RA Capital Management's Biotechnology Portfolio

IO Biotech is a clinical-stage biotech company developing disruptive immune therapies for the treatment of cancer.

Aktis Oncology is a biotechnology company that designs and develops novel class radiopharmaceuticals.

PepGen is empowering nucleic acid therapeutics to go the distance.

KalVista Pharmaceuticals focuses on developing oral medicines, particularly for managing hereditary angioedema.

Monopar Therapeutics is an emerging biopharmaceutical company focused on developing orphan oncology compounds.

Ceribell focuses on making electroencephalography accessible, efficient, and cost-effective.

Dignify Therapeutics is a drug development company focused on delivering novel drug therapies for bladder and bowel disorders in spinal.

Hyku is a biotech company that develops precise covalent targeting of disease-causing proteins.

HilleVax is a biopharmaceutical company that focuses on the development and commercialization of novel vaccines.

Point Biopharma focused on the development and commercialization of radioligand therapies for the treatment of cancer.

Forge Biologics is a gene therapy development engine, enabling access to life changing gene therapy programs.

Synapse Energy Economics is a consulting firm providing economic and policy analysis for the electric power sector.

Navigator Medicines operate as a biotech company.

Plexium develops a targeted protein degradation platform to find new therapies for cancer and other diseases.

T-knife is a developer of T cell receptors intended for T cell therapy of cancer.

Arvinas advances therapies degrading disease-causing proteins for life-threatening diseases, from discovery to commercialization.

GentiBio is a biotherapeutics company developing engineered regulatory T cells programmed to treat autoimmune allergic diseases.

Alchemab Therapeutics is developing protective antibodies designed to keep people free of hard-to-treat diseases.

Day One Biopharmaceuticals develops targeted therapies to treat people with life-threatening diseases.

Claris Biotherapeutics develops biologic therapies for corneal diseases and other disorders affecting the ocular surface.

Inozyme is a biopharmaceutical company developing therapeutics for rare diseases, with a focus on bone health.

Scribe Therapeutics is a biotech company that develops and engineers new therapeutics based on CRISPR molecules.

Dyne Therapeutics is a developer of targeted therapies intended for serious muscle diseases.

Achilles Therapeutics is a developer of immunotherapies intended to offer next-generation, patient-specific therapies to treat cancer.

Freenome is a biotechnology company developing blood tests for early cancer detection to improve access to routine screening.

Spero Therapeutics develops therapeutics for treatment of gram-negative infections.

Q32 Bio is a biotechnology company that develops treatments for patients with severe autoimmune and inflammatory diseases.

Imara is provider of novel therapeutics for the people living with sickle cell disease and hemoglobinopathies.

Ocelot Bio brings new treatment options to patients with severe liver disease.

Septerna is a biotech firm unlocking diverse drug discovery potential in G protein-coupled receptors across various diseases.

Element Biosciences develops genomic sequencing and multiomics technologies used in drug discovery, and diagnostic applications.

Tango Therapeutics is a biotechnology company that is developing next generation cancer therapies.

Celcuity is a biotechnology company translating discoveries of new cancer sub-types into expanded therapeutic options for cancer patients.

Mineralys Therapeutics is a clinical-stage biopharmaceutical company committed to developing therapy for the treatment of hypertension.

Pyxis Oncology is a biotechnology firm that develops antibody therapeutics intended to promote the body's immune response to cancer.

Blueprint Medicines develops precision therapies for genomically defined cancers and rare diseases.

Black Diamond Therapeutics is a medical company focused on analyzing genetically defined cancers.

Cerebral Therapeutics is a clinical-stage pharmaceutical company.

Medicenna is a clinical stage, privately held, immuno-oncology company.

ALX Oncology is a preclinical stage biotechnology company developing innovative immuno-oncology therapies for cancer.

Frontier Medicines is a biopharmaceutical company that develops a chemoproteomics platform to accelerate the development of medicines.

Helus Pharma is a biopharmaceutical company that develops psychedelic therapeutics for mental health conditions.

Taysha Gene Therapies develops treatments to eradicate severe and life-threatening monogenic diseases of the central nervous system.

NorthLinks Bio is a clinical-stage biopharmaceutical company developing HEX17.

Contraline is a clinical-stage biotechnology company that develops male contraceptive solutions.

Aurinia develops and commercializes therapies to treat targeted patient populations suffering from serious auto-immune diseases.

Aeglea BioTherapeutics is a clinical-stage biotechnology company that develops enzyme therapies for rare metabolic diseases.

Memento Medicines is a biotech developing bispecific antibody therapies for eye diseases.

Legend Biotech is a biopharmaceutical company that develops and commercializes novel cell therapies for oncology.

Moderna Therapeutics is a biotechnology company that develops medicines and vaccines based on messenger RNA (mRNA) technology.

Parabilis Medicines is a Grupo Bugio is a biopharmaceutical firm that specializes in creating medicines.

