RA Capital Management's Therapeutics Portfolio

IO Biotech is a clinical-stage biotech company developing disruptive immune therapies for the treatment of cancer.

Monopar Therapeutics is an emerging biopharmaceutical company focused on developing orphan oncology compounds.

Spero Therapeutics develops therapeutics for treatment of gram-negative infections.

Dignify Therapeutics is a drug development company focused on delivering novel drug therapies for bladder and bowel disorders in spinal.

Point Biopharma focused on the development and commercialization of radioligand therapies for the treatment of cancer.

Forge Biologics is a gene therapy development engine, enabling access to life changing gene therapy programs.

Synapse Energy Economics is a consulting firm providing economic and policy analysis for the electric power sector.

Plexium develops a targeted protein degradation platform to find new therapies for cancer and other diseases.

Arvinas advances therapies degrading disease-causing proteins for life-threatening diseases, from discovery to commercialization.

Iterum Therapeutics is a clinical-stage pharmaceutical company that develops significantly differentiated anti-infectives.

Achilles Therapeutics is a developer of immunotherapies intended to offer next-generation, patient-specific therapies to treat cancer.

LENZ Therapeutics operates as an organization engaged in the late-stage clinical development of pharmaceuticals for the eyes.

Imara is provider of novel therapeutics for the people living with sickle cell disease and hemoglobinopathies.

Tango Therapeutics is a biotechnology company that is developing next generation cancer therapies.

Jade Biosciences is developing transformative therapies to redefine the standard of care for inflammation and immunology indications.

Celcuity is a biotechnology company translating discoveries of new cancer sub-types into expanded therapeutic options for cancer patients.

Cerebral Therapeutics is a clinical-stage pharmaceutical company.

Medicenna is a clinical stage, privately held, immuno-oncology company.

ALX Oncology is a preclinical stage biotechnology company developing innovative immuno-oncology therapies for cancer.

Frontier Medicines is a biopharmaceutical company that develops a chemoproteomics platform to accelerate the development of medicines.

Ollin Biosciences develops ophthalmic therapies focused on treating serious vision-threatening diseases.

Aurinia develops and commercializes therapies to treat targeted patient populations suffering from serious auto-immune diseases.

Aeglea BioTherapeutics is a clinical-stage biotechnology company that develops enzyme therapies for rare metabolic diseases.

Scribe Therapeutics is a biotech company that develops and engineers new therapeutics based on CRISPR molecules.

Legend Biotech is a biopharmaceutical company that develops and commercializes novel cell therapies for oncology.

Moderna Therapeutics is a biotechnology company that develops medicines and vaccines based on messenger RNA (mRNA) technology.

Artiva Biotherapeutics is a biotech company focused on developing and commercializing allogeneic natural killer (NK) cell therapies.

Avalo Therapeutics is a clinical-stage biopharmaceutical company.

Secretome Therapeutics is a clinical-stage cell therapy company that develops therapies for rare cardiac diseases.

Q32 Bio is a biotechnology company that develops treatments for patients with severe autoimmune and inflammatory diseases.

Apogee Therapeutics is a biotechnology company that offers therapies for immunological and inflammatory disorders.

Boundless Bio is a precision oncology company that develops therapeutics directed against extrachromosomal DNA in aggressive cancers.

Werewolf Therapeutics operates as an oncology biotherapeutics company.

Acrivon Therapeutics is a precision oncology therapeutics company specializing in drug development through early clinical treatment success.

Incyclix Bio develops small molecule inhibitors of CDKs for the treatment of advanced and resistant cancers.

Prelude Therapeutics designs and develops small molecule therapies targeting key drivers of cancer cell growth and resistance.

Ventus Therapeutics develops small molecule drugs that target autoimmune diseases, inflammatory diseases, and cancer.

Adcendo is a biotech company that develops antibody-drug conjugates (ADCs) to target cancers with high unmet medical needs.

Claris Biotherapeutics develops a topical formulation intended to cure corneal wounds, ulcers, and scars.

Sionna Therapeutics is developing novel small molecule therapies to treat cystic fibrosis (CF).

NexCure offers clinically intense therapies in outpatient, community settings, and other cutting-edge treatments.

Atavistik Bio is a biotechnology company that develops precision allosteric small molecules aimed at treating metabolic diseases and cancer.

OnKure is a clinical-stage biopharma company developing precision medicines targeting validated cancer drivers.

Palisade Bio is a clinical-stage biopharmaceutical company that develops therapies for acute and chronic gastrointestinal complications.

Stoke is developing antisense oligonucleotide medicines that target RNA splicing to increase gene expression for treatment.

Pinnacle Medicines is a peptide drug discovery company that provides peptide modality for medical needs.

Candid Therapeutics develops therapies for autoimmune diseases using antibody-based technologies that modulate immune system activity.

Capstan Therapeutics develops in vivo mRNA and gene-editing medicines for a broad range of diseases.

Inhibrx is a clinical-stage biotechnology company that focuses on developing a broad pipeline of biologic therapeutic candidates.

SAB Biotherapeutics is a clinical-stage biopharmaceutical development company.

Arcutis Biotherapeutics is a clinical-stage biopharmaceutical company focused on developing medical dermatology for unmet needs.

Bicara Therapeutics develops dual-action cancer therapies, combining targeted treatments with tumor modulators for enhanced impact.

Tyra Biosciences is a biotechnology company targeting new pathways of acquired resistance in oncology with purpose-built drugs.

Immunic is a biopharmaceutical company that develops a pipeline of selective oral immunology therapies.

Coherus Biosciences develops, manufactures, and commercializes biologic therapeutics for oncology and inflammatory diseases.

Abcuro develops immunotherapies to treat autoimmunity and cancer.

Xilio Therapeutics is a biotechnology company that develops tumor-activated immuno-oncology therapies.

VitriVax is a formulation technology company that engineers solutions to maximize the accessibility and utility of human vaccines.

Ansa Biotechnologies develops a novel DNA synthesis technology based on enzymes.

Star Therapeutics mission is to develop therapies for as many diseases as possible for millions of patients.

Sparrow Pharmaceuticals is a clinical-stage biopharmaceutical company developing treatments for disorders of corticosteroid excess.

Vivace Therapeutics is a venture-backed start-up dedicated to discovering and developing cancer therapeutics by targeting a novel pathway.

Elektrofi is a preclinical-stage company dedicated to redefining the standard of drug delivery by transforming the patient experience.

Halda Therapeutics is a research-stage drug discovery company.

MBX Biosciences is a preclinical-stage biotech company that creates therapies to treat rare endocrine diseases.

Bright Peak is a biotech company that develops a portfolio of immunotherapies for the treatment of cancer and autoimmune diseases.

Interius BioTherapeutics is a biopharmaceutical company that develops in vivo cell-specific gene medicines to treat B cell lymphomas.

Asher Bio is a biotechnology company that specializes in the fields of therapeutics builds better immunotherapy for cancer.

SeLux Diagnostics is a developer of a next-generation phenotyping platform that provides personalized antimicrobial therapies to patients.

ProfoundBio is a developer of targeted therapeutics intended for patients with cancer.

Rampart Bioscience develops gene medicines to provide long-lasting treatments for a wide range of diseases.

Expansion Therapeutics is a biotechnology company focusing on developing transformative oral medicines for severe RNA-mediated diseases.

Diagonal Therapeutics is a biotechnology startup that develops targeted therapies for cancer and genetic diseases.

Synthekine is a development stage biotherapeutics company focused on the engineering of novel specific and potent cytokine therapies.

Metagenomi uses metagenomics and machine learning to discover novel genome editing systems for therapeutics development.

Wave Life Sciences is a clinical-stage RNA medicines company committed to delivering life-changing treatments for people battling diseases

Tourmaline Bio is a biotechnology company that develops medicines to treat inflammatory and immune diseases in patients.

Protara Therapeutics develops transformative therapies for people with cancer and rare diseases with limited treatment options.

Triana Biomedicines is a developer of a molecular glue discovery platform to regulate disease.

Janux Therapeutics develops immunotherapies that generates immune responses to prevent tumors and not affecting a patient’s healthy tissue.

TScan Therapeutics is a biopharmaceutical company focused on the development of immunotherapy treatments for cancer.

Ambros Therapeutics is a clinical-stage biotechnology company.

GBT is a clinical-stage biopharmaceutical company developing a therapy for sickle cell disease.

BioAge Labs is a clinical-stage biotechnology company that develops therapeutics to treat obesity and metabolic diseases.

Tenaya Therapeutics a clinical-stage biotechnology company that develops novel therapies to treat heart diseases.

Antios Therapeutics is a biopharmaceutical company developing innovative therapies for viral diseases.

NanoMosaic provides solutions for early illness detection, prognostic monitoring, and biomarker identification.

Lusaris Therapeutics develops small-molecule neuroplastogen therapeutics for neuropsychiatric and neurological disorders.

Cortica provides neurological therapies for children with autism and other developmental differences.

Invivyd develops antibodies to transcend the limitations of the human immune system and fight against viral infections.

Jnana Therapeutics develops innovative therapies using a chemoproteomics drug discovery platform.

ALENTIS Therapeutics is a Swiss-French biotech company developing novel therapeutics in advanced liver disease and cancer.

Kinaset Therapeutics is a biopharma company that focuses on advancement of novel drugs in areas of unmet medical needs.

Affinia Therapeutics is a biotechnology company developing transformative AAV gene therapies for people with rare and prevalent diseases.

Cidara Therapeutics develops targeted immunotherapies aimed at improving treatment outcomes for patients with serious diseases.

Ervaxx is illuminating the immune interface to develop new cancer therapies.

Seres Therapeutics is a microbiome therapeutics company that develops treatments for serious diseases.

Cedilla Therapeutics is a biotechnology company that develops targeted small molecules for the treatment of cancer and other diseases.

Harpoon Therapeutics is a clinical-stage immunotherapy company focused on the development of novel T-cell recruiting biologic therapies.

Rani is a clinical-stage biotherapeutics company that enables the development of orally administered biologics to improve patient outcomes.

C4 Therapeutics develops novel early stage therapies that eliminate disease-causing proteins.

LEXEO Therapeutics utilizes gene therapy to treat genetically defined cardiovascular and central nervous system diseases.

Cerevel Therapeutics is a biopharmaceutical company that develops drugs to treat neurological and neuropsychiatric disorders.

Slate Medicines develops therapeutics that target Pituitary Adenylate Cyclase-Activating Polypeptide for migraine treatment and prevention.

Satsuma Pharmaceuticals is a clinical-stage biopharmaceutical company engaged in developing a novel therapeutic product.

DTx Pharma is a biotechnology company creating novel RNA-based therapeutics to treat the genetic drivers of disease.

Vividion is a developer of a novel drug discovery platform designed to offer transformative treatments to patients with serious illnesses.

Locana develops RNA-targeting gene therapies for patients with severe neurodegenerative, neuromuscular, and retinal diseases.

Aimmune Therapeutics is a clinical-stage biopharmaceutical company that improves the lives of people with food allergies.

Prevail Therapeutics is a biotechnology company focused on developing novel gene therapies for patients with Parkinson’s disease.

Peloton Therapeutics, a biotech company based in Dallas, is involved in discovering and developing novel drugs for cancer treatments.

Medeor Therapeutics is a biotechnology company that dedicates to dedicates to the development of personalized cellular immunotherapies.

Lumena Pharmaceuticals develops oral therapeutics for rare liver diseases to improve liver function and relieve disease symptoms.