driven ecosystem to assure the quality, safety and origins of food

Information Services · Zug$2.0M Pre-Seed
Encora Therapeutics
September 2022

Encora helps people with neurodegenerative movement disorders regain independence and control in their lives.

Health Care · BostonGrant
Yotta Energy
September 2023

Yotta is a clean energy technology company developing modular solar-integrated battery storage for commercial buildings.

Energy · Austin$8.0M Venture - Series Unknown
GliaPharm
September 2024

GliaPharm is a Swiss-based biotechnology company that develops treatments for neurological and psychiatric disorders.

Biotechnology · GenevaGrant
Applied Bioplastics
September 2024

Applied Bioplastics manufactures bioplastics in retail, packaging, and medical industries to improve plastic recycling.

Agriculture · AustinConvertible Note
Greencovery
September 2026

Greencovery helps food companies unlock more value from their side-streams by transforming them into high-value, upcycled ingredients.

Food Processing · Wageningen$1.2M Seed
Pointz
September 2022

Pointz is a mobile mapping app that helps navigate bike and scooter riders through safe routes in cities.

Logistics · Providence$500K Pre-Seed

Where MassChallenge invests

Health Care9
Information Technology5
Medical Device5
Medical4
Artificial Intelligence (AI)4
Biotechnology3

About MassChallenge's portfolio

How many companies has MassChallenge invested in?▸

MassChallenge has invested in 1,232 companies tracked in our database. The portfolio spans multiple industries and funding stages, from seed-stage startups to late-stage companies.

What industries does MassChallenge invest in?▸

MassChallenge's top investment sectors include Health Care, Information Technology, Medical Device, Medical, Artificial Intelligence (AI). The firm invests across 62 different industry categories.

What is MassChallenge's largest investment?▸

Among tracked funding rounds, NovaSignal received $37.0M in a Series C round. MassChallenge's total known invested capital is $5.9B.

What is the average investment size for MassChallenge?▸

MassChallenge's average investment size is $7.0M across its portfolio of 1,232 companies.

What are MassChallenge's most recent investments?▸

Recent MassChallenge portfolio additions include DynamiCare Health, Avitus Orthopaedics, INIA Biosciences, Boundless Robotics, TechnoCarbon. These companies were founded in 2020 or later.

Reach the founders behind these 1,232 companies
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