SonoThera develops ultrasound-based technologies for delivering genetic therapies to targeted tissues.

Artiva Biotherapeutics is a biotech company focused on developing and commercializing allogeneic natural killer (NK) cell therapies.

Avalo Therapeutics is a clinical-stage biopharmaceutical company.

Windward Bio develops monoclonal antibodies for advanced immunological diseases.

Apogee Therapeutics is a biotechnology company that offers therapies for immunological and inflammatory disorders.

Secretome Therapeutics is a clinical-stage cell therapy company that develops therapies for rare cardiac diseases.

Pluton Biosciences tests and discovers microbes for the production of a variety of products, primarily pesticides, and pharmaceuticals.

Icosavax is focused on developing safe and effective vaccines against infectious diseases that address important unmet medical needs.

cAMPfield Therapeutics is a biotechnology company that specializes on exploration and development activities of therapeutic solutions.

Boundless Bio is a precision oncology company that develops therapeutics directed against extrachromosomal DNA in aggressive cancers.

Sana Biotechnology is a developer of engineered cells intended to be used as medicine for patients.

Everest Medicines is dedicated to its mission of developing and commercializing novel transformative pharmaceutical therapies for patients.

Stylus Medicine is on a quest to create disease-treating agents for the next generation based on the groundbreaking work of its founders.

ITeos Therapeutics is a biotechnology company that specializes in tumor immunology, cancer immunotherapy, and drug discovery.

Werewolf Therapeutics operates as an oncology biotherapeutics company.

Acrivon Therapeutics is a precision oncology therapeutics company specializing in drug development through early clinical treatment success.

Incyclix Bio develops small molecule inhibitors of CDKs for the treatment of advanced and resistant cancers.

Stipple Bio is a biotechnology company that offers cellular profiling and target discovery with epitope resolution.

Obsidian Therapeutics is a developer of a next-generation cell and gene therapies created to extend adoptive immunotherapy.

GH Research is a biopharmaceutical company developing novel therapies for the management of mental illness.

Climb Bio occurs when the immune system mistakenly attacks the body's tissues and can result in permanent organ damage or even death.

Adela creates develops technologies centered around detecting high-risk conditions like cancer through routine blood tests.

Edgewise Therapeutics is a clinical-stage biopharmaceutical company focused on the discovery, development and commercialization.

Prelude Therapeutics designs and develops small molecule therapies targeting key drivers of cancer cell growth and resistance.

Ventus Therapeutics develops small molecule drugs that target autoimmune diseases, inflammatory diseases, and cancer.

Terremoto Biosciences is a biotechnology company leveraging the power of lysine-based covalency to develop optimized medicines.

Adcendo is a biotech company that develops antibody-drug conjugates (ADCs) to target cancers with high unmet medical needs.

CDR-Life AG is a biotech company that develops innovative therapeutic antibody fragments with a focus on immuno-oncology.

AN2 Therapeutics focuses on modern biomedical and drug development expertise to provide transformational medicines.

Solid Biosciences is a life science company that conducts research for the treatment of Duchenne muscular dystrophy.

Sionna Therapeutics is developing novel small molecule therapies to treat cystic fibrosis (CF).

Orchard Therapeutics is a biotechnology company dedicated to assisting patients through innovative gene therapies.

Atavistik Bio is a biotechnology company that develops precision allosteric small molecules aimed at treating metabolic diseases and cancer.

Palisade Bio is a clinical-stage biopharmaceutical company that develops therapies for acute and chronic gastrointestinal complications.

Vor Biopharma is an immuno-oncology company that develops therapies for treating cancer.

OnKure is a clinical-stage biopharma company developing precision medicines targeting validated cancer drivers.

Stoke is developing antisense oligonucleotide medicines that target RNA splicing to increase gene expression for treatment.

Pinnacle Medicines is a peptide drug discovery company that provides peptide modality for medical needs.

Terrestrial Bio engages in developing biomedical innovations with a focus on improving access to vaccines.

Nkarta Therapeutics is a developer of cell engineering platform created to build the next generation of cell therapies.

Surrozen is a biopharmaceutical that focuses on unlocking the body’s regenerative power to treat injury and disease.

Candid Therapeutics develops therapies for autoimmune diseases using antibody-based technologies that modulate immune system activity.

Capstan Therapeutics develops in vivo mRNA and gene-editing medicines for a broad range of diseases.

Inhibrx is a clinical-stage biotechnology company that focuses on developing a broad pipeline of biologic therapeutic candidates.

SAB Biotherapeutics is a clinical-stage biopharmaceutical development company.

Ovid Therapeutic's purpose is to solve intractable medical problems.

Curevo is a clinical-stage biotechnology company developing next-generation, non-mRNA vaccines for infectious diseases.

Unicycive Therapeutics provides development programs that focus on treating kidney diseases with unmet medical needs.

Equillium is a biotechnology company that develops products for autoimmune and inflammatory disorders with an unmet medical need.

NAPIGEN is a biotechnology company that addresses novel genome engineering of various organisms such as plants, microbes, and animals.

Dianthus Therapeutics is a biotech company developing new treatments for serious autoimmune diseases using a more targeted approach.

Angitia Biopharmaceuticals develops biologic therapies for musculoskeletal diseases.

Arcutis Biotherapeutics is a clinical-stage biopharmaceutical company focused on developing medical dermatology for unmet needs.

Compass Pathways is a mental health care company that focuses on developing therapies for treatment-resistant depression.

Zura Bio is a clinical-stage, multi-asset biotechnology company.

Bicara Therapeutics develops dual-action cancer therapies, combining targeted treatments with tumor modulators for enhanced impact.

Tyra Biosciences is a biotechnology company targeting new pathways of acquired resistance in oncology with purpose-built drugs.

Genetix Biotherapeutics develops and delivers approved gene therapies for severe rare genetic diseases like sickle cell.

Synthego is a genome engineering company that enables access to CRISPR to accelerate life science research and development.

Avilar Therapeutics is a biopharmaceutical company focusing on extracellular protein degradation.

Immunic is a biopharmaceutical company that develops a pipeline of selective oral immunology therapies.

Coherus Biosciences develops, manufactures, and commercializes biologic therapeutics for oncology and inflammatory diseases.

Evommune is a biotechnology company that develops therapeutics that halt progressive disease and address their symptoms.

Abcuro develops immunotherapies to treat autoimmunity and cancer.

Xilio Therapeutics is a biotechnology company that develops tumor-activated immuno-oncology therapies.

Galecto is a clinical stage biotechnology company focused on the development of novel treatments for fibrosis and cancer.

ILiAD is a clinical-stage biotechnology company focused on the prevention and treatment of disease caused by Bordetella Pertussis.

Hemab is a clinical-stage biotech company that develops prophylactic biologic therapies for underserved bleeding and thrombotic.

VitriVax is a formulation technology company that engineers solutions to maximize the accessibility and utility of human vaccines.

Adcytherix is a biopharmaceutical firm that specializes in the development of new antibody drug conjugates (ADC).

Indapta Therapeutics is a privately held biotechnology company.

Ansa Biotechnologies develops a novel DNA synthesis technology based on enzymes.

Sparrow Pharmaceuticals is a clinical-stage biopharmaceutical company developing treatments for disorders of corticosteroid excess.

Delix Therapeutics focuses on harnessing the power of psychoplastogens novel neuroplasticity-promoting therapeutic.

Gameto is a biotechnology company developing therapeutics of the female reproductive system using cell engineering.

Imbria Pharmaceuticals is a clinical stage biotechnology company developing novel therapies for cardiometabolic diseases.

Vaxess Technologies engages in developing biomedical innovations with a focus on improving access to vaccines.

Vivace Therapeutics is a venture-backed start-up dedicated to discovering and developing cancer therapeutics by targeting a novel pathway.

Bambusa Therapeutics operates as biotechnology company.

AmbAgon Therapeutics is a developer of cancer molecule therapeutics.

Trace Neuroscience is a biopharmaceutical company that aims to extend the promise of genetic medicine to patients.

Superluminal Medicines is a generative biological and chemical company that innovates drug discovery and development processes.

Elektrofi is a preclinical-stage company dedicated to redefining the standard of drug delivery by transforming the patient experience.

Halda Therapeutics is a research-stage drug discovery company.

Idrx is a clinical-stage biopharmaceutical that develops oncology-based precision therapies to treat cancer.

MBX Biosciences is a preclinical-stage biotech company that creates therapies to treat rare endocrine diseases.

Outpace Bio develops innovative cell therapies to enhance cancer treatment efficacy.

Bright Peak is a biotech company that develops a portfolio of immunotherapies for the treatment of cancer and autoimmune diseases.

Interius BioTherapeutics is a biopharmaceutical company that develops in vivo cell-specific gene medicines to treat B cell lymphomas.

Ajax Therapeutics is a biotechnology company developing therapies to target cytokine signaling pathways that drive hematologic malignancies.

Bluejay Therapeutics is a private biopharmaceutical company focused on the development of cures for infectious diseases.

Asher Bio is a biotechnology company that specializes in the fields of therapeutics builds better immunotherapy for cancer.

SeLux Diagnostics is a developer of a next-generation phenotyping platform that provides personalized antimicrobial therapies to patients.

ProfoundBio is a developer of targeted therapeutics intended for patients with cancer.

Rampart Bioscience develops gene medicines to provide long-lasting treatments for a wide range of diseases.

Mariana Oncology is a biotechnology research industry.

ExcepGen is solving fundamental underlying problems in drug discovery to create a new generation of therapeutics